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Product of Nano disperseion of water-soluble lycopene

A nano-dispersion and lycopene technology, which is applied in the field of natural pigment application, can solve the problems of insufficient particle crushing, impact on biological value, large particle size, etc., and achieve the effect of solving the problem of dissolution and increasing biological value

Inactive Publication Date: 2007-12-26
JIANGNAN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, because lycopene has strong hydrophobicity and is almost insoluble in water, many difficulties have been encountered in the actual use process.
Although people have also tried to improve the storage stability of the product and improve its water solubility by means of microencapsulation treatment, but due to insufficient crushing of the particles, the particle size is too large, resulting in the dissolution of the microcapsule wall material during use. Finally, lycopene itself cannot be stably dispersed in the system but will quickly settle to the bottom and cannot form a uniform and stable dispersion system in the matrix, so the treatment effect is not ideal; In the production of functional food (health products), although we can use soft capsules or make tablets to avoid the problem of uneven dispersion, because the particles are larger than microencapsulated products, it is difficult to take them directly Afterwards, a large part of it will not be absorbed by the human body and play a role, and its biological value will be affected accordingly

Method used

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  • Product of Nano disperseion of water-soluble lycopene

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0014] Preparation of lycopene organic solution (organic phase): take lycopene oleoresin with lycopene content of 1% (W / W), use acetone as solvent, prepare lycopene content as 0.01% (W / V) The solution is called the organic phase.

[0015] Aqueous solution of emulsifier (water phase): Tween 20 is selected as an emulsifier, and formulated into an aqueous solution of emulsifier at a dose of 0.5% (W / V), which is called the aqueous phase.

[0016] Mixing of organic phase and water phase: under low-speed stirring (100r / min), slowly pour the organic phase into the water phase, the ratio of the organic phase to the water phase is controlled at 1:9 (V / V), and continue at a high speed (800r / min). / min) and stirred for 10 minutes to make the mixture uniform.

[0017] High-speed emulsification: the obtained mixed solution was emulsified for 20 min at a rotational speed of 8000 r / min to obtain a coarse emulsion.

[0018] Nano treatment: homogenize the coarse emulsion under a pressure of ...

Embodiment 2

[0021] The preparation of lycopene organic solution (organic phase): take the purified lycopene with lycopene content of 20% (W / W), use sherwood oil as solvent, prepare lycopene content as 0.5% (W / W) The solution of V) is called the organic phase.

[0022] The aqueous solution (water phase) of emulsifying agent: choose Tween 60 and 1: 1 (W / W) of molecularly distilled monoglyceride as emulsifying agent, press the dosage of 0.5% (W / V), be mixed with the aqueous solution of emulsifying agent, called the aqueous phase.

[0023] Mixing of organic phase and water phase: under low-speed stirring (150r / min), slowly pour the organic phase into the water phase, the ratio of the organic phase to the water phase is controlled at 2:8 (V / V), continue to high-speed (900r / min) / min) and stirred for 20min to make the mixture uniform.

[0024] High-speed emulsification: the obtained mixed solution was emulsified for 10 min at a rotational speed of 10000 r / min to obtain a coarse emulsion.

[...

Embodiment 3

[0028] The preparation of lycopene organic solution (organic phase): take the purified lycopene with lycopene content of 90% (W / W), use chloroform as solvent, prepare lycopene content as 1% (W / V) ) is called the organic phase.

[0029] Aqueous solution of emulsifier (water phase): Span 20 is selected as an emulsifier, and formulated into an aqueous solution of emulsifier at a dosage of 0.5% (W / V), which is called the aqueous phase.

[0030] Mixing of organic phase and water phase: under low-speed stirring (200r / min), slowly pour the organic phase into the water phase, the ratio of the organic phase to the water phase is controlled at 3:7 (V / V), continue to high speed (1000r / min) / min) and stirred for 30min to make the mixture uniform.

[0031] High-speed emulsification: the obtained mixed solution was emulsified for 2 min at a rotational speed of 15000 r / min to obtain a coarse emulsion.

[0032] Nano treatment: the coarse emulsion is treated under 22KHz ultrasonic conditions...

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Abstract

This invention discloses a method for preparing water-soluble lycopene nanoscale dispersion product. The method comprises: dissolving lycopene or its oleoresin in an organic solvent, mixing the organic phase with an aqueous phase dissolved with an appropriate emusilfier, breaking lycopene into nanoscale by ultrahigh pressure homogenization or ultrasonic breakage, and vacuum-distilling the organic solvent to obtain uniform and stable water-soluble lycopene nanoscale dispersion (50-500 nm). The water-soluble lycopene nanoscale dispersion product can be added into water-based foods at any ratio, which solves the problem of lycopene dissolution in water-based foods. Besides, the nanoscale lycopene particles can easily infiltrate into human cells, which can increase the biological value of lycopene.

Description

technical field [0001] A water-soluble lycopene nano-dispersion product and a preparation method thereof belong to the technical field of natural pigment applications. Background technique [0002] Lycopene is a natural edible pigment and has a wide range of physiological activities. It mainly has various biological functions such as quenching singlet oxygen and scavenging peroxide free radicals, inducing intercellular communication, regulating tumor cell proliferation, and reducing the risk of cardiovascular diseases. effect. However, because lycopene has strong hydrophobicity and is almost insoluble in water, many difficulties have been encountered in the actual use process. Although people have also tried to improve the storage stability of the product and improve its water solubility by means of microencapsulation treatment, but due to insufficient crushing of the particles, the particle size is too large, resulting in the dissolution of the microcapsule wall material d...

Claims

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Application Information

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IPC IPC(8): C09B61/00C09B67/10
Inventor 张连富孙莹张胜文
Owner JIANGNAN UNIV
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