2results about How to "Avoid experimental failure" patented technology

This utility model relates to the field of reagent bottle holding cylinder technology, and discloses a reagent bottle holding cylinder for a roller mixer, including a cylinder assembly, wherein the upper and lower ends of the cylinder assembly are snapped with sealing components, the inner wall of the cylinder assembly is snapped with a ring of replaceable components, and the bottom of the inner wall of the cylinder assembly is installed with a ring of stabilizing components; the replaceable components include a separator plate and a retaining ring, wherein the separator plate is placed inside the main cylinder, and the retaining ring is fixedly installed on the inner wall of the separator plate; the replaceable components allow the device to be flexibly matched to reagent bottles of different shapes, eliminating the need to replace the entire holding cylinder for a specific container, reducing equipment costs, and reducing the risk of shaking or falling off, especially during high-speed mixing, avoiding reagent spillage, contamination, or experimental failure due to container loosening; the stabilizing components help reduce displacement or vibration of the holding cylinder, preventing the overall shaking of the instrument and protecting the experimental platform and surrounding equipment.

This invention discloses a method and system for evaluating DNA storage sequencing depth based on channel simulation, addressing the problems of inaccurate predictions and limited guidance in existing uniform distribution models. The method includes: when sequencing data is available, fitting real data to obtain log-normal distribution parameters μ and σ; when sequencing data is unavailable, obtaining μ and σ through simulation modeling based on experimental parameters; and combining these parameters to calculate the decoding ratio of the coding strand in the noiseless channel and the sequencing depth boundary in the noisy channel. The system includes input, storage channel modeling, sequencing depth calculation, and output modules. The model of this invention closely reflects reality, provides accurate predictions, reduces DNA storage and retrieval costs, improves the success rate of single-sequencing decoding, and is easy to use, facilitating the practical application of the technology.