32 results about "O-aminophenol" patented technology

The invention relates to curcumin-loaded pectin sodium alginate gel as well as a preparation method and application thereof, and belongs to the technical field of gel preparation. The preparation method of the curcumin-loaded pectin sodium alginate gel comprises the following steps: in a dark environment, stirring and mixing curcumin, arjunic acid, ortho-aminophenol and an organic solvent, adding a polyvinyl alcohol aqueous solution, a sodium alginate solution and a pectin solution, uniformly mixing, performing ultrasonic treatment, adding calcium chloride, stirring and mixing, performing ultrasonic treatment, and performing vacuum drying to obtain the curcumin-loaded pectin sodium alginate gel. And adding oxidized hyaluronic acid, continuously stirring, stirring at normal temperature until the organic solvent is completely volatilized, and cleaning the hydrogel with deionized water to obtain the hydrogel. According to the invention, calcium ions and sodium alginate are subjected to physical crosslinking, pectin and polyvinyl alcohol are combined to form a composite hydrogel layer, the compounding of multiple components can effectively control the dissolution and drug release behaviors of active components, the bioavailability of curcumin is increased, the compactness and stability of hydrogel are increased, and the bioavailability of curcumin is improved. The oxidation resistance of the hydrogel can be effectively improved.

The invention discloses a preparation method of a post-metallocene catalyst. The method comprises the following steps: by taking quinoline 2-formaldehyde and ortho-aminophenol as raw materials, carrying out reflux reaction on the raw materials and a first solvent to prepare a ligand; dispersing a metal chloride in a second solvent, adding a Grignard reagent, and carrying out a reaction at a low temperature to prepare a methylated metal reagent; and adding a ligand into the methylated metal reagent, reacting at room temperature for 10-12 hours, removing liquid in vacuum, adding part of the second solvent again, stirring, filtering after the product is dissolved, and recrystallizing the filtrate to obtain the product, the metallocene catalyst is obtained by firstly preparing the ligand, then preparing the methylated metal reagent, adding the ligand into the methylated metal reagent for reaction, then stirring by using the second solvent, filtering after the product is dissolved, and recrystallizing the filtrate, so that the operation steps are simple, and the preparation of the ligand does not need water-oxygen treatment operation, and is simple and easy to implement; the preparation cost of the post-metallocene catalyst is reduced, and the method is suitable for industrial large-scale production.

Preparation of polyimides and functional polyimides comprising novel indane bis-o-aminophenols and photosensitive compositions obtained therefrom are described.

The utility model relates to the technical field of o-phenylphenol, in particular to an o-aminophenol production buffer tank convenient to fix, which comprises a buffer tank, a plurality of groups of supporting legs are fixedly mounted at the bottom of the buffer tank, universal wheels are mounted at the bottom of each group of supporting legs, and positioning mechanisms are arranged at the bottoms of the supporting legs. The fixing mechanisms are matched with the positioning mechanisms and need to be poured in the ground, each positioning mechanism comprises a guide column capable of ascending and descending, a chain is fixedly installed at the bottom of each guide column, each fixing mechanism comprises a fixing sleeve which is vertically arranged, and the inner diameter of each fixing sleeve is consistent with that of each guide column; according to the buffer tank convenient to fix and used for ortho-aminophenol production, the buffer tank can be conveniently positioned, displacement and shaking of the buffer tank in the production process are avoided, and the stability of ortho-phenylphenol production is further improved.

This invention relates to a method for identifying and detecting urinary biomarkers of whole-grain wheat intake. These biomarkers include glycine conjugates of 3,5-dihydroxybenzoic acid, sulfate conjugates of o-aminophenol, sulfate conjugates of 2-acetaminophen, sulfate conjugates of 3,5-dihydroxyphenylvaleric acid, glucuronic acid conjugates of o-aminophenol, or glucuronic acid conjugates of 2-acetaminophen. The invention also relates to a high-throughput screening method for urinary biomarkers of whole-grain wheat intake. A whole-grain wheat dietary intervention experiment was designed, and through comparative analysis of human urinary metabolic profiles, non-targeted metabolomics technology was used to screen for urinary metabolic biomarkers of whole-grain wheat, providing a method for accurately assessing whole-grain wheat intake.

The invention relates to an environment-friendly stripping agent of photosensitive ink for electroplating shielding, and belongs to the technical field of stripping agents. The preparation method comprises the following steps: carrying out nucleophilic addition on phosphorous acid and diethylene glycol monobutyl ether to obtain a modified precursor containing a phosphoester structure, carrying out Michael addition on the modified precursor and ortho-aminophenol to obtain a modified monomer, carrying out diazotization reaction on the modified monomer and ortho-nitroaniline, and then reducing to obtain the 2-(2-nitrophenyl)-1, 2, 4-thiadiazole. And finally, compounding the modified corrosion inhibitor with a stripping agent system, so as to obtain the environment-friendly stripping agent for the photosensitive ink for electroplating shielding. The environment-friendly stripping agent of the photosensitive ink for electroplating shielding has the advantages of environment friendliness, no toxicity, high stripping efficiency, broad-spectrum corrosion inhibition and few surface residues.

The invention belongs to the technical field of organic synthesis, and particularly discloses a synthesis method of a 2-mercaptobenzothiazole derivative. The preparation method comprises the following steps: by taking salicylic acid which is cheap and easy to obtain as a raw material, carrying out Curtius rearrangement and intermediate hydrolysis to obtain ortho-aminophenol, and then selectively converting the obtained ortho-aminophenol into ortho-aminophenyl phenol trifluoromethanesulfonate; and finally, carrying out ring closing on the 2-mercaptobenzothiazole and potassium ethyl xanthate under a heating reflux condition to obtain the 2-mercaptobenzothiazole. The method has the advantages of mild reaction conditions, wide raw material sources, no need of high-toxicity sulfur-containing intermediates such as carbon disulfide or thiophosgene, and no need of an oxidant in the post-treatment process.

This disclosure describes poly-o-hydroxyamides containing novel indane bis-o-aminophenols, negative tone photosensitive compositions containing same, and methods and articles for use thereof.

The invention relates to an identification and detection method of a whole grain wheat urine intake marker, and the whole grain wheat urine intake marker comprises a glycine conjugate of 3, 5-dihydroxybenzoic acid, a sulfuric acid conjugate of ortho-aminophenol, a sulfuric acid conjugate of 2-acetaminophen, a glycine conjugate of 3, 5-dihydroxybenzoic acid, a sulfuric acid conjugate of 2-acetaminophen, a glycine conjugate of 3, 5-dihydroxybenzoic acid and a sulfuric acid conjugate of 2-acetaminophen. The invention also relates to a sulfuric acid conjugate of 2, 5-dihydroxyphenyl valeric acid, a glucuronic acid conjugate of ortho-aminophenol or a glucuronic acid conjugate of 2-acetaminophen. The invention further relates to a high-throughput screening method of the whole-grain wheat urine intake marker, a whole-grain wheat diet intervention experiment is designed, and the urine metabolism marker of the whole-grain wheat is screened out by utilizing a non-targeted metabonomics technology through contrastive analysis of a human urine metabolism spectrum. And the method is provided for accurately evaluating the intake of the whole-grain wheat.

The present invention relates to a mutant for catalytic synthesis of phenazine and phenoxazine ketone compounds and its application, belonging to the field of bioenzyme engineering technology, wherein the mutant is a cytochrome P450BM3 oxidase in which one or more of the following amino acid sites are mutated: the 87th phenylalanine is mutated to alanine or glycine, the 78th valine is mutated to alanine, and the 264th threonine is changed to alanine, and the specific mutants are F87A, F87G, F87A / V78A / A264G or F87G / V78A / A264G. The present invention also provides an expression vector of any one of the mutants and a genetic engineering bacterium containing the expression vector, and the mutant catalyzes the self-oxidative coupling of aromatic amine substrates including 2,5-diaminobenzenesulfonic acid, o-phenylenediamine or o-aminophenol to generate phenazine and phenoxazine ketone compounds through H2O2, and the yield of the mutant catalyzing o-aminophenol to generate phenoxazine ketone is as high as 99%.

The invention discloses an electrochemical sensor for detecting ortho-aminophenol as well as a preparation method and application of the electrochemical sensor, and relates to the technical field of electrochemical sensors. The CuWO4 (at) MoS2 composite material is obtained by compounding synergism of a high-specific-surface-area supporting structure, electron synergism of heterojunction accelerated charge separation and catalytic synergism of double active sites, and the CuWO4 (at) MoS2 composite material is used for modifying a glassy carbon electrode, so that the electrochemical sensor is constructed. The sensor shows good sensitivity, reproducibility and reliable stability to ortho-aminophenol, and can be used for detecting the content of ortho-aminophenol in a water body sample.

The invention discloses a waterproof and fireproof insulating sealant and a preparation method thereof, and belongs to the technical field of sealants. The waterproof and fireproof insulating sealant comprises the following components in parts by weight: 50-80 parts of modified vinyl silicone rubber, 10-30 parts of an inorganic flame retardant, 5-15 parts of an insulating flame-retardant composite material, 2-8 parts of polydisiloxane, 1-5 parts of dimethyl thiourea, 1-5 parts of methyl silicone oil, 1-5 parts of a preservative, 1-5 parts of an additive and 1-2 parts of pigment, the modified vinyl silicone rubber is obtained by modifying vinyl silicone rubber; the insulating flame-retardant composite material is prepared from bisphenol A type epoxy resin, o-hydroxybenzaldehyde and o-aminophenol. The sealant prepared by the method has excellent waterproof, flame-retardant and insulating properties.

The application provides a preparation method of high-quality 2,2-bis(3-amino-4-hydroxyphenyl)propane, which comprises the following steps: uniformly stirring o-aminophenol, 2,2-dichloropropane and a catalyst, increasing the temperature, and performing heat preservation reaction; after the reaction is completed, the temperature is reduced, white solids are precipitated, filtration is performed, a filtrate and solids are obtained, and the solids are washed, filtered and vacuum-dried to obtain 2,2-bis(3-amino-4-hydroxyphenyl)propane. The preparation method adopts a new process system, raw materials and a catalyst are low in price, environment-friendly, safe in operation, and high in product quality, and is suitable for large-scale production.

There are provided indane bis-o-aminophenol compounds capable of producing soluble polyimides, functional polyimides, and poly-o-hydroxyamides.

The invention provides a method for producing ortho-aminophenol by taking n-butyl alcohol as a solvent, which comprises the following steps: adding hydrogen into ortho-nitrophenol in an n-butyl alcohol-water solvent under the action of a catalyst, and carrying out reduction reaction to obtain ortho-aminophenol feed liquid; crystallizing the ortho-aminophenol feed liquid to obtain an ortho-aminophenol wet material and a mixed mother solution; separating the mother liquor to obtain recovered mother liquor containing n-butyl alcohol and a water phase; and using the recovered mother liquor containing n-butyl alcohol as a solvent for the reduction reaction. Compared with the conventional process taking methanol and ethanol as solvents, the method has the advantages that the process and time for recovering the mother liquor are shortened, and the production efficiency is improved; the recovery rate of ortho-aminophenol in the mother liquor is increased, meanwhile, solid waste difficult to treat generated in the mother liquor rectification process is reduced, and environmental pollution is reduced; the water-phase rectification is intermittent operation, and the mother liquor can be used mechanically, so that the amount of a rectification solvent is reduced compared with the solvent rectification of a conventional process.

The invention belongs to the technical field of catalysts, and particularly relates to a coordination polymer based on phosphorus-molybdenum-vanadium polyacid and a preparation method thereof.The coordination polymer is used for a heterogeneous catalyst for oxidation self-coupling reaction of ortho-aminophenol compounds and comprises a polyacid anion cluster, the chemical formula of the polyacid anion cluster is HPMoxVyOzk-, transition metal M and a first ligand i-Pr-Im, the first ligand Phen is an N-alkyl substituted imidazole ligand, and the second ligand Phen is 1, 10-phenanthroline or a derivative thereof. The wave-passing metal M is connected with the i-Pr-Im, Phen and oxygen atoms of the polyacid anion cluster through coordinate bonds to form a one-dimensional chain coordination polymer structure; the general formula of the coordination polymer is [M (i-Pr-Im) a] [M (i-Pr-Im) (Phen) b] c [HPMoxVyOz] * nH2O. The coordination polymer is based on a heterogeneous catalyst of non-noble metal, cheap oxygen or air is used as an oxidizing agent, and oxidation from OAPs to APXs is realized under the condition of no additive.

This disclosure describes highly soluble novel poly-o-hydroxyamides containing new indane bis-o-aminophenols, photosensitive compositions containing same, and methods and articles for use thereof.

Preparation of polyimides and functional polyimides comprising novel indane bis-o-aminophenols and photosensitive compositions obtained therefrom are described.

This disclosure describes highly soluble novel poly-o-hydroxyamides containing indane bis-o-aminophenols, photosensitive compositions containing same, and methods and articles for use thereof.

There are provided indane bis-o-aminophenol compounds capable of producing soluble polyimides, functional polyimides, and poly-o-hydroxyamides.

The present invention relates to the field of nano-enzyme-mimicking catalytic materials, and specifically provides a spindle-shaped Cu-Ru bimetallic mesoporous nano-mimetic enzyme and a preparation method and application thereof. The material has good nano-mimetic oxidase activity and simulated peroxidase activity, and can play a bifunctional nano-enzyme role. The material is guided by a positive hexadecyltrimethylammonium bromide (CTAB) template, and a copper-ruthenium bimetallic-based nano-mimetic enzyme (CTAB@Cu-Ru) is prepared by a "one-pot reduction method". The copper-ruthenium metals interact strongly with each other, further promoting charge transfer between each other, and synergistically enhancing the catalytic activity of the CTAB@Cu-Ru simulated oxidase / peroxidase. In detection applications, the CTAB@Cu-Ru nano-mimetic enzyme has excellent specificity and selectivity for o-aminophenol and m-aminophenol, good anti-interference, and is convenient and fast, highly sensitive, accurate in detection results, and highly visible, and can effectively detect ultra-trace o-AP and m-AP in environmental samples.

This disclosure describes highly soluble novel poly-o-hydroxyamides containing indane bis-o-aminophenols, photosensitive compositions containing same, and methods and articles for use thereof.

The invention relates to the technical field of chemical synthesis, and discloses a preparation process of 8-hydroxyquinoline, which comprises the following steps: 1, adding o-nitrophenol and o-aminophenol into a reaction container; step 2, adding concentrated sulfuric acid and glycerol, and heating; step 3, after cooling, adding an organic phase enrichment solvent and an alkaline solution; and 4, blending and converting 8-hydroxyquinoline in the organic phase and the water phase, adjusting the pH value, and separating out the product. The problem of viscous tar is avoided, so that filtering and separation become convenient.

This invention provides a method for preparing benzoxazine film-forming resin precursor materials and their applications, belonging to the fields of organic synthesis and semiconductor photoresist technology. The method uses substituted o-aminophenol as a starting material and proceeds through four steps: nucleophilic substitution cyclization, regioselective bromination, amide-selective reduction, and reductive amination, to prepare N-substituted brominated dihydrobenzoxazine compounds. This invention achieves specificity of the sequential reaction sites through differences in reactivity and control of process parameters, resulting in products with high purity and ultra-low or even no metal ion residue. The N-substituted brominated dihydrobenzoxazine compounds prepared by this invention have low curing temperatures, high crosslinking activity, and possess both bromine atom active sites and a rigid benzoxazine framework, making them suitable as precursor materials for film-forming resins in photoresists.

This disclosure describes poly-o-hydroxyamides containing novel indane bis-o-aminophenols, negative tone photosensitive compositions containing same, and methods and articles for use thereof.

The invention discloses a preparation method of 5-nitro-2-aminophenol, which comprises the following specific steps: dispersing raw materials of halogenated nitroaniline and a catalyst in a sodium hydroxide aqueous solution, reacting for 12-22 hours under the conditions that the reaction temperature is 80-120 DEG C and the pressure is 0.3-1.5 MPa, hydrolyzing the halogenated nitroaniline to obtain a crude product of 5-nitro-2-aminophenol, and purifying the crude product of 5-nitro-2-aminophenol to obtain the 5-nitro-2-aminophenol. And after the reaction is finished, cooling to room temperature, carrying out suction filtration, washing with water, and drying to obtain the pure product 5-nitro-2-aminophenol. Compared with an industrial ortho-aminophenol method, the method has the advantages that halogenated nitroaniline is used as a raw material, three-step reaction is shortened into one-step reaction, reaction operation is simple, raw materials are cheap and easy to obtain, the yield is high, the production cost is reduced by 20%, and economic benefits of enterprises are greatly improved.

The application relates to the technical field of organic silicon materials, in particular to a high-temperature-resistant coupling agent and application of the high-temperature-resistant coupling agent in a polyphenyl ether base material circuit board, wherein the high-temperature-resistant coupling agent has a structure shown in formula I. The high-temperature-resistant coupling agent is prepared by coupling reaction of an o-aminophenol compound and p-phenyloxy iodobenzene to obtain an intermediate, and then reacting the intermediate with chlorosilane in the presence of alkali. The high-temperature-resistant coupling agent contains an aromatic ring structure, a siloxane group and a polar adaptive site at the same time, has high matching degree with polyphenyl ether resin, benzoxazine resin, inorganic fillers and metal foils, can significantly improve the interface bonding force between copper foils and polyphenyl ether base materials, is synthesized by a two-step method, has mild reaction conditions, simple post-treatment, stable yield and less waste, and is suitable for large-scale industrial production.

The invention discloses a method for preparing ortho-aminophenol through continuous catalytic hydrogenation, which comprises the following steps: premixing a raw material solution containing ortho-nitrophenol with hydrogen, feeding into a tubular reactor filled with a specific composite catalyst, carrying out catalytic hydrogenation reaction, separating the reaction effluent through an online membrane separation unit to obtain a product penetrating fluid, and carrying out continuous catalytic hydrogenation on the product penetrating fluid to obtain the ortho-aminophenol. Meanwhile, trapped fluid containing unreacted materials and the catalyst is returned to the system for circulation; wherein the process parameters are dynamically adjusted by the intelligent control system according to parameters such as product concentration and flow monitored on line. Through system integration of catalyst design, reaction-separation coupling and intelligent control, high-efficiency and high-selectivity production under lower pressure is realized, the yield and purity of ortho-aminophenol are greatly improved, and the system is stable and controllable in operation and has the outstanding advantages of safety, energy conservation and high product quality.

This disclosure describes highly soluble novel poly-o-hydroxyamides containing new indane bis-o-aminophenols, photosensitive compositions containing same, and methods and articles for use thereof.