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Slow release type remote controlled electronic capsule

An electronic capsule and sustained-release technology, applied in the field of sustained-release remote control electronic capsules, can solve the problems of easy side effects, increase blood drug concentration, etc., and achieve the effects of good practicability, stable drug concentration, and simple structure

Inactive Publication Date: 2007-07-18
CHONGQING UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In Chinese patents CN200410040809.3 and ZL02128141.6, the schemes of remote control electronic capsules are disclosed, but the above schemes can only quickly release the medicine into the digestive tract at one time. The problem with this way of releasing medicine is that: Sexually release the drug into the digestive tract, the drug is quickly absorbed, and it is easy to form a drug absorption peak. This sudden increase in blood drug concentration is prone to side effects. To obtain a good therapeutic effect, a sustained and relatively stable drug release rate is very important

Method used

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  • Slow release type remote controlled electronic capsule
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  • Slow release type remote controlled electronic capsule

Examples

Experimental program
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Embodiment 1

[0032] The sustained-release remote control electronic capsule of the present embodiment comprises a capsule shell 1 and a remote control drive mechanism 2. One end of the capsule shell 1 has a circular through hole 5, the diameter of the through hole 5 is 3 mm, and the length of the through hole 5 is 2 mm. , a sealing plug 6 is plugged in the through hole, and the sealing plug 6 and the wall of the through hole 5 form an airtight fit. Capsule drug release channel mechanism. The capsule shell 1 is made of polycarbonate with good biocompatibility, and the sealing plug 6 is made of silicone rubber with good biocompatibility.

[0033] The sustained release type remote control electronic capsule in the present embodiment comprises a solid drug core 3, the drug core 3 is a cylinder with a diameter of 8mm, the drug core 3 has included the drug to be released, and the surface of one end of the drug core 3 has A protruding mechanism 4, which is made of water-soluble material or the s...

Embodiment 2

[0042] The main structure of this embodiment is the same as that of Embodiment 1, and the difference is that there are two circular through holes 5 at one end of the capsule shell 1, the diameter of the through holes 5 is 2 mm, and the length of the through holes 5 is 2 mm. Sealing plugs 6 are respectively plugged in the through holes 5, and the sealing plugs 6 and the walls of the through holes 5 form an airtight fit. Drug release channel mechanism of sustained-release remote control electronic capsule. The surface of one end of the drug tablet core 3 in this embodiment has two protruding mechanisms 4, and the protruding mechanisms 4 are made of water-soluble material or the same material as the drug tablet core, and the largest part of the protruding mechanism 4 is The diameter is 1.5 mm, facing directly to the two through holes 5 respectively.

[0043] Fig. 6 shows a schematic structural diagram of the slow-release remote control electronic capsule of this embodiment.

Embodiment 3

[0045] The slow-release remote control electronic capsule of the present embodiment comprises a capsule shell 1 and a remote control drive mechanism 2. One end of the capsule shell 1 has a circular through hole 5, the diameter of the through hole 5 is 4 mm, and the length of the through hole 5 is 3 mm. , the inner surface of the through hole 5 is fixed with a sealing film 15 with a thickness of 0.2mm, the sealing film 15 forms a closed fit with the through hole 5, and the sealing film 15 and the through hole 5 constitute the drug release channel mechanism of the slow-release remote control electronic capsule. The capsule shell 1 is made of polycarbonate with good biocompatibility, and the sealing film 15 is a silicone rubber film with good elasticity.

[0046] The sustained-release type remote control electronic capsule in the present embodiment comprises a solid drug core 3, the drug core 3 is a cylinder with a diameter of 8mm, the drug core 3 has included the drug to be relea...

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Abstract

A remotely controlled slow-releasing electronic capsule for releasing medicine, food or making substance in digestive tract is composed of casing, remotely controlled driver, slow-releasing channel of medicine and a medicine tablet core with a conic or cylindrical boss at its one end. Under the drive of said driver, said boss on medicine tablet can move forward to open the medicine releasing channel for slowly releasing the medicine.

Description

Technical field: [0001] The invention relates to a slow-release remote-controlled electronic capsule, in particular to a device for releasing medicine into the digestive tract, which is used to remotely and slowly release substances, such as medicine, food, markers, etc., in the digestive tract of animals or humans. Background technique: [0002] Remote control electronic capsule is a drug release system based on micro-mechanical electronic technology. It can control the release time and location of drugs in the digestive tract through external remote control. It has good application value in clinical treatment and drug absorption research in the digestive tract. In Chinese patents CN200410040809.3 and ZL02128141.6, the schemes of remote control electronic capsules are disclosed, but the above schemes can only quickly release the medicine into the digestive tract at one time. The problem with this way of releasing medicine is that: Sexually release the drug into the digestiv...

Claims

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Application Information

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IPC IPC(8): A61M31/00A61D7/00A61B5/06A61K9/48A61K9/51
CPCA61M31/002
Inventor 皮喜田刘洪英陈锋郑小林温志渝彭承琳
Owner CHONGQING UNIV
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