Patents
Literature
1 results about "Coding strand" patented technology
Efficacy Topic
Property
Owner
Technical Advancement
Application Domain
Technology Topic
Technology Field Word
Patent Country/Region
Patent Type
Patent Status
Application Year
Inventor
When referring to DNA transcription, the coding strand is the DNA strand whose base sequence corresponds to the base sequence of the RNA transcript produced (although with thymine replaced by uracil). It is this strand which contains codons, while the non-coding strand contains anticodons. During transcription, RNA Pol II binds to the non-coding strand, reads the anti-codons, and transcribes their sequence to synthesize an RNA transcript with complementary bases.
A Method and System for Evaluating DNA Storage Sequencing Depth Based on Channel Simulation
PendingCN122090902Afull coverageGuaranteed reliabilityDigital storageHybridisationAlgorithmChannel encoding
This invention discloses a method and system for evaluating DNA storage sequencing depth based on channel simulation, addressing the problems of inaccurate predictions and limited guidance in existing uniform distribution models. The method includes: when sequencing data is available, fitting real data to obtain log-normal distribution parameters μ and σ; when sequencing data is unavailable, obtaining μ and σ through simulation modeling based on experimental parameters; and combining these parameters to calculate the decoding ratio of the coding strand in the noiseless channel and the sequencing depth boundary in the noisy channel. The system includes input, storage channel modeling, sequencing depth calculation, and output modules. The model of this invention closely reflects reality, provides accurate predictions, reduces DNA storage and retrieval costs, improves the success rate of single-sequencing decoding, and is easy to use, facilitating the practical application of the technology.
Owner:TIANJIN UNIV SYNTHETIC BIOLOGY FRONTIER RES INST