Embodiments of the present invention provide a target positioning method, device, and system, and relate to the technical field of spatial positioning. The method is applied to a positioning device in a target positioning system, and the system further includes: a base station and a label device. The method includes: using each anchor point of the base station to determine the initial positioning result of the tag device, and judging whether the initial positioning result satisfies the positioning accuracy condition; if so, determining the initial positioning result as the final positioning result of the target to be positioned; otherwise, controlling the base station Rotate, use each anchor point of the rotated base station to determine the target positioning result of the tag device, and judge whether the target positioning result meets the positioning accuracy condition; if so, determine the target positioning result as the final positioning result of the target to be positioned; otherwise, return Steps for controlling the rotation of the base station. Compared with the prior art, applying the solution provided by the embodiment of the present invention can ensure the accuracy of the positioning result when the spatial distribution of the GDOP of the base station is uneven.