Solid surface for biomolecule delivery and high-throughput assay

a biomolecule and solid surface technology, applied in the field of solid surface for biomolecule delivery and highthroughput assay, can solve the problems of limiting the application of viral vectors in vitro, affecting the safety of viral vectors, and complicated and expensive process for viral vector preparation
US20070020761A1Inactive Publication Date: 2007-01-25YU LEI +3
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Patent Information

Authority / Receiving Office
US · United States
Current Assignee / Owner
YU LEI
Publication Date
2007-01-25
Estimated Expiration
Not applicable · inactive patent

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Abstract

The present invention is related to a method for introducing biomolecules, such as nucleic acids, into cells by culturing cells on a solid surface which is coated with a transfection reagents and biomolecules.
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Description

RELATED APPLICATIONS

[0001] This application is a divisional of U.S. application Ser. No. 10 / 341,059 filed Jan. 13, 2003 which is incorporated herein by reference.FIELD OF THE INVENTION

[0002] The present invention is related to a method for introducing biomolecules, such as nucleic acids, into cells by culturing cells on a solid surface which is coated with a transfection reagents and biomolecules for routine transfection assays and high-throughput transfection assays. The present invention is also related to method of use and method of making the transfectable surface for such assays. BACKGROUND OF THE INVENTION

[0003] Gene transfection methods can be used to introduce nucleic acids into cells and are useful in studying gene regulation and function. High throughput assays that can be used to screen large sets of DNAs to identify those encoding products with properties of interest are particularly useful. Gene transfection is the delivery and introduction of biologically functional...

Claims

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