Self-film-forming composition for oral care

一种组合物、成膜的技术，应用在医学和微生物学领域，能够解决全身性预防作用有限、增加细菌等问题

Pending Publication Date: 2018-04-17
BIOTICS
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Systemic prophylaxis is limited because bacteria tend to quickly aggregate into protected clusters, increasing the likelihood of antibiotic-resistant bacteria

Method used

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  • Self-film-forming composition for oral care
  • Self-film-forming composition for oral care
  • Self-film-forming composition for oral care

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0036] The present invention provides a self-filming composition in powder form comprising lactic acid bacteria and a method for its preparation comprising mixing with a liquid medium.

[0037] In one aspect, a self-film forming composition comprises at least one gelling agent, at least one bioadhesive agent, and at least one strain of lactic acid bacteria. In another aspect, a self-film forming composition comprises at least one gelling agent or at least one bioadhesive agent and at least one Pediococcus strain.

[0038] Self-film-forming composition in powder form

[0039] The lactic acid bacteria included in the self-film-forming composition in powder form of the present invention may be in the form of living cells or non-living cells. Typically the strains are used in the form of living cells. However, it can also be extended to non-viable cells, such as killed cultures or cell lysates (obtained, for example, by exposure to altered pH, sonication, radiation, temperature...

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PUM

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Abstract

A self-film-forming composition in powder form, a reconstituted formula and a kit for oral use are provided, which allow an adequate colonization of the probiotic in the oral cavities together with asufficient residence time to allow beneficial effects against the pathogens related with oral conditions. Thus, the items provided are useful for the prevention and / or treatment of a condition relatedto alterations of the oral microbiota, and specifically for peri-implantitis. The self-film- forming composition in powder form comprises at least a gelifier agent and / or at least a bioadhesive agent, and at least one lactic acid bacteria strain.

Description

technical field [0001] The present invention relates to the fields of medicine and microbiology, in particular to compositions for dental care and treatment. In particular, the present invention includes compositions for the treatment and / or prevention of peri-implantitis and other oral conditions associated with microbial dysbiosis. Background technique [0002] Inflammatory lesions that arise in the tissues surrounding implants are collectively referred to as peri-implant disease and include two disease entities: mucositis and peri-implantitis. Peri-implantitis and peri-implant mucositis have similar signs, but crestal bone loss is absent in peri-implant mucositis. Mucositis was defined as reversible modification of peri-implant soft tissue without bone loss. Peri-implantitis inversely affects the deep soft tissue and bone surrounding the implant, and it is defined as an inflammatory process that affects tissue adjacent to an osseointegrated implant in a manner that caus...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/00A61K9/14A61K9/19
CPCA61K9/0056A61K9/146A61K9/19A61K9/0063A61P1/02A61P31/10A61P31/22A61K35/744
Inventor J·萨塔斯古特利兹E·拉扎罗梅兰J·库恩卡斯特拉纳J·M·玛丽库布诺J·L·卡尔沃圭拉多
Owner BIOTICS
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