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Effervescence tablet for treating colpitis, preparation method and use thereof

An effervescent tablet and vaginitis technology, applied in the field of external effervescent tablets, can solve the problems of affecting the curative effect, bacteria easily forming drug resistance, toxic and side effects, etc., and achieve the effects of improving the therapeutic effect, protecting the self-cleaning ability of the genitals, and facilitating medication

Inactive Publication Date: 2007-05-30
阿不力克木·买买提明
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the products that suppress vaginal inflammation in women are mainly chemical drugs. Although they have good curative effect, they also have certain toxic and side effects, and bacteria are prone to develop drug resistance.
Although the commercially available external preparations of traditional Chinese medicine can relieve symptoms to varying degrees, their inhibitory effect on pathogens is not ideal.

Method used

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  • Effervescence tablet for treating colpitis, preparation method and use thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0155] Coptidis 50g Nuxseed 20g Smilax 200g

[0156] Curcuma 140g Gallat 170g Pomegranate peel 140g

[0157] β-cyclodextrin 40g Sodium bicarbonate 150g Polyethylene glycol 50g

[0158] Citric acid 300g Magnesium stearate 10g Lactose 50g

[0159] Sodium carboxymethyl starch 200g

[0160] a. Crush 140 g of the raw material curcuma zedoary into a coarse powder, add 5 times the amount of water, extract the volatile oil for 0.3 hours, carry out inclusion inclusion of the volatile oil with 5 g of β-cyclodextrin, keep the temperature at 15°C, stir for 0.1 hour, suction filter, and dry for 0.2 hour, Grind finely, pass through a 20-mesh sieve, and set aside;

[0161] b. Crushing 50 g of Coptidis rhizome and 20 g of Nuxychnium chinensis into coarse powder, adding 3 times the amount of 30% ethanol to reflux extraction once for 0.1 hour, combining the filtrates, concentrating under reduced pressure to obtain extract, and set aside;

[0162] c. Combine 200 g of the raw material Smilax ...

Embodiment 2

[0167]a. Crush 250g of the raw material curcuma curcuma into coarse powder, add 8 times the amount of water, extract the volatile oil for 3 hours, carry out inclusion inclusion of the volatile oil with 20g of β-cyclodextrin, keep the temperature at 20°C, stir for 1.0 hour, filter with suction, dry and finely grind , through a 60-mesh sieve, and set aside;

[0168] b. Grinding 200 g of Coptidis Rhizome and 80 g of Nuxychnium Chinensis into coarse powder, adding 8 times the amount of 50% ethanol to reflux extraction twice, each time for 1.5 hours, combining the filtrates, concentrating under reduced pressure to an extract, and set aside;

[0169] c. Combine 350g of the raw material sarsaparilla, 260g of gall, 250g of pomegranate peel and the dregs extracted from steps a and b, add 8 times the amount of water and decoct twice for 1 hour each time, combine the filtrate, concentrate under reduced pressure, and set aside ;

[0170] d, combine step c and step b extract, mix well, sp...

Embodiment 3

[0174] a. Crush 360g of the raw material Curcuma curcuma into coarse powder, add 10 times the amount of water, extract the volatile oil for 10 hours, carry out inclusion inclusion of the volatile oil with 200g of β-cyclodextrin, keep the temperature at 25°C, stir for 2.5 hours, filter with suction, dry, and grind finely , passed through a 100-mesh sieve, and set aside;

[0175] b. Crushing 300 g of Coptidis rhizome and 100 g of Nuxychnium chinensis into coarse powder, adding 10 times the amount of 85% ethanol to reflux extraction for 3 times, each time for 2.5 hours, combining the filtrates, concentrating under reduced pressure to an extract, and set aside;

[0176] c. Combine 450g of raw materials Smilax smilax, 430g of gall, 460g of pomegranate peel with the dregs extracted from steps a and b, add 15 times the amount of water to decoct 3 times, each time for 2.5 hours, combine the filtrate, concentrate under reduced pressure, and set aside ;

[0177] d, combine step c and s...

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Abstract

The invention relates to a effervescent preparation for treating women's vaginitis, which is prepared from raw material herbs of goldthread root, seed of nuxvomica, smilax China root, zedoary, oak-apple, pomegranate bark, beta cyclodextrin, sodium hydrogen carbonate, polyethylene glycol, lactose, citric acid, magnesium stearate and sodium carboxymethylstarch.

Description

technical field [0001] The invention relates to an external effervescent tablet for treating women's vaginitis Background technique [0002] Vaginitis is a very common gynecological disease. Because the vagina is located in a hidden part of the human body and communicates with the outside world, it is very easy to cause external microbial infection. Western medicine divides it into non-specific vaginitis, candida vaginitis, senile vaginitis and so on. Normally, there are some resident flora in the vagina. When the body's resistance is low or the vaginal mucosa is damaged or the pH of the vagina changes, these bacteria can multiply or foreign pathogenic bacteria can invade and cause vaginitis. Staphylococcus, Escherichia coli, Candida albicans, and protozoa are common pathogens that cause vaginal infections. Traditional Chinese medicine believes that the combination of dampness and heat, internal and external dampness stains, or infection with genital worms, the three are ...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61K9/20A61K9/46A61P15/02A61K35/64
Inventor 阿不力克木·买买提明
Owner 阿不力克木·买买提明
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