Complex between lactoferrin and silica, process for the production thereof, and composition thereof for oral hygiene
a technology of complexes and silica, which is applied in the direction of silicon compounds, transferrins, animal/human proteins, etc., can solve the problems of affecting the quality of life of the organism, and loss of bone tissue and therefore of the implant itself, so as to achieve high stability and bioavailability
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Benefits of technology
Problems solved by technology
Method used
Image
Examples
examples 1-3
[0056]The compositions shown in Table 1 were prepared (% by weight of the total composition):
TABLE 1EXAMPLE123 (*)glycerol51.651.074.0water7.015.025.0hydrophilic40.030.0—silicarice husk0.43.0—silicalactoferrin1.01.0 1.0(*) comparative[0057]Hydrophilic silica: hydrophilic fumed silica having a specific surface area of about 200 m2 / g (BET area, measured according to standard ISO 9277-2010) (commercial product Aerosil™ 200 by Evonik);[0058]Rice husk silica: silica in the form of an aerogel having a specific surface area of about 550 m2 / g (BET area, measured according to standard ISO 9277-2010) and a density of about 0.050 g / cm3.
[0059]The rice husk silica and lactoferrin were previously complexed through the following process. The rice husk silica was prepared as described in Example 1 of WO 2016 / 193877, with the difference that, after obtaining the silica sol-gel, this was added to the lactoferrin and then subjected to drying with supercritical CO2 as described in the same Example 1, w...
examples 4-6
[0077]Examples 2 and 3 were repeated under the same conditions and with the same ingredients shown above (Examples 4 and 5). A further comparative example (Example 6) was also carried out, again with the same procedure and the same ingredients, wherein the lactoferrin was simply mixed with the hydrophilic silica, i.e. without preparing a complex according to the present invention, wherein silica is prepared in a sol-gel form, lactoferrin is added and then dried. The compositions are reported in Table 4 (% by weight of the total composition):
TABLE 4EXAMPLE45 (*)6 (*)glycerol51.074.051.0water15.025.015.0hydrophilic30.0—33.0silicarice husk3.0——silicalactoferrin1.0 1.0 1.0(*) comparative
[0078]Antioxidant and antibacterial properties of these compositions were verified, evaluating the variation of the efficacy over time, as described in Examples 1-3.
[0079]The results are reported in the following tables, where the left column shows the times (in minutes for Table 5 and in hours for Table...
PUM
Property | Measurement | Unit |
---|---|---|
Temperature | aaaaa | aaaaa |
Temperature | aaaaa | aaaaa |
Temperature | aaaaa | aaaaa |
Abstract
Description
Claims
Application Information
- R&D Engineer
- R&D Manager
- IP Professional
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com