Infusion treatment agents, catheters, filter devices, and occlusion devices, and use thereof

Abstract

Embodiments include an infusion-occlusion system having a delivery catheter, a guide catheter adapted to receive the delivery catheter, and a guidewire with an occlusion device adapted to be received within the guide catheter. The guide catheter of the catheter kit may be provided with an occlusion device at the distal end of the guide catheter. The delivery catheter may have an accessory lumen, coaxial and/or co-linear lumen, a supporting mandrel, and/or an occlusion device at its distal end. Moreover, according to embodiments, occlusion devices may be a single material or a composite balloon having an inner liner and an outer layer of different materials, a high compliance low pressure balloon, and/or a filter device that restricts particles from passing through but does not restrict fluid, such as blood. An inflation device with a large volume and low volume syringe can be used to inflate the balloon.

Description

FIELD Cardiovascular catheters and occlusion devices. BACKGROUND It is increasingly important that a physician or surgeon delivering substances, such as a treatment agent or drug, is able to efficiently and accurately locate the desired target tissue for effective delivery of the substance. This is particularly true when the concentration of the substance required at the target site cannot be safely or effectively achieved by introduction of the substance to a location remote from the target site. Moreover, the physician may only want to treat the diseased portion of an organ or tissue and avoid treating the healthy portions. Such localized treatment is desired not only for substance delivery but is necessary for other treatments, such as myocardial revascularization. Myocardial revascularization is a procedure in which “holes” are formed in ischemic ventricular tissue to increase blood flow to the treated area. It is thought that the tissue damage (e.g., holes) encourages growth...

AI Technical Summary

Benefits of technology

In one embodiment, there is disclosed an infusion-occlusion system for infusing a treatment agent to a region of interest of an artery or vein (including a blood vessel of the human heart) that includes a delivery catheter, a guide catheter adapted to receive the delivery catheter, a pressure increasing device adapted to be connected to the delivery catheter, a pressure-sensing device adapted to be connected to the delivery catheter, an i

Problems solved by technology

This is particularly true when the concentration of the substance required at the target site cannot be safely or effectively achieved by introduction of the substance to

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