Nutritional composition

Abstract

A nutritional composition having a total energy content of 67 kcal / 100 ml or lower and including: a protein content which is 1.25 g / 100 ml or lower, an energy content from protein of 7.2-8.4% of the total energy content of the nutritional composition, an energy content from fat which is at least 49% or more of the total energy content of the nutritional composition, a medium chain fatty acid content comprising 8 to 10 carbons which is less than 3 wt % of total amount of fatty acids, a sialic acid content of 10-25 mg / 100 ml, a cholesterol content of 5-10 mg / 100 ml, and a sphingomyelin content of 9-15 mg / 100 ml is disclosed.

Description

FIELD OF INVENTION[0001]The present invention concerns the field of nutritional compositions and infant formulas.BACKGROUND[0002]Research has shown that birth weight and growth patterns during the first years of life are relevant to the development of the metabolic syndrome with obesity, insulin resistance, type 2 diabetes and increased risk of cardiovascular disease in adulthood (D. J. P. Barker. Hormone Research 2005; 64 (suppl. 3):2-7). According to “the growth acceleration hypothesis” a fast growth during the first year of life, probably due to imprinting effects on the metabolic system in the body, results in an increased risk to develop metabolic syndrome, type-2 diabetes and coronary heart diseases later in life. (A. Singhal et al. The Lancet, 2004, vol. 363: 1642-1645).[0003]Formula-fed infants put on weight faster during the first year of life compared to breastfed infants (J. Baird et al. Paediatric and Perinatal Epidemiology, 2008, Vol. 22, 575-586. K. G. Dewey. Biol Neon...

AI Technical Summary

Benefits of technology

[0031]Energy density: It is well known that infants fed a standard formula show a more rapid weight gain than breastfed infants. This is due to several factors: A higher protein intake, a higher caloric intake due to a higher energy density of the formula and a less developed self-regulation of caloric and volume intake. Since a part of the total carbohydrates in breast milk (the oligosaccharides) are not used as an energy source and the lactose content in infant formula earlier was regarded as the same as the total carbohydrate content in breast milk. The content of lactose in the nutritional composition according to the invention is reduced in order to reach a nutritional composition with decreased energy density (kcal / 100 ml). No one has before developed a product where both protein content and caloric content are reduced which still has all other nutrients present in desired levels. According to the present invention such a formula has been developed. The nutritional composition according to the invention has been tested in a clinical study. The growth of the infants using the nutritional composition according to the invention was similar to the growth of breastfed infants. The study thereby shows that the content of energy and amino acids was satisfactory.

[0215]The growth between the breast fed infants and the Formula A fed infants did not differ. The new nutritional composition according to the invention reduces the differences between breastfed and formula-fed infants in terms of metabolic factors, as well as neurological development.

Problems solved by technology

The challenges known to the skilled person, but not at present satisfactory taken care of are: protein content and protein quality, energy density, content of essential fatty acids, content of medium chain fatty acids (MCT), content of sialic acid, gangliosides, sphingomyelin, and the content and quality of cholesterol in the formulas out on the market today.

No one has before developed a product where both protein content and caloric content are reduced which still has all other nutrients present in desired levels.

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