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Gynaecologic menstruation regulating preparation for treating gynecopathy and its preparation method and detection method
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A technology for regulating menstruation and gynecological diseases in gynecology, applied in the direction of diseases, testing pharmaceutical preparations, medical preparations containing active ingredients, etc.
Active Publication Date: 2010-08-25
GUIZHOU YIBAI WOMAN BIG PHARMA FACTORY
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[0003] The purpose of the present invention is to: provide a gynecological menstruation regulating preparation for treating gynecological diseases and its preparation method; the present invention provides micropills and dispersible tablets with good disintegration and high bioavailability, especially suitable for the elderly People and patients who have difficulty swallowing tablets or capsules can take it; the soft capsule preparation provided by the invention is formed by sealing the medicine in a soft rubber shell, which solves the problem of the medicine being unstable when exposed to heat and humidity, and can also cover up the bad taste and smell of the medicine , can play the role of increasing stability and improving bioavailability; the dropping pills provided by the invention have good mouthfeel, fast absorption, high bioavailability, and are convenient to take
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experiment example 1
[0039] Experimental example 1: Research on extraction and other processes
[0040] 1.1 Extraction process
[0041] In the prior art, some medicinal materials are extracted by water, but the amount of water added is not clear. Therefore, a single factor test method is adopted, and the content of paeoniflorin is used as an investigation index for optimization. The test method and results are as follows:
[0042] Weigh 32g of Angelica sinensis, 3.6g of Rhizoma Chuanxiong, 88.9g of Rhizoma Cyperi, 5.1g of Atractylodes macrocephala, 2.6g of Radix Paeoniae Alba, 2.6g of Radix Paeoniae Rubra, 7.1g of CorydalisCorydalis, 10.7g of Rehmannia glutinosa, 17.8g of Jujube, 2.4g of Radix Glycyrrhiza, 6 points in total, Add water and decoct twice, the first time for 3 hours, the second time for 2 hours, combine the decoction, filter, the filtrate is concentrated under reduced pressure, dry, weigh the paste, and measure the content of paeoniflorin in the extract, the test results See table b...
experiment example 2
[0066] Experimental Example 2: Research on Molding Process
[0067] 2.1 Dispersible tablets
[0068] The dispersible tablet can be rapidly disintegrated in water to form a uniform viscous suspension water dispersible tablet, which solves the disadvantages of poor disintegration and slow dissolution of the original dosage form. Disintegration, good suspension, high bioavailability, uniformity of dispersion.
[0078] Using the rotating basket method, lifting disintegration apparatus, take 6 tablets, and observe the situation of passing through the sieve. The higher the pass rate, the better the disintegration, which is more suitable for human body a...
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Abstract
The invention relates to a pharmaceutical preparation for treating gynaecologic diseases and regulating menstruation, its preparing process and quality control method, wherein the preparation is made mainly from Chinese angelica root, Ligusticum wallichii, prepared nutgrass flatsedge rhizome, white atractylodes rhizome, root of herbaceous peony and red peony root, and can be made into dispersibletablets, mini-pills, dripping pills, soft capsules and pharmacologically allowable dose forms. The invention also provides the method for determining and identifying contents of the preparation.
Description
technical field [0001] The invention relates to a gynecological menstrual regulating preparation for treating gynecological diseases, a preparation method and a quality control method thereof, and belongs to the technical field of traditional Chinese medicines. technical background [0002] Gynecological diseases such as irregular menstruation and abdominal painduring menstruation are common diseases that threaten women's physical and mental health in the world today, bringing great pain to women. In order to achieve the purpose of prevention and treatment, many inventors and pharmaceutical companies have done a lot of research , also provides some treatment products; such as: Fuke Tiaojing Granules, but the dosage of granules is large, the amount of auxiliary materials is large, easy to absorb moisture, and the product quality is unstable. Moreover, the variety of dosage forms is not rich enough, the scope of applicable population is narrow, the bioavailability and drug st...
Claims
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Application Information
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