Refined yinqiao detoxication dropping pill
A dripping pill and Yinqiao technology, applied in the field of medicine, can solve the problems of bioavailability of liver and intestine first-pass effect, increase in the cost of medication for patients, physical damage to staff, etc. The effect of low utilization and labor intensity
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specific Embodiment approach
[0084] The specific embodiment A specific example of realizing the present invention is as follows:
[0085] Take the raw materials according to the following weight ratio:
[0086] Acetaminophen 36g Platycodon 60g Forsythia 100g Tempeh 50g Bamboo leaves 40g Licorice 50g Honeysuckle 100g Burdock 60g Ears of Nepeta 40g Menthol 0.3g
[0087] Preparation:
[0088] (1) Ten flavors in the prescription, volatile oil extracted from the ears of Nepeta: acetaminophen and menthol are crushed into fine powder; the remaining Qiwei is extracted twice with water, the first time is 2 hours, the second time is 1 hour, and the water temperature for each extraction is 98 -102°C, filter the extract, combine the filtrates, concentrate the filtrate to a relative density of 1.17, add ethanol, let it stand for precipitation, take the supernatant, recover the ethanol, concentrate it into a thick paste, dry it, and pulverize it into a dry paste powder ( 100 mesh fine powder); spare.
[0089] (2) Ta...
example 1
[0092] Example 1 Selecting different substrates for the experiment of formulating
[0093] experimental design
[0094] In order to observe the influence of the pharmaceutical active ingredient and different substrates on the products involved in the formulation of the prescription, polyethylene glycol 2000 (molecular weight is 2000), polyethylene glycol 4000 (molecular weight is 4000), polyethylene glycol 6000 (molecular weight) respectively 6000), polyethylene glycol 8000 (molecular weight is 8000) and other substrates are uniformly mixed with the active ingredients of the drug in a ratio of 1:2, and the others are all in accordance with the conditions given in the [specific embodiment], that is, the auxiliary material polyethylene glycol Heating to melt, adding the active ingredients of the drug nepeta panicle oil, dry ointment powder, acetaminophen, and menthol fine powder, and mixing evenly to obtain a drug solution to be dripped. Adjust the temperature control device of...
example 2
[0096] Example 2 Experiments of different ratios of pharmaceutical active ingredients and substrates
[0097] experimental design
[0098] In order to observe the influence of the different proportioning ratios of the active ingredients of the drug and the substrate on the products involved in the present invention, polyethylene glycol 4000 (molecular weight is 4000) is selected as the substrate, and the drug is mixed with the ratio of (1:1)-(1:8) respectively. The active ingredient is uniformly mixed with the selected matrix, and the other conditions are given in [Detailed Embodiment], that is, the auxiliary material polyethylene glycol is heated to melt, and the active ingredient Nepeta ear oil, dry paste powder and acetaminophen are added. , Menthol fine powder, mix uniformly, obtain the medicinal liquid to be dripped. Adjust the temperature control device of the dropping pill machine so that the temperature of the dropping head of the dropping pill machine is heated and k...
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