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Non-viscous medical use liquid embolic agent

A liquid embolizing agent, non-adhesive technology, applied in medical science, surgery, etc., can solve the problems of inconvenient surgical operation and adhesion of microcatheter to the blood vessel wall, and achieve the purpose of reducing usage, reducing vascular toxicity, and being easy to operate. Effect

Active Publication Date: 2007-04-18
SAIKE SAISI BIOTECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the existing NBCA embolic material still has the disadvantage of "sticky tube", that is, due to its adhesiveness, it is very easy to adhere the microcatheter to the blood vessel wall after injection, which brings inconvenience to the operation. In addition, the monomer Heat is released during polymerization, which is also a shortcoming of this plug material

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] Ethylene-vinyl alcohol copolymer was baked at 100°C for 5 hours before use, then 2.0g ethylene-vinyl alcohol copolymer (vinyl content was 10%) was dissolved in a mixed solvent of 100ml dimethyl sulfoxide and ethanol (the amount of ethanol The amount is 5.0ml), after the polymer is completely dissolved, put it into an ampoule bottle for use.

Embodiment 2

[0030]Ethylene-vinyl alcohol copolymer was baked at 100°C for 5 hours before use, then 3.0g ethylene-vinyl alcohol copolymer (vinyl content was 35%) was dissolved in a mixed solvent of 100ml dimethyl sulfoxide and ethanol (the amount of ethanol Amount is 35ml), after the polymer dissolves completely, put into the ampoule bottle, stand-by.

Embodiment 3

[0032] Ethylene-vinyl alcohol copolymer was baked at 100°C for 5 hours before use, then 5.0g ethylene-vinyl alcohol copolymer (vinyl content was 35%) was dissolved in a mixed solvent of 100ml dimethyl sulfoxide and ethanol (the amount of ethanol Amount is 13ml), after the polymer dissolves completely, put into the ampoule bottle, stand-by.

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Abstract

A non-adhesive liquid-state embolizing agent for treating cerebral arteriovenous malformation (AVM) and aneurysm is composed of the water-insoluble organic polymer soluble to organic solvent containing alcohol and the medical developer.

Description

technical field [0001] The invention relates to a medical liquid composition, in particular to a liquid embolic agent which can be used as an embolic material in medical treatment. Background technique [0002] In medical treatment, transcatheter embolization is an important technique in interventional therapy and one of the three major techniques of interventional radiology. It is to controlly inject some artificial embolic materials into the supply vessels of lesions or organs or into the diseased blood vessels to make them occluded and interrupt the blood supply, so as to control bleeding, treat vascular lesions, tumors, and eliminate the function of diseased organs. Purpose. [0003] Cerebral arteriovenous malformation (brain AVM) and aneurysm are the most common hemorrhagic cerebrovascular diseases in clinical practice. They are prone to epileptic convulsions, neurological dysfunction and rupture and bleeding. Difficulties in neurosurgery. With the continuous develop...

Claims

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Application Information

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IPC IPC(8): A61L31/18A61L31/04
Inventor 夏毅然贺红卫张静波罗西友姜除寒
Owner SAIKE SAISI BIOTECH CO LTD
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