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Chinese medicinal composition for treating traumatic diseases, its preparation method and quality control method

A quality control method and composition technology, which can be used in drug combinations, pharmaceutical formulas, bone diseases, etc., and can solve problems such as toxic reactions, long medication cycles, and mercury accumulation poisoning

Inactive Publication Date: 2007-04-25
黄华
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] In the Chinese patent application document whose publication number is CN1709463A, a kind of medicine for traumatic diseases is disclosed. ), chicken bone (burning), natural copper (calcining), frankincense (burning), cinnabar, melon seeds, borneol and other twelve herbs. According to the applicant's common sense and experience analysis, the drug has a relatively large presence in practical application. As stated in the application, the cinnabar in the raw material medicine is a mineral drug, mainly containing mercury sulfide (HgS). The current version of the "Chinese Pharmacopoeia" stipulates that it should not be added to the decoction, in case the temperature exceeds 40 °C, lead to increased toxicity; in fact, the applicant should also note that if the drug is made into tablets, it must go through the process of tablet compression. Mercury toxicity appears; if it is made into capsules and pills, the high temperature phenomenon in the process of drying, packaging, storage and transportation cannot be avoided, which may cause toxic reactions; Long, if this kind of medicine is used improperly, it is also prone to cumulative poisoning of mercury

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0077] Prescription: safflower 50g, wood beetle 300g, nuxonum powder 150g

[0078] Myrrh 30g Notoginseng 600g Starfish 150g

[0079] Chicken bone 300g ice flakes 10g natural copper 150g

[0080] Frankincense 10g Melon Seeds 10g

[0081] Preparation method: the above medicinal flavors are made into fine powder together with ground beetle, natural copper, frankincense, and myrrh, passed through a 100-mesh sieve, and set aside. Grind safflower, panax notoginseng, starfish, chicken bones, and melon seeds into coarse particles, add water to decoct twice for 2 hours each time, filter, combine the filtrates, concentrate under reduced pressure to a thick paste with a relative density of 1.30°C, and dry under reduced pressure , the resulting dry paste is crushed into fine powder and passed through a 100-mesh sieve. Mix the two parts of fine powder evenly, add borneol, 100g of starch and 1g of hypromellose, make pills with water, and coat to obtain.

Embodiment 2

[0083] Prescription: 150g of safflower, 500g of ground beetle, 300g of nutmeg powder

[0084] Myrrh 60g Notoginseng 1000g Starfish 300g

[0085]Chicken bone 600g ice flakes 30g natural copper 300g

[0086] Frankincense 50g Melon Seeds 50g

[0087] Preparation method: For the above medicinal taste, add 40g of safflower and starch, add water to make a paste, mix well, and after drying, make a fine powder with Panax notoginseng, starfish, ground beetle, chicken bone, natural copper, frankincense, myrrh, and melon seeds , passed through a 100-mesh sieve, and set aside. Blend the Nuxychnium seed powder into the spare fine powder of various medicines according to the prescription ratio, mix well, and granulate the uniformly mixed medicine powder with 1% hydroxypropylmethylcellulose in 50% ethanol solution, and dry (60°C) , granulate, add borneol, 1g of magnesium stearate and appropriate amount of starch, until the total amount is 3500g, mix well, and press into tablet...

Embodiment 4

[0089] Prescription: 120g of safflower, 400g of ground beetle, 200g of nutmeg powder

[0090] Myrrh (broiled) 40g Notoginseng 800g Starfish (broiled) 200g

[0091] Chicken bone (burnt) 400g borneol 20g natural copper 200g

[0092] Roasted frankincense 40g Melon seeds 40g

[0093] The preparation method is the same as in Example 1.

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Abstract

The invention provides a Chinese medicinal composition for traumatological diseases, which is prepared from raw material herbs including safflower, wood louse, seed of nuxvomica powder, myrrh, notoginseng, starfish, Canton love-pea vine, boneol, native copper, frankincense, sweet melon seeds. The invention also discloses the method for preparing the Chinese medicinal composition and its quality control method.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition and a preparation method thereof, in particular to a traditional Chinese medicine composition for treating bruises and a preparation method thereof, belonging to the field of traditional Chinese medicines. Background technique [0002] As we all know, the etiology of orthopedic diseases is mostly related to trauma, and the pathogenesis is mostly blood stasis and blood deficiency. Symptoms such as anorexia, abdominal distension, and slightly hard stools are caused by damage to muscles and bones, stagnation of Qi and blood stasis. In recent years, clinical and experimental studies have also shown that symptoms such as pain and fever in the early stage of fracture are mainly caused by increased local vascular permeability and inflammatory tissue exudation after trauma. Drugs for the above symptoms should have the ability to promote gastrointestinal motility, Reduce vascular permeability,...

Claims

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Application Information

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IPC IPC(8): A61K36/56A61P19/08A61K35/64A61K35/56A61K35/32A61K33/34A61K31/045A61K35/57A61K35/616
Inventor 高淑英
Owner 黄华
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