Preparing method for extracts of red clover

A technology for red clover and extract is applied in the field of preparation of red clover extract, which can solve the problems of large influence of isoflavone refining and low content of active ingredients, etc., and achieve the effect of saving production cost.

Active Publication Date: 2007-06-20
湖南省中药提取工程研究中心有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the inventors found that the content of the active ingredients in the dried red clover in the above state is not high, which has a great influence on the subsequent refining of isoflavones
In addition, the general process has no requirements on the harvesting season of the raw materials, and no one has made relevant research on how to keep the active ingredients in the red clover raw materials to the maximum extent.

Method used

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  • Preparing method for extracts of red clover

Examples

Experimental program
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Effect test

Embodiment 1

[0026] Select the above-ground part of the red clover plant in a fresh state, without verticillium wilt, without decay, and in the flower bud stage, chop it up, and extract it twice with 80% ethanol twice the weight of the fresh medicinal material, for 2 hours each time . The extracts were combined, recovered, concentrated, cooled, and allowed to stand to separate to obtain a precipitate, and the precipitate was dried to obtain a red clover extract with a total isoflavone content of 17%.

Embodiment 2

[0028] Select the above-ground part of the red clover plant in the fresh state, without verticillium wilt, without rot, and in the bud stage, chop it up, and use 90% ethanol twice the weight of the fresh medicinal material to extract twice, each time for 2 hours . Combine the extracts, concentrate, cool, and stand to separate to obtain a precipitate, and dry the precipitate to obtain a red clover extract with a total isoflavone content of 20%.

Embodiment 3

[0030] Select the above-ground part of the red clover plant in the fresh state, without verticillium wilt, without rot, and in the bud stage, chop it up, and extract it twice with 95% ethanol twice the weight of the fresh medicinal material, for 2 hours each time . The extracts were combined, concentrated, cooled, and allowed to stand to separate to obtain a precipitate, and the precipitate was dried to obtain a red clover extract with a total isoflavone content of 22.4%.

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Abstract

An extract of red clover herb rich in isoflavone is prepared from fresh red clover herb through extracting in alcohol, recovering alcohol, concentrating the extracted liquid, laying aside to obtain deposit, and drying.

Description

technical field [0001] The invention relates to a plant extract, in particular to a process for preparing red clover extract by using fresh raw materials. Background technique [0002] Red clover (Trifolium pratense L.) is a perennial herbaceous plant of the genus Trifolium in the family Leguminosae, also known as red clover and red clover. The wild species has been planted in the southern provinces of the Yangtze River Basin in recent years. Red clover is originally an excellent pasture for livestock. Recent research results show that its inflorescences and flowering branches and leaves contain a large amount of isoflavones. The dihydroxyphenolic structure of red clover isoflavones is similar to the structure of estrogen in animals. Therefore, Has estrogen-like effects. Isoflavones act as estrogen agonists when the level of endogenous estrogen in the body is low; while when the level of estrogen in the body is high, it occupies the estrogen receptor and acts as an anti-es...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/48A61P15/12A61P19/10A61P35/00A61K135/00A61K133/00A61K127/00
Inventor 曾建国缪建荣罗琪罗练辉
Owner 湖南省中药提取工程研究中心有限公司
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