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Medicinal composition

A composition and drug technology, which can be used in drug combinations, pharmaceutical formulations, blood diseases, etc., can solve the problems of certain difficulties in the research and development and production of compound drugs.

Inactive Publication Date: 2008-08-13
BEIJING TRADE STAR MEDICAL TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Due to the frequent reports of adverse reactions of compound drugs of chemical drugs and traditional Chinese medicines, the China Food and Drug Administration issued the "Regarding the Suspension of Acceptance of Registration Applications for 117 Varieties of Drugs with National Standards, including Ginkgo Damo Injection, on February 2, 2005." From this point of view, it is still difficult to develop and produce compound drugs with definite curative effect and stable quality.

Method used

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  • Medicinal composition
  • Medicinal composition
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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023]

[0024] 1000g of 5'-hydroxyrutin was catalyzed by 30gKOH, acylated with excess benzoyl chloride under the condition of 50 degrees Celsius, and then hydrolyzed to obtain compound A1127g.

Embodiment 2

[0026]

[0027] 1000g of 5'-hydroxyrutin was catalyzed by 30gKOH, acylated with excess benzoyl chloride under the condition of 50 degrees Celsius, and then hydrolyzed to obtain compound B1223g.

Embodiment 3

[0029] 300g of compound A was added with 50ml of quinoline and 0.3g of silver oxide at 30°C, reacted for 5 hours, and then hydrolyzed with 0.01mol / L dilute hydrochloric acid to obtain 122g of compound C.

[0030]

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PUM

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Abstract

The invention belongs to the technical field of traditional Chinese medicine and in particular discloses a medicine compound which contains flavone and dextrosamine of a certain percentage. Through the coordinate action of flavone and dextrosamine, the product of the invention can be used for the treatment of cardiovascular diseases.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine, and in particular relates to a pharmaceutical composition containing flavonoids and glucosamine, a preparation method, and an application in disease treatment. Background technique [0002] Flavonoids refer to a general term for a large class of compounds based on a 6-3-6 carbon skeleton. This type of compound containing oxygen heterocycles mostly exists in higher plants and ferns. As of 2000, statistics, The total number of flavonoids has exceeded 8,000; the structure types are as many as the number and position of the hydroxyl, methyl and other substituents of each category are different. Flavonoids usually exist in the form of glycosides, and there are also free bodies (aglycones); in addition to O-glycosides, C-glycosides are also found in natural flavonoids, such as puerarin and puerarin xyloside. [0003] Flavonoids are widely distributed in the plant kingdom and have ...

Claims

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Application Information

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IPC IPC(8): A61K31/7048A61K31/7008A61P7/02A61P9/00
Inventor 司成桃张秀华
Owner BEIJING TRADE STAR MEDICAL TECH