Use of bupleurum root total polyoses in the preparing of medicine for preventing and treating acute respiratory distress syndrome

Abstract

The invention belong to Chinese traditional medicine field, relates to the application of bupleurum root polysaccharide for preparing medicine preventing and treating acute respiratory distress syndrome. The invention separates polysaccharide extract from bupleurum root, the average productivity is 3.32%, and the polysaccharide content is more than 68.2%-78.6%. It is showed by whole animal model test that the protective effect for lung injury caused by acute respiratory distress syndrome is distinctive, and it is proven that polysaccharide can prevent acute respiratory distress syndrome. The bupleurum root polysaccharide can also be used to produce medicine preventing and treating fowl influenza.

Description

technical field

[0001] The invention belongs to the field of traditional Chinese medicine, and relates to a new medical application of total polysaccharide of Bupleurum bupleuri. It specifically relates to the use of Bupleurum total polysaccharides in the preparation of medicines for preventing and treating acute respiratory distress syndrome. Background technique:

[0002] Acute respiratory distress syndrome (ARDS) refers to acute and progressive hypoxic respiratory failure caused by various pathogenic factors in and outside the lungs other than cardiogenic, and its clinical characteristics are acute respiratory distress and refractory Acute hypoxemia is one of the more common clinical critical and severe diseases with a high fatality rate. Davidson TA (Davidson TA, Caldwell ES, et al. JAMA, 1999, 281: 354.) reported that the mortality rate of ARDS was as high as 30%-40% in the past ten years. Patients with severe atypical pneumonia (SARS) may also experience respiratory ...

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