Unlock instant, AI-driven research and patent intelligence for your innovation.

Analysis of gas samples for determination of physiological states and disease states

a technology of physiological states and gas samples, applied in the field of analysis of gas samples for determination of physiological states and disease states, can solve the problems of difficult early diagnosis of patients, risk to patients, and excessive radiation risk of mammograms, and achieve the effect of saving lives

Pending Publication Date: 2021-08-19
NEW YORK UNIV
View PDF3 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

The patent describes how different samples of biogas, such as breath, can have different responses to a sensor. These samples can also be analyzed to detect physiological states and disease states, such as cancers. By measuring the activity of certain drugs and monitoring drug compliance, this technology can help screen for health risks and potentially save lives.

Problems solved by technology

It is very hard to diagnose patients early because most of the symptoms do not appear and diagnosing procedures are costly and can sometimes pose risks to the patient.
Mammograms can expose excessive risk of radiation, risk tumors rupturing and over diagnose breast cancer.
All these methods are time consuming and may impose some risks for patients.
However, most cancer-linked symptoms are not as easily recognizable unless a thorough procedure is done, such as a biopsy.
These procedures happen to be very costly and can have negative health risks associated with it, hence they are mainly done when symptoms are more obviously present in the patient.
However, there are currently no efficient ways of correlating breath sample analysis to diseased physiological states.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Analysis of gas samples for determination of physiological states and disease states
  • Analysis of gas samples for determination of physiological states and disease states
  • Analysis of gas samples for determination of physiological states and disease states

Examples

Experimental program
Comparison scheme
Effect test

example 1

[0095]This example provides a description of methods and system of the present disclosure.

[0096]Materials. Aniline (Sigma >99%) was freshly double distilled before use. Hydrochloric acid HCl (ACS reagent), ammonium persulfate (APS), ammonium hydroxide (25%), chloroform (>99%) and camphor sulfonic acid (CSA) were purchased from Sigma and were used as received. Thin Film film interdigitated platinum film electrodes (IDA) (line spacing 100 μm) were purchased from the Electronic Design Center, Case Western University, precision gas diluter Model 1010 was purchased from Custom Sensor Solutions. A 25 ppm ammonia / dry N2 was used as the calibration standard and was purchased from Prest-O sales.

[0097]Experimental. Polyaniline (PANI) doped with HCl was prepared by chemical oxidative polymerization of aniline in aqueous acidic medium (1M HCl) with APS as an oxidant. It has been reported earlier that higher polymerization yields were obtained by using oxidant to monomer ratio of 1.2. 50 ml of 0...

example 2

[0103]This example provides a description of methods and system of the present disclosure.

[0104]FIGS. 6 through 21 shows data obtained using methods and systems of the present disclosure. The figures described show gas responses on one polyaniline sensor, an example of one sensor with three gases and three sensors on three gases, six sensors on five gases—building the MOLECULAR FRAME, measuring the scent from cancer cells, changing the frame from 5 to four gases, and various other data. See FIG. 8.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
concentrationsaaaaaaaaaa
concentrationaaaaaaaaaa
semiconductingaaaaaaaaaa
Login to View More

Abstract

Provided methods of detecting physiological states and / or disease states of an individual. Also provided are systems for detecting physiological states and / or disease states of an individual. The method are based on the response of organic semiconducting materials to one or more components of a biogas sample from an individual.

Description

CROSS REFERENCE TO RELATED APPLICATIONS[0001]This application claims priority to U.S. Provisional Application No. 62 / 975,648, filed Feb. 12, 2020, the entire disclosure of which is incorporated herein by reference.BACKGROUND OF THE DISCLOSURE[0002]The human body releases many volatile organic compounds. These compounds typically reflect the body's current metabolic condition, cells, tissues, and microbiome. The body's metabolism consists of chemical processes that are required to sustain life. Small molecules, known as metabolites, circulate in the body and are reliable biomarkers because their profiles are changed when the body's biological system is affected due to disease, mutations, or even environmental factors.[0003]Cancer is the second leading cause of death worldwide. It is very hard to diagnose patients early because most of the symptoms do not appear and diagnosing procedures are costly and can sometimes pose risks to the patient. Breast cancer typically is diagnosed throu...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(United States)
IPC IPC(8): A61B5/08G01N33/00A61B5/097
CPCA61B5/082A61B5/097G01N33/0075
Inventor LEVON, KALLECHIANG, HAO-CHUNGRIGORYEV, NIKITASCHNABL, FREYASELESNICK, IVAN
Owner NEW YORK UNIV