71 results about "Clinical state" patented technology

A method for operating a cardiac rhythm management device in which a clinical state vector is computed as a combination of a plurality of parameters related to a patient's heart failure status and compared to a previously computed clinical state vector to determine a clinical trajectory indicative of changes in the patient's heart failure status. Such detected changes in status can be used both as a clinical tool to evaluate treatment and to automatically adjust the operation of the device.

The invention relates to the determination of the clinical state of a subject. A respective adaptive transform is applied to at least one measurement signal acquired from the subject, each adaptive transform being dependent on previously acquired history data, and a diagnostic index is formed, which is dependent on the transformed measurement signal(s) and serves as a measure of the clinical state of the subject. In order to reliably evaluate the clinical state of a subject on a fixed diagnostic scale during changes in the state of the subject, some or all of the previously acquired history data on which an adaptive transform is currently dependent is replaced with other previously acquired history data when a predetermined event is detected. The predetermined event is indicative of a change in the respective measurement signal, and the introduction of the said other previously acquired history data sets the transform ready for the change.

The invention relates to the determination of a diagnostic index indicative of the clinical state, especially nociceptive state, of a subject. In order to improve the quality of the determination process, desired input signals derived from the subject are monitored and the quality of the process is improved based on the monitoring. This is implemented by increasing user awareness of the reliability of the index or by controlling the measurement set-up. Quality information indicative of the reliability of the current index values may be produced based on the input signals. The quality information may then be employed to give an indication of the current reliability of the index and a warning if the reliability of the diagnostic index becomes compromised.

The invention relates to a method and apparatus for monitoring a patient during drug administration. In the monitoring process, at least one state index indicative of the clinical state of the patient is determined based on physiological signal data obtained from the patient. In order to eliminate inconsistencies caused by varying drug combinations in the at least one state index, drug administration data is maintained, which identifies the drug(s) administered to the patient, and the determination of the at least one state index is controlled in dependence on the drug administration data, thereby to produce values for the at least one state index, which remain substantially consistent regardless of the particular combination of the drugs administered to the patient.

A system and method for displaying a patient clinical status indicator. In one embodiment the system includes a plurality of sensors, each sensor measuring a respective patient parameter; a processor in communication with each of the plurality of sensors, and a display in communication with the processor. The processor receives the patient parameters and generates a patient clinical status indicator in response to the plurality of patient parameters. The display displays the patient clinical status indicator. In one embodiment the patient clinical status indicator is a risk indicator. In one embodiment, the method includes the steps of measuring a plurality of patient parameters; generating a patient clinical status indicator in response to the plurality of patient parameters; and displaying the patient clinical status indicator. In another embodiment the step of generating the patient clinical status indicator further uses a plurality of weighing coefficients each associated with a respective patient parameter.

There is provided a method for predicting a clinical state of a subject based on image data obtained from a Volume Of Interest in the subject. The method comprise the establishment of a predictive model that relates image features and the future evolution of a clinical state.

A healthcare tool allows a patient to record daily parameters associated with the patient's clinical status, for example, body weight for congestive heart failure patients. A graph may be created showing the parameters on a control chart. The parameters are statistically analyzed against a control range, and when a parameter moves out of the control range, the system automatically creates a pop-up window alerting the patient that the parameter is outside the control range, and that the patient should consider informing a healthcare professional.

A method of translating clinical information into one or more standardised systems of coding or nomenclature processes received clinical information (202) relating to a patient, which includes at least one free text description of a clinical status of the patient. The free text description is analysed (208-218) to identify one or more terms relevant to the clinical status of the patient. One or more translation sets are constructed (220), each of which includes one or more sequential identified terms. Each translation set is translated (234-252) into one or more standardised health codes or terms selected from a predetermined system of classification and/or nomenclature, and the selected standardised health codes or terms are output (254). The method may be computer-implemented, either as a standalone program, or in a networked configuration supporting access from remote terminals.

Disclosed embodiments include a telemedicine communication system designed to make possible “virtual” patient visits by approved visitors such as the spouse, family, and friends of the hospitalized patient having the appropriate digital certificate and visitation/communication permissions. According to one embodiment, the system enables relatives to visit hospitalized patients using audiovisual communication modalities selected according to the severity and health status of the patient. Additionally, the system provides functionality to enable approved relatives to follow the health status of the patient according to their permissions.

Methods for screening or diagnosing subjects for disorders involving accumulation of one or more oxysterols such as cytotoxic oxysterol accumulation, Niemann-Pick C(NPC) disease, lysosomal storage diseases, cholesterol trafficking diseases, and neurodegenerative diseases. Also provided are methods for methods for screening or diagnosing subjects (including infants and neonatal subjects) for NPC disease, methods for monitoring the progression, remission, and clinical status of NPC disease, and methods for evaluating the efficacy of therapeutic treatment of NPC disease.

The invention provides methods for assessing the clinical status of a patient. In particular, the invention provides methods for identifying the presence of or likelihood of disease or disease recurrence. In practice, methods of the invention provide the ability to screen patients into one of three distinct clinical categories. Based upon measurement of clinically-relevant biomarkers in a sample obtained from a patient, the invention allows the unambiguous identification of patients who are not at risk for or do not have the relevant disease, the unambiguous identification of patients at increased risk or who have the disease; and the identification of patients who should receive standard of care treatment and/or monitoring. Use of the invention maximizes the number of patients who will receive accelerated intervention or monitoring and minimizes those patients who will receive unnecessary standard of care or accelerated intervention or monitoring.

The present invention relates to methods and apparatus for the repair of blood vessels, using a novel prosthetic graft within the blood vessels. The more concrete, the present invention relates to devices and methods for delivering and stapling endovascular grafts to the blood vessel wall. A subject of the present invention is a system and method for delivering and anchoring a graft of individual dimensions within a recipient's blood vessel. This system comprises: a) a graft configured as a tube from biologically compatible material the individual dimensions whereof, such as the diameter and length are defined by clinical state of the recipient and results of angiographic dimensions of its operated blood vessel, and b) a set of assembly units for assembling on its basis at least one device for delivering a graft and simultaneously securing this graft at both its ends to the blood vessel wall. The suggested set of assembly units includes: at least one proximal head and at least one distal head which serve to hold the graft in the process of its delivery within the blood vessel, and for securing its proximal and distal end to the wall of an operated blood vessel. The proximal and distal heads have a through axial hole with an actuator therein, as well as means for holding a corresponding graft end and means for securing this graft end to the blood vessel wall. Besides, the suggested set of assembly units includes at least one intermediate tube, at least one control means, at least one additional hold-down element, and at least one flexible control element.

A patient monitoring system includes monitoring service that receives parameter values from a number of data sources. A status model manager facilitates creation of a clinical status model that includes conditions defining relationships between parameters and thresholds. The status model manager evaluates the clinical status model based on the parameter values to determine a clinical status of a patient.

An feeding tube and a kit for installation of a feeding tube includes a balloon anchored gastric tube. A protective sleeve on a dilator protects the toroidal balloon from damage during surgical insertion of the feeding tube. In one example, a jejunal tube is integrated with the kit and the gastric tube serves as a gastric sleeve forming an annular region or channels for fluid flow to and/or from the stomach and to/from the jejunum. An integrated gastro jejunal feeding tube unit may include a jejunal tube outlet port at one end, a jejunal balloon port, a gastric sleeve outlet port, one or more gastric balloon ports, one or more gastric balloons, gastric drainage holes, a jejunal balloon positioned at end of the jejunal tube and sleeve. A black silk loop may affix an end of the jejunal tube at a position in the jejunum, and insertion of the jejunal tube may be monitored continuously using an endoscope. Drainage holes may be provided in the jejunal tube and/or the gastric sleeve. Depending on the clinical state, feeding may be initiated through the gastric sleeve outlet port or via the jejunal tube outlet port and may be altered without surgical intervention, as required. Drainage holes in the gastric sleeve may be used to deflate the stomach, while nutrition is provided by a jejunal tube inserted in the jejunum, simultaneously.

An airway device is provided that may track the flow of respiratory gases through the device with sensing elements at a plurality of locations along the gas flow path of the device. Such a device may be useful for assessing a variety of clinical states, for adjusting patient ventilator settings, or for determining whether or not an airway device has been properly inserted into a patient airway.