Transdermal absorption preparation

A preparation and liquid preparation technology, applied in the field of new percutaneous absorption-promoting compositions and percutaneous absorption preparations, can solve problems such as strong skin irritation, drug effectiveness, and damage to drug stability
CN100341577CInactive Publication Date: 2007-10-10HISAMITSU PHARM CO INC
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
HISAMITSU PHARM CO INC
Publication Date
2007-10-10
Estimated Expiration
Not applicable · inactive patent

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Abstract

A transdermal absorption promotion composition comprising the following components (a), (b), and (c) and a transdermal absorption preparation comprising the following components (a), (b), (c), and (d) are disclosed. (a) propylene glycol (b) a polyol fatty acid ester (c) lauromacrogol (d) a drug component The transdermal absorption promotion composition and transdermal absorption preparation not only exhibit an excellent transdermal absorption promotion effect, but also exhibit superior skin-permeability, even if a drug having a relatively high lipophilic property and poor transdermal absorbability is used, exhibit a favorable feeling of use, and are safe and stable.
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Description

technical field

[0001] The present invention relates to a novel transdermal absorption-promoting composition and a transdermal absorption preparation, more specifically, to a transdermal absorption-promoting composition capable of promoting the transdermal absorption of a compound (drug) with relatively high lipophilic physiological activity, It also relates to a percutaneous absorption preparation containing the percutaneous absorption-promoting composition and a drug. Background technique

[0002] As the method of administration to a patient, oral administration, transdermal administration, injection administration, etc. may be used. When administered orally, the bioavailability of some drugs may be reduced due to first-pass effects in the liver, and some drugs may have adverse effects on the gastrointestinal tract. In addition, depending on the clinical state of the patient, oral administration may sometimes be difficult. On the other hand, injection administration not ...

Claims

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