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Hepatitis virus resistant Chinese medicinal formulation and method for preparing same

A technology of anti-hepatitis virus and traditional Chinese medicine preparations, which is applied in the direction of antiviral agents, pharmaceutical formulas, medical preparations containing active ingredients, etc., to achieve the effect of low toxicity

Inactive Publication Date: 2008-05-21
北京百世利康医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The above drugs play a very important role in the treatment of hepatitis, accounting for more than 60% of the liver disease drug market, but they are all mainly symptomatic treatment, and there are very few anti-hepatitis traditional Chinese medicines that are really antiviral or have better curative effects

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0077] The composition of the crude drug of the present invention is: 3000 grams of Phyllostachys flavescens, 1000 grams of Sophora flavescens, 1000 grams of licorice, and 40 grams of total saponins from stems and leaves of ginseng.

[0078] (1) Take the prescription amount of Phyllostachys phylloxera, Sophora flavescens, and licorice, add water to decoct once, 0.8 hours each time, combine the decoction, filter, and concentrate the filtrate into a clear paste with a relative density of 1.05 at 60°C, add ethanol to make The alcohol content is 50%, stir well, let it stand overnight, filter out the precipitate, recover ethanol from the filtrate and concentrate it into a clear paste with a relative density of 1..05 at 60°C, add ethanol to make the alcohol content 70%, Stir well, stand overnight, take the supernatant and concentrate it into a thick paste with a relative density of 1.30 at 60°C, vacuum dry, pulverize into fine powder, and sieve to obtain the extract.

[0079] (2) pr...

Embodiment 2

[0089] The composition of the crude drug of the present invention is: 4000 grams of Phyllostachys flavescens, 2000 grams of Sophora flavescens, 2000 grams of licorice, and 60 grams of total saponins from ginseng stems and leaves.

[0090] (1) Take the prescription amount of Phyllostachys phylloxera, Sophora flavescens, and licorice, add water and decoct 3 times, 1.5 hours each time, combine the decoction, filter, and concentrate the filtrate into a clear paste with a relative density of 1.15 at 60°C, add ethanol to make The alcohol content is 70%, stir well, let it stand overnight, filter out the precipitate, recover ethanol from the filtrate and concentrate it into a clear paste with a relative density of 1.15 at 60°C, add ethanol to make the alcohol content 90%, fully stir, After standing overnight, the supernatant was concentrated into a thick paste with a relative density of 1.35 at 60°C, dried in vacuum, crushed into fine powder, and sieved to obtain the extract.

[0091]...

Embodiment 3

[0101] The composition of the crude drug of the present invention is: 3500 grams of Phyllostachys flavescens, 1500 grams of Sophora flavescens, 1500 grams of Radix Glycyrrhizae, and 50 grams of total saponins from stems and leaves of ginseng.

[0102] (1) Take the prescription amount of Phyllostachys phylloxera, Sophora flavescens, and licorice, add water to decoct twice, 1.2 hours each time, combine the decoction, filter, and concentrate the filtrate into a clear paste with a relative density of 1.08 at 60°C, add ethanol to make The alcohol content is 60%, stir well, let it stand overnight, filter out the precipitate, recover ethanol from the filtrate and concentrate it into a clear paste with a relative density of 1..08 at 60°C, add ethanol to make the alcohol content 80%, Stir well, stand overnight, take the supernatant and concentrate it into a thick paste with a relative density of 1.33 at 60°C, dry it in vacuum, grind it into a fine powder, and sieve it to obtain the extr...

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PUM

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Abstract

The invention relates to a hepatitis viruse-resisting Chinese medicinal composition and process for preparation, which is prepared from Chinese herbal extract including blattbulume, flavescent sophora root, licorice root as well as ginseng leaves saponins and medicinal auxiliary materials. The preparation can be made into various oral forms including tablet, capsule, granule, soft capsule, drop pill, oral liquid, slow release tablet and slow release capsule.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine pharmacy, and in particular relates to an anti-hepatitis virus traditional Chinese medicine preparation and a preparation method thereof. Background technique [0002] Chronic viral hepatitis is a clinical common disease, frequently-occurring disease. According to reports, the average annual incidence of viral hepatitis in my country is about 120 / 100,000, ranking third among legally notifiable infectious diseases. There are more than 100 million hepatitis B virus surface antigen (HBsAg)-positive people in my country, among which HeAg-positive people account for 27.7%, which has stronger infectivity. There are more than 2.2 million chronic hepatitis patients in my country, and about 300,000 people die each year due to liver diseases. Most of the cirrhosis and liver cancer are related to hepatitis B or C virus infection. long, easy to repeat and chronic, closely related to live...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/484A61P1/16A61P31/14
Inventor 易小平
Owner 北京百世利康医药科技有限公司