57 results about "Subcutaneous Infusions" patented technology

A device for inserting a subcutaneous infusion device into skin of a patient. The device can include a housing, a needle hub including a needle, a sleeve, and a spring engaging the needle hub. The device can also include a cap coupled to the housing, and a retention member configured to maintain the device in a ship state prior to decoupling of the cap from the housing. In one example, the retention member can include a boss coupled to the cap and configured to engage the infusion device to maintain the infusion device in the ship state prior to decoupling of the cap from the housing. In another example, the retention member can include a tab formed by the sleeve, the tab engaging a bead on an internal surface of the cap when the sleeve moves relative to the housing while the device is in the ship state.

An insertion device for inserting an infusion device at least partially into skin for subcutaneous infusion can comprise a sleeve having a lower surface that is configured to engage the skin, a shuttle or carriage to carry the infusion device between a retracted position and an advanced position; at least a first biasing member to urge the shuttle or carriage toward the advanced position, and an actuator to cause the first biasing member to urge the carriage from the retracted position to the advanced position. In some embodiments, the insertion device can further comprise a hub and at least a second biasing member to urge the hub away from the shuttle or carriage. In some embodiments, the insertion device can further comprise a needle attached to the hub. Methods for inserting an infusion device and various other features that can be comprised by an insertion device are also disclosed.

A subcutaneous infusion set. The subcutaneous infusion set may include a base for providing an infusion path; a cannula connected to and extending away from the base; a connector removably attachable to the base; and a tubing affixed to the connector. The connector may be limitedly rotatable on the base when the connector is removably attached to the base. Also, a contiguous pass for passing fluids may be formed from the tubing to the cannula when the connector is removably attached to the base.

An injector device for transcutaneously placing at least a portion of a cannula of a medical device through the skin of a patient is provided. The injector device includes a device housing having a bore formed therein and a plunger slidably received within the bore. The plunger includes an insertion needle secured thereto for receiving the cannula of the medical device. The insertion needle remains secured to the plunger subsequent to placement of the medical device and the insertion needle and the injector are removable from the cannula while maintaining the transcutaneous placement of the cannula.

A subcutaneous infusion device, including an infusion set and conduit, the infusion set including a cannula and a hub. The cannula may include a coil component that is helically arranged around a longitudinal axis to define a lumen and a tubing component that is associated with the coil component and may take on the shape of the outer surface thereof. The cannula may include a proximal guide to assist in the insertion of a needle therethrough. Both integral and attachable infusion set and conduit combinations are described, as well as a sterile package and insertion mechanism.

The invention provides a subcutaneous infusion device including a delivery tube having a central lumen and a closed first end and an open second end. The device further includes a support base attached adjacent a first end of the delivery tube; and a plurality of needles extending substantially perpendicular to the support base and in communication with the central lumen of the delivery tube. A method for hydrating a patient in accordance with the invention includes pressing a support base against a skin surface of the patient and inserting a plurality of needles into a subcutaneous skin layer responsive to the pressing. The method further includes delivering a saline fluid to the subcutaneous skin layer through the needles via a delivery tube.

A subcutaneous infusion set. The subcutaneous infusion set may include a base for providing an infusion path; a cannula connected to and extending away from the base; a connector removably attachable to the base; and a tubing affixed to the connector. The connector may be limitedly rotatable on the base when the connector is removably attached to the base. Also, a contiguous pass for passing fluids may be formed from the tubing to the cannula when the connector is removably attached to the base.

An infusion set preferably for use with an inserter is disclosed. The infusion set includes a septum cap that encapsulates an upper resilient septum and a lower resilient septum of a base, and includes at least one radial port to receive insertion of a blunt cannula when an extension set hub is engaged with the infusion set in a direction substantially parallel to the skin surface. The extension set hub is configured to provide a snap-fit engagement with the septum cap, wherein the blunt cannula of the extension set hub is guided through the radial port of the septum cap and penetrates the interface between the upper septum and the lower septum. The extension set hub and the septum cap can be rotated in a 360 degree manner about the base of the infusion set.

This invention relates to a packing for an injector device for the placement of a subcutaneous infusion set on a patient. An insertion needle used in conjunction with an injector device is employed for transcutaneous placement of a soft and relatively flexible tubular cannula, followed by removal of the insertion needle and subsequent infusion of medical fluid according to the present invention can storage an injector device combined with an infusion set and an insertion needle under sterile conditions. The packing comprises at least—a first storage room storing the injector device combined with an infusion set and an insertion needle, —a first part (1) providing a further storage room (9b) isolated from the insertion needle (312, 26), is constructed with a bottom part (2a, 2b) and walls (2c) standing upright form the bottom part (2a, 2b), —a second part which is attached to the first part (1) before use in such a way that the conditions inside the packing remain sterile, and seen from a sectional view through the walls (2c), the walls (2c) are forming at least two sections each formed as a partial circle with at least two centres C1 and C2 and the centres C1 and C2 are placed with a distance D between them.

A subcutaneous infusion device includes an indwelling member which has a base portion and a cannula reaching an inside of a body of a user when the base portion is fixed to a surface of the body of the user, and a coupling member which is attached to the indwelling member in a detachable / attachable manner. The coupling member includes a main body portion, a needle provided at the main body portion and communicated with the cannula when the coupling member is attached to the indwelling member, a lid portion provided turnably with respect to the main body portion, an engagement portion locking the lid portion to the main body portion, and an elastic member biased when the lid portion is locked to the main body portion and capable of biasing the lid portion in a turning direction when the locking is being released.

A system for delivering fluid to a user transcutaneously includes a subcutaneous infusion cannula base assembly, a cannula inserter assembly and a fluid connection assembly. The subcutaneous infusion cannula base assembly is configured to be located on the user's skin. The cannula inserter assembly is coupled to the cannula base assembly and is configured to drive an infusion cannula through the user's skin in a nominally helical trajectory. The fluid connection assembly is configured to fluidically connect the cannula base assembly to a source of delivery fluid. Cannula and stylet assemblies configured for helical or non-helical insertion are also disclosed.

An infusion device including a site and a set for delivery of a substance to a patient. The site can include a cannula that is introduced into a subcutaneous layer of skin of the patient. The set can be coupled to the site by placing the set over the site and moving the set from an unlocked to a locked position. The set can be oriented at multiple rotational orientations with respect to the site, and can be coupled and uncoupled with the site multiple times. Also included is a device for inserting a subcutaneous infusion device into a subcutaneous layer of skin of a patient. Some devices automatically retract a needle used to introduce the cannula. Upon full introduction of the needle and associated cannula of the subcutaneous infusion device into a subcutaneous layer of skin of a patient, the device can move the needle into a retracted state.

An infusion system having an integrated inserter and infusion set (10) for containing and placing a flexible catheter (40), and a retractable introducer needle (26), wherein the catheter (40) is isolated from movement after placement. The integrated inserter and infusion set (10) includes a hub (20), having a user push button (30) to activate the device for catheter (40) placement. An adhesive liner (34) can be provided to cover an adhesive layer (36), such as pressure sensitive adhesive (PSA), on the bottom of the device (10).

The present invention provides methods and kits for preventing, treating or delaying various cardiovascular diseases or disorders especially heart failure by extended release of neuregulin to a mammal. Moreover, the extended release of neuregulin is administered by subcutaneous infusion with a pump.

The invention provides a subcutaneous infusion device including a delivery tube having a central lumen and a closed first end and an open second end. The device further includes a support base attached adjacent a first end of the delivery tube; and a plurality of needles extending substantially perpendicular to the support base and in communication with the central lumen of the delivery tube. A method for hydrating a patient in accordance with the invention includes pressing a support base against a skin surface of the patient and inserting a plurality of needles into a subcutaneous skin layer responsive to the pressing. The method further includes delivering a saline fluid to the subcutaneous skin layer through the needles via a delivery tube.

A device for inserting a cannula of a subcutaneous infusion device into a subcutaneous layer of skin of a patient. For example, some devices automatically retract a needle used to introduce the cannula of a subcutaneous infusion device into the subcutaneous layer of skin of a patient. The device can include a housing with an internal cavity, as well as a needle coupled to the housing. The needle can be coupled to a cannula of a subcutaneous infusion device. A member can move the needle. Upon full introduction of the needle and associated cannula of the subcutaneous infusion device into a subcutaneous layer of skin of a patient, the member is automatically actuated to move the needle into the internal cavity of the housing into the retracted state while leaving the cannula of the subcutaneous infusion device in the subcutaneous layer of skin of the patient.

The present invention provides methods and kits for preventing, treating or delaying various cardiovascular diseases or disorders especially heart failure by extended release of neuregulin to a mammal. Moreover, the extended release of neuregulin is administered by subcutaneous infusion with a pump.

The invention provides a transcutaneous delivery means which includes: a shell confirming a storage device; an entrance value that can enter from the shell exterior and connects with the storage device; a transcutaneous infusion cannula that extends from the shell, flow communicates with the storage device and includes a end tip; and a skin puncture element that locates in the infusion cannula, moves between an extended position for subcutaneously inserting the distal fluid transport tube into a patient, and a retracted position.

The present invention discloses a formula and a preparation method of a coenzyme Q10 subcutaneous infusion liquid, wherein the coenzyme Q10 subcutaneous infusion liquid comprises coenzyme Q10, a solvent (vegetable oil for injection), an anti-oxidant and a preservative, and the active ingredient is coenzyme Q10. The preparation method comprises: adding coenzyme Q10 and an anti-oxidant to a heated solvent, dissolving, adding a preservative, and then carrying out volume metering, filtration, packaging, and sterilization to prepare the preparation meeting the injection requirement and suitable for subcutaneous injections. According to the present invention, the disadvantages of low bioavailability, poor stability in aqueous solution, easy precipitation, and short shelf life of the coenzyme Q10 are solved, Tween80 and other surfactants with safety hidden dangers are not used, the stability under high light is improved, the first pass effect of the oral preparation during absorption is avoided, the infusion safety risk is reduced, the cross-infection of the powder injection and the water injection is avoided, the stable blood drug level can be maintained, the related side effects can be reduced, and the clinical application level and the safety of the coenzyme Q10 are improved to the new realm.

A device for inserting a subcutaneous infusion device into skin of a patient. The device can include a housing (110), a needle hub (130) including a needle (336), a sleeve (140), and a spring (150) engaging the needle hub. The device can also include a cap (170) coupled to the housing, and a retention member (520, 540) configured to maintain the device in a ship state prior to decoupling of the cap from the housing. In one example, the retention member can include a boss coupled to the cap and configured to engage the infusion device to maintain the infusion device in the ship state prior to decoupling of the cap from the housing. In another example, the retention member can include a tab (540) formed by the sleeve, the tab engaging a bead (510) on an internal surface of the cap when the sleeve moves relative to the housing while the device is in the ship state.

This invention relates to a packing for an injector device for the placement of a subcutaneous infusion set on a patient. An insertion needle used in conjunction with an injector device is employed for transcutaneous placement of a soft and relatively flexible tubular cannula, followed by removal of the insertion needle and subsequent infusion of medical fluid to the patient through the cannula. The packing according to the present invention can storage an injector device combined with an infusion set and an insertion needle under sterile conditions. The packing comprises at least - a first storage room storing the injector device combined with an infusion set and an insertion needle, - a first part (1) providing a further storage room (9b) isolated from the insertion needle (312, 26), is constructed with a bottom part (2a, 2b) and walls (2c) standing upright form the bottom part (2a, 2b), - a second part which is attached to the first part (1) before use in such a way that the conditions inside the packing remain sterile, and seen from a sectional view through the walls (2c), the walls (2c) are forming at least two sections each formed as a partial circle with at least two centres C1 and C2 and the centres C1 and C2 are placed with a distance D between them.

A needle assembly including a needle (15, 115) having a sharpened end and an opposing end and a needle tip shield (10, 110) for shielding the needle. The needle tip shield (10, 110) includes a needle shield (20, 120) connectable to a base (80, 180) and a needle hub (40, 140) fixedly connected to the opposing end of the needle (15, 115). The needle shield (20, 120) and needle hub (40, 140) are displaceable relative to each other from a first state, in which the sharpened end of the needle (15, 115) is exposed outside the needle shield (20, 120), to a second state, in which the sharpened end of the needle (15, 115) is shielded by the needle shield (20, 120). An actuation button (70, 170) is movably connected to the needle hub (40, 140) to maintain the needle shield (20, 120) and needle hub (40, 140) in a releasable locked state in a first button position relative to the needle hub (40, 140) and to permit the needle shield (20, 120) and needle hub (40, 140) to displace relative to each other in a second button position relative to the needle hub (40, 140).

A system for delivering fluid to a user transcutaneously includes a subcutaneous infusion cannula base assembly, a cannula inserter assembly and a fluid connection assembly. The subcutaneous infusion cannula base assembly is configured to be located on the user's skin. The cannula inserter assembly is coupled to the cannula base assembly and is configured to drive an infusion cannula through the user's skin in a nominally helical trajectory. The fluid connection assembly is configured to fluidically connect the cannula base assembly to a source of delivery fluid. Cannula and stylet assemblies configured for helical or non-helical insertion are also disclosed.

A needle stick prevention device (10, 110) includes a needle shield (20, 120) for selectively covering a distal end of a needle (41, 141). A needle hub (40, 140) is movably received within the needleshield (20, 120). The needle hub (40, 140) includes a proximal end (42, 142), a distal end (46, 146), a needle (41, 141) fixedly connected to the distal end of the needle hub (40, 140), and a plurality of ribs (54) or a cylinder (150) disposed between the proximal and distal ends. An actuation button movably received in a transverse opening of the needle shield (20, 120) to engage the needle shield (20, 120), the needle hub (40, 140) and a medical device. A spring (58, 158) is disposed between the needle hub (40, 140) and actuation member to automatically retract the needle (41, 141) into theneedle shield (20, 120).

The present invention relates to a method of treating congestive heart failure (CHF) in a subject comprising administering a peptide derived from atrial natriuretic peptide (ANP) prohormone (eg vessel dilator; VSDL) or a mimetic thereof. In a particular application, the invention provides a method of treating the particular indication known as acute decompensated congestive heart failure (ADCHF). Devices for intravenous or subcutaneous infusion for use in the method of the invention are also disclosed.

The invention relates to an indwelling subcutaneous infusion apparatus capable of being repeatedly utilized. The apparatus comprises an emitter which consists of an emitting seat, an emitting barrel body, a compression spring A, a compression spring B, a steel needle, an indwelling needle and a trigger, the top of the compression spring A and the top of the compression spring B are respectively fixed at positions in the emitting barrel body, which are close to the top and the middle, the bottom of the compression spring A is fixed on a position of a steel needle pedestal, which is close to the bottom, the bottom of the compression spring B is fixed on the bottom end face of the emitting seat, a clamping table is fixed at a position of one side of the steel needle pedestal, which is close to the top, the clamping table is clamped on a fixed bulge on the inner surface of the emitting barrel body, which is close to the top, the trigger consists of a button hinged outside the emitting seat, a spring piece fixed on the inner end face of the button and a check block with an inclined plane structure, the lower surface of the steel needle pedestal is fixedly connected with the connecting seat through a detachable manner, and a connecting rod is fixed at the bottom of the connecting seat. According to the apparatus, the structural design is ingenious, the operation is simple and convenient, and the pain that a patient suffers from can be effectively relieved.

A needle stick prevention device (10, 110) includes a needle shield (20, 120) for selectively covering a distal end of a needle (41, 141). A needle hub (40, 140) is movably received within the needle shield (20, 120). The needle hub (40, 140) includes a proximal end (42, 142), a distal end (46, 146), a needle (41, 141) fixedly connected to the distal end of the needle hub (40, 140), and a plurality of ribs (54) or a cylinder (150) disposed between the proximal and distal ends. An actuation button movably received in a transverse opening of the needle shield (20, 120) to engage the needle shield (20, 120), the needle hub (40, 140) and a medical device. A spring (58, 158) is disposed between the needle hub (40, 140) and actuation member to automatically retract the needle (41, 141) into the needle shield (20, 120).

The present invention provides infusion devices and methods for subcutaneous delivery of high viscosity fluids. The devices and methods described are innovative subcutaneous infusion systems that allow for the rapid delivery of viscous therapeutic fluids while avoiding adverse side effects and promoting patient comfort. The devices and methods described are also useful for rapid delivery of high volumes of therapeutic fluids.

An infusion set preferably for use with an inserter is disclosed. The infusion set includes a septum cap that encapsulates an upper resilient septum and a lower resilient septum of a base, and includes at least one radial port to receive insertion of a blunt cannula when an extension set hub is engaged with the infusion set in a direction substantially parallel to the skin surface. The extension set hub is configured to provide a snap-fit engagement with the septum cap, wherein the blunt cannula of the extension set hub is guided through the radial port of the septum cap and penetrates the interface between the upper septum and the lower septum. The extension set hub and the septum cap can be rotated in a 360 degree manner about the base of the infusion set.