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Chinese medicine tablet of total coumarins extract from peucedanum praeruptorm and its preparing method and use

The technology of Baihuaqianhu and total coumarin is applied in the directions of pharmaceutical formulations, drug combinations, plant raw materials, etc., which can solve the problems of slow action and difficult quality control, and achieves less toxic and side effects, strong efficacy and high product purity. Effect

Active Publication Date: 2009-07-15
LUNAN HOPE PHARM CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But the main problem that exists at present is that it plays a role slowly, and the quality is difficult to control, etc., so the use of the drug is also subject to certain limitations.

Method used

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  • Chinese medicine tablet of total coumarins extract from peucedanum praeruptorm and its preparing method and use
  • Chinese medicine tablet of total coumarins extract from peucedanum praeruptorm and its preparing method and use
  • Chinese medicine tablet of total coumarins extract from peucedanum praeruptorm and its preparing method and use

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0165] Total coumarin extract of Peucedanum baicalensis 55 parts

[0166] Mannitol 150 parts

[0167] Sucrose 15g

[0168] Sodium carboxymethyl starch (add first) 20 parts

[0169] (Add later) 10 copies

[0170] Microcrystalline cellulose 100 parts

[0171] Sodium lauryl sulfate (add first) 3 parts

[0172] (Add later) 3 copies

[0173] 5% starch slurry appropriate amount

Embodiment 2

[0175] Total coumarin extract of Peucedanum radix 40 parts

[0176] Mannitol 120 parts

[0177] Sucrose 15g

[0178] Sodium carboxymethyl starch (add first) 20 parts

[0179] (Add later) 10 copies

[0180] Microcrystalline cellulose 80 parts

[0181] Sodium lauryl sulfate (add first) 1 part

[0182] (Add later) 1 copy

[0183] 5% starch slurry appropriate amount

Embodiment 3

[0185] Total coumarin extract of Peucedanum baicalensis 55 parts

[0186] Mannitol 130 parts

[0187] Sucrose 15g

[0188] Sodium carboxymethyl starch (add first) 18 parts

[0189] (Add later) 9 copies

[0190] Microcrystalline cellulose 100 parts

[0191] Sodium lauryl sulfate (add first) 3 parts

[0192] (Add later) 3 copies

[0193] 5% starch slurry appropriate amount

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Abstract

The present invention relates to a tablet of total coumarin extract of Radix Paeoniae Alba, its preparation method, and its application in the preparation of medicine for treating hypertension. After long-term groping research, the present invention confirms the effective parts of Radix Paeoniae Alba for treating hypertension, and extracts and separates the total coumarin extract of Radix Paeoniae Alba for the treatment of hypertension. The invention solves the long-standing limitations of using traditional Chinese medicines such as slow exertion and difficult quality control. In-depth systematic research on the pharmacodynamics and pharmacology of the medicine of the invention shows that the medicine of the invention has strong medicinal effect and small toxic and side effects. It has the advantages of wide safety range, high product purity, small dosage, controllable quality and the like, and through the selection of pharmaceutical excipients, the active ingredients of the medicine of the present invention have good dissolution rate and good disintegration.

Description

technical field [0001] The invention relates to a traditional Chinese medicine extract tablet, its preparation method and application thereof, in particular to a traditional Chinese medicine tablet of Peucedanum radix total coumarin extract, its preparation method, and its application in the preparation of medicines for treating hypertension. Background technique [0002] Hypertension is the chronic disease with the highest incidence rate in the world today, and it is also one of the diseases with the highest mortality and disability rates. In China, 120 people die from various cardiovascular and cerebrovascular diseases caused by high blood pressure every hour, and 600 people become disabled due to high blood pressure every hour. It seriously endangers human health and affects the quality of life. The clinical manifestations are headache, dizziness, dizziness, neck tension, tinnitus, vertigo, forgetfulness, insomnia, boredom, fatigue, numbness of limbs, palpitations, etc. ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/31A61K31/37A61P9/12A61K125/00
Inventor 赵志全
Owner LUNAN HOPE PHARM CO LTD