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Bionic micro/nano antibacterial structure, manufacturing method therefor and application of bionic micro/nano antibacterial structure

A manufacturing method and nanotechnology, applied in the field of bionic medicine, can solve problems such as low drug efficacy, irreversible oxidative stress, cell or organ damage, etc.

Inactive Publication Date: 2020-10-23
SHENZHEN UNIV +1
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Problems solved by technology

[0005] In view of the deficiencies in the above-mentioned prior art, the object of the present invention is to provide a bionic micro / nano antibacterial structure and its manufacturing method and application, aiming to solve the problem that oral antibiotics are prone to produce resistance in the current method of inhibiting peri-implantitis. Low drug properties and efficacy; the use of silver particles for antibacterial can easily lead to irreversible oxidative stress, cell or organ damage, asthma and even cancer

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[0029] In order to make the object, technical solution and advantages of the present invention more clear and definite, the present invention will be further described in detail below with reference to the accompanying drawings and examples. It should be understood that the specific embodiments described here are only used to explain the present invention, not to limit the present invention.

[0030] An implant abutment is an abutment anchored on the implant platform in the bone and used to link, support and retain oral implants, also known as a transmucosal abutment. Scientists have found that after implants are placed in the oral cavity, invading bacteria accumulate on the surface of the implant abutment and the implant-bone interface to form a biofilm, causing peri-implantitis. To deal with peri-implantitis, there are mainly two clinical methods at this stage. One method is oral antibiotics. This method has a short action time and is prone to drug resistance, and the oral m...

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Abstract

The invention provides a bionic micro / nano antibacterial structure, a manufacturing method therefor and application of the bionic micro / nano antibacterial structure. The bionic micro / nano antibacterial structure is applied to an oral cavity implant and comprises an implant base station and micro / nano burs which are arranged on the implant base station and are tightly incorporated with the implantbase station. According to the bionic micro / nano antibacterial structure, the micro / nano bur structure with an antibacterial function is applied to the surface of the implant base station, so that theimplant base station can have very good antibacterial performance, bacteria surrounding an implant can be inhibited durably, and periarthritis of the implant can be eliminated or decelerated; and thebionic micro / nano antibacterial structure is harmless to human bodies.

Description

technical field [0001] The invention belongs to the technical field of bionic medicine, in particular to a bionic micro / nano antibacterial structure and its manufacturing method and application. Background technique [0002] With the development and progress of dental implant restoration, implant restoration has gradually replaced active restoration technology and has become the first choice for people to treat dentition defects or missing cases. However, with the rapid increase in the number of cases, many complications of implant restoration are gradually exposed. Among them, the most prominent one is "peri-implantitis", a complication that can directly lead to the failure of the entire implant operation. Scientists have discovered that the main cause of peri-implantitis is that after implant placement, invading bacteria accumulate on the surface of the implant abutment and the implant-bone interface to form a biofilm, which in turn causes an inflammatory response. The l...

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Application Information

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IPC IPC(8): A61C8/00A61L27/06A61L27/02A61L27/50
CPCA61C8/0012A61C8/0013A61C8/0016A61C8/0075A61C8/0093A61L27/025A61L27/06A61L27/50A61L2400/18A61L2430/12
Inventor 邓永强李歆李旭光朱耀旻
Owner SHENZHEN UNIV
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