Synthesis method for dibenzoxazole compounds

A synthesis method and benzoxazole technology are applied in the synthesis field of bisbenzoxazole compounds, can solve the problems of long reaction time, unfavorable environment, large amount of alkali, etc., and achieve short reaction time, less three wastes and low cost Effect

Active Publication Date: 2008-03-19
SHENYANG RES INST OF CHEM IND +1
1 Cites 4 Cited by

AI-Extracted Technical Summary

Problems solved by technology

[0005] In order to overcome the disadvantages of long reaction time, large consumption of acid and alkali, and unfavorable environment when preparing bisbenzoxazole compounds in the prior art, the present invention...
View more

Abstract

The invention discloses a synthesis method of a dibenzoxazole type compound. In organic sovlent, a closed-loop condensation reaction is directly carried out between an aromatic dinitrile compound and substituted or nonsubstituted o-aminophenol hydrochloride to synthesize the dibenzoxazole compound or compounds with different substituents, and the composite proportion of the compound can be regulated according to different raw material proportionings. The method has the advantages of smooth reaction process, short reaction time, high yield rate of products, low cost, little three wastes, environmental protection, etc. and better faciliates large-scale production. The product produced by the method can be applied to the fluorescent whiting of synthesized or natural polymeric materials.

Application Domain

Organic chemistry

Technology Topic

Closed loopOrganic solvent +7

Image

  • Synthesis method for dibenzoxazole compounds
  • Synthesis method for dibenzoxazole compounds
  • Synthesis method for dibenzoxazole compounds

Examples

  • Experimental program(4)

Example Embodiment

[0034] Example 1
[0035] Put 11.5g (0.05mol) of 4,4'-dicyanostyrene, 16g (0.11mol) of o-aminophenol hydrochloride, and 90g of nitrobenzene into a 150ml three-necked flask. Sealed, evacuated, and replaced with nitrogen. The temperature is increased to 190-200°C, and the reaction is completed after rapid stirring and holding for 3 hours. Cool down, filter, and dry. 19.5 g of 4,4'-bis(benzoxazol-2-yl)stilbene was obtained.

Example Embodiment

[0036] Example 2
[0037] In a 150ml three-necked flask, put 9g (0.05mol) of naphthalene-1,4-dinitrile, 16g (0.11mol) of o-aminophenol hydrochloride, and 90g of sulfolane. Sealed, evacuated, and replaced with nitrogen. The temperature is increased to 200-230°C, and the reaction is completed after rapid stirring and holding for 3 hours. 17 g of 1,4-bis(benzoxazol-2-yl)naphthalene was obtained.

Example Embodiment

[0038] Example 3
[0039] In a 150ml three-necked flask, respectively 4,4'-dicyanostilbene 11.5g (0.05mol), o-aminophenol hydrochloride 8g (0.055mol), o-amino-p-methylphenol hydrochloride 8.8g (0.055mol) ), 80g sulfolane. Sealed, evacuated, and replaced with nitrogen. The temperature is increased to 190-200°C, and the reaction is completed after rapid stirring and holding for 3 hours. Cool down, filter, and dry. 19 g of a bisbenzoxazole stilbene mixture was obtained.
[0040] The percentage composition of the mixture determined by liquid chromatography is:
[0041] 4-(benzoxazol-2-yl)-4'-(5-methylbenzoxazole-2-yl) stilbene 49%; 4,4'-bis(benzoxazole-2- Stilbene 24%; 4,4'-bis(5-methylbenzoxazol-2-yl)stilbene 27%.

PUM

no PUM

Description & Claims & Application Information

We can also present the details of the Description, Claims and Application information to help users get a comprehensive understanding of the technical details of the patent, such as background art, summary of invention, brief description of drawings, description of embodiments, and other original content. On the other hand, users can also determine the specific scope of protection of the technology through the list of claims; as well as understand the changes in the life cycle of the technology with the presentation of the patent timeline. Login to view more.

Similar technology patents

Poly(butylene succinate) and preparation method thereof

InactiveCN102604051AEsterification reaction speed is fastshort reaction time
Owner:SHAANXI UNIV OF SCI & TECH

Preparation method of polyamide-imide copolymer

Owner:SHANGHAI PLASTICS RES INST CO LTD

Fermentation process for culturing schizochytrium limacinum with high grease content

PendingCN114164125AThe reaction process is stablelow cost
Owner:HUNAN AGRICULTURAL UNIV +1

Synthetic method of divalent cobalt molybdenum salt-doped polyaniline

InactiveCN107434849AThe reaction process is stableHigh product purity
Owner:佛山杰致信息科技有限公司

Catalyst system and application thereof in reaction for preparing aliphatic polyester

ActiveCN104558545Ashort reaction timeThe reaction process is stable
Owner:CHINA PETROLEUM & CHEM CORP +1

Classification and recommendation of technical efficacy words

  • short reaction time
  • The reaction process is stable

High-concentration fast preparation method for silver nanowires

InactiveCN101934378Ashort reaction timeImprove reaction efficiency and equipment utilization
Owner:ZHEJIANG UNIV

Method for on-line synthesizing glucose-6-palmitate by lipase catalysis

ActiveCN103184249Ashort reaction timeHigh reaction selectivity and conversion
Owner:ZHEJIANG UNIV OF TECH

Method for synthesizing dyestuff intermediate H acid by naphthalene

ActiveCN101717355AThe reaction steps are simpleshort reaction time
Owner:泰兴锦汇化工有限公司

Synthetic method of divalent cobalt molybdenum salt-doped polyaniline

InactiveCN107434849AThe reaction process is stableHigh product purity
Owner:佛山杰致信息科技有限公司

Fermentation process for culturing schizochytrium limacinum with high grease content

PendingCN114164125AThe reaction process is stablelow cost
Owner:HUNAN AGRICULTURAL UNIV +1

Catalyst system and application thereof in reaction for preparing aliphatic polyester

ActiveCN104558545Ashort reaction timeThe reaction process is stable
Owner:CHINA PETROLEUM & CHEM CORP +1
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products