Method for measurably improving oral health
a technology for improving oral health and measuring the effect of oral health, which is applied in the field of measuring oral health, can solve the problems of serious health problems, poor oral health affects millions of people every year, and inability to use, so as to improve oral health, improve oral health, and improve oral health. , the effect of improving the indices of oral health
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[0069] The following non-limiting examples illustrate measurable improvements in various indices using the method in accordance with various embodiments of the invention. These example are merely illustrative, and it is not intended that the invention be limited to the examples. Compositions for use in accordance with the present invention may include the ingredients listed below as well as additional and / or alternative inert materials, preservatives, and other constituents typically found in compositions for promoting oral health. In the case where exemplary inert materials and / or preservatives are listed, these ingredients are merely exemplary, and it is understood that other similar ingredients may be substituted for the materials listed in the examples below.
example 1
Reduction in V-MI
[0070] A pale light pink viscous gel, having a viscosity of about 40,000 cp, with cinnamon-clove characteristic odor and taste is formed by admixing the following ingredients in the amounts shown.
TABLE 1ExemplaryIngredientSupplierWeight %Wt % RangePurified WaterCopacker91.603 80-99Glycerin USPAcme-Hardesty5.000 0.01-15HEC 250 HXHercules-Aqualon2.000 0.01-10SorbitolRoquette0.0500.001-0.5SucraloseTate & Lyle0.4000.001-1.5CetylpyridiniumDastech0.1000.001-1 ChlorideZinc GluconateAmerican Ingredients / 0.5920.001-1.5USPPharmachem Inc.Cinnamon (Oil)Berje0.2500.001-2 Clove (Oil)Berje0.0050.001-2 Red #40 (1% sol.)Pylam0.000990.000001-0.001
[0071] A clinical study comparing the composition of Example 1 to a placebo and a commercial mouth rinse including CPC was conducted. Each group started with 25 people. At the conclusion of the 6 week test period, there was an observable / measurable difference in the quality and thickness of calculus in the group using the composition ...
example 2
Reduction in GI
[0073] A clinical study comparing the composition of Example 1 to a placebo and a mouth rinse including CPC was conducted. Each group started with 25 people. At the conclusion of a six week test period, there was an observable / measurable difference in the improvement of the GI for the group using the composition of Example 1, compared to the groups using the placebo and the rinse. The difference was statistically significant (p value≦0.05, based on ANCOVA results, adjusting for baseline value and multiple comparisons) in both absolute and percent improvement of GI between the groups.
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