12 results about "Peri-implantitis" patented technology

The invention discloses an antioxidant and antibacterial collagen repair membrane and a preparation method thereof. The repair membrane is prepared by sequentially carrying out polylysine graft modification and catechinic aldehyde and aminoglycoside antibiotic synchronous covalent grafting on a purified collagen membrane. By controlling parameters such as molecular weight and concentration of polylysine, proportion and loading capacity of functional molecules, reaction conditions and the like, accurate regulation and control of film thickness, function release rate, oxidation resistance and antibacterial performance can be realized. The invention further provides a double-layer composite membrane structure, the rapid antibacterial layer and the long-acting anti-oxidation layer are compounded, and function decoupling and time sequence collaboration are achieved. The repair membrane has excellent oxidation resistance and broad-spectrum antibacterial performance, is good in biocompatibility and adjustable in degradation rate, can be customized according to different clinical requirements, and is suitable for oral wound repair, periodontal guided tissue regeneration, bone tissue induced regeneration, peri-implantitis prevention and treatment and chronic refractory wound treatment.

The invention provides a photosensitizer / ZIF-8 nanocomposite, a preparation method and application thereof, and a pharmaceutical composition for treating periodontitis and / or peri-implantitis. The photosensitizer / ZIF-8 nano-composite is prepared by the preparation method disclosed by the invention. The preparation method comprises the following steps: dissolving zinc salt in a solvent to form a solution A; dissolving an imidazole ligand in a solvent, and adding a photosensitizer under a dark condition to form a solution B; quickly adding the solution A into the solution B under a dark condition, and stirring and reacting at room temperature; and after the reaction is completed, centrifugally separating to obtain a solid product, washing and drying. The application of the photosensitizer / ZIF-8 nano-composite comprises the application of the photosensitizer / ZIF-8 nano-composite in preparation of photodynamic antibacterial drugs. A pharmaceutical composition for treating periodontitis and / or peri-implantitis comprises the photosensitizer / ZIF-8 nano compound and an auxiliary material. The preparation method is simple, the raw materials are cheap and easy to obtain, and the obtained compound serving as the photodynamic antibacterial agent is remarkable in antibacterial effect and low in toxicity.

An intraoral device 16 for treatment of peri-implantitis has a head 20 that supports an optical engine 22. The optical engine comprises an enclosure for accommodating a dental implant in vivo and ligh

An intraoral device for treatment of peri-implantitis has a head that supports an optical engine. The optical engine comprises an enclosure for accommodating a dental implant in vivo and light emitters such as LED arrays or waveguides angularly spaced around the enclosure, configured to emit UVC light into the enclosure. One or more jaws are movable to open and close the enclosure. At least one of the light emitters is mounted on the or each jaw and at least one of the light emitters is fixed relative to a housing that supports the or each jaw. High-wavelength light sources and low-wavelength light sources are employed for photo-functionalisation of the implant and / or for sterilisation of the implant region. At least one supplementary array on an edge or end of the enclosure comprises additional low-wavelength light sources and emits light away from the enclosure for sterilisation of the implant region.

The application discloses a kind of implant piezoelectric nano coating and its preparation method and application.The nano coating is composed of nano-flower-shaped barium titanate and gold nanoparticles loaded on its surface.In this application, gold nanoparticles are deposited on nano-barium titanate at high temperature by using the method of sodium citrate reducing tetrachloroauric acid. The nBTO@Au prepared by this method has obvious osteogenesis and antibacterial properties. The application provides a high reactivity, catalytic and non-invasive immediate treatment mode for peri-implantitis, which has wide application potential in implant post-disinfection, peri-implantitis treatment and improving implant survival rate.

The application relates to the technical field of dental implants, in particular to a trans-zygomatic implant and a processing technology thereof, and the processing technology comprises variable-distance multi-stage sand blasting and acid etching surface treatment on an anchoring part with threads of the trans-zygomatic implant and electrochemical polishing surface treatment on an extension part without threads. The trans-zygomatic implant is treated by variable-distance multi-stage sand blasting combined with acid etching, so that a uniform micron-level rough base and a multi-stage micropore structure can be formed on the titanium surface, osteoblast adhesion and differentiation are facilitated, the early bone combination speed is accelerated, the combination strength is improved, the early implant loosening risk is reduced, the extension part of the trans-zygomatic implant is treated by electrochemical polishing, a smooth surface can be obtained, plaque adhesion and bacterial colonization are greatly reduced, the implant peri-implantitis risk is reduced, and soft tissue adhesion is promoted; the dual optimization of bone anchoring and tissue adhesion is realized, and the long-term function and health of the trans-zygomatic implant under complex stress are guaranteed.

The peri-implantitis treatment device (1) according to the present invention is provided with: an electrode (14) for applying a negative potential to a metal part (7) of a dental implant (8); a potential controller for controlling the potential of the electrode (14); and a mouthpiece (2) that holds the electrode (14) and the potential controller and is attached to the dental implant (8). The peri-implantitis treatment device (1) according to the present invention can effectively inactivate even bacteria (bacterial colonies) that are in a deep periodontal pocket hardly cleaned mechanically and in a state of forming a biofilm against which antibiotics are less effective.

Disclosed are a multi-point fixation two-piece root analogue implant apparatus and use thereof, which relate to the technical field of human stomatology. The apparatus comprises a root analogue implant, a transgingival collar, a fixation screw, a healing screw, a restoration screw, and a restoration abutment, wherein the root analogue implant is internally provided with a restoration fixation channel and 1-3 fixation screw channels, and all the channels are internally threaded. The occlusal surface of the upper end of the implant is provided with a fixation recess. The restoration abutment is internally provided with a V-shaped channel, and the smaller opening of the channel corresponds to the restoration fixation channel on the gingival surface of the implant. The gingival surface of the restoration abutment is provided with a fixation protrusion matched with the fixation recess. The transgingival collar is 3D printed by using zirconia and is used after the tissue surface is glazed. This solves the problem of unsightly blackening of the gums due to metal ion precipitation and oxidation at the metal transgingival portion. Furthermore, the smooth glazed surface resists bacterial adhesion, effectively preventing peri-implantitis. The technical solutions of the present invention can improve the initial stability of RAI implantation and expand the clinical indications for RAI.

An antibacterial alloy material suitable for making biomedical implants and surgical instruments and devices associated with biomedical implantation is disclosed. The alloy material comprises about 50–99.99 wt.% Ti, about 1–49 wt.% Cu, and about 0.01–10 wt.% SiO2. The antibacterial alloy material imparts antibacterial properties by enabling controlled ion release to inhibit biofilm formation, addressing issues like peri-implantitis associated with conventional bio-inert materials. In addition, the antibacterial alloy material enhances osseointegration and improves the mechanical durability of the resulting implants and surgical instruments and devices, including hardness and wear resistance. In addition, the antibacterial alloy material exhibits anti-corrosive properties and may be fabricated via techniques like spark plasma sintering (SPS).

The present disclosure provides for compositions including GlcNAc and methods of treating or preventing oral diseases, and the like. In an aspect, GlcNAc can be used as an agent in a composition to treat and / or prevent oral diseases such as dental caries (or tooth decay), oral candidiasis (or oral thrush), periodontitis, peri-mucositis and peri-implantitis. Each of these diseases is a biofilm disease with a dysbiotic etiology.