Medicinal composition for treating stomach and intestine dysfunction and preparation thereof

A technology of gastrointestinal dysfunction and composition, applied in the field of new drugs, can solve problems such as unclear pathogenesis, drug development needs to be further improved, and easy recurrence

Inactive Publication Date: 2008-09-17
BEIJING ZHONGKE RENHE SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there are many drugs clinically used to treat gastrointestinal diseases, but because the pathogenesis of gastrointestinal dysfunction is not clear, therefore, clinical treatment is mainly based on superficial symptoms, such as the application of drugs such as analgesic and antidiarrheal, although they can be used temporarily. Relieve clinical symptoms, but it is very easy to relapse, and the prognosis is not satisfactory
[0004] my country's traditional Chinese medicine has a good therapeutic prospect in the treatment of gastrointestinal dysfunction, but the further exploration of the TCM theory of gastrointestinal dysfunction and the development of such drugs still need to be further improved

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] Prescription composition:

[0027] Atractylodes macrocephala 180g Golden buckwheat 240g Astragalus 180g

[0028] Rehmannia glutinosa 180g Angelica 120g Yam 120g

[0029] Codonopsis 120g Poria cocos 120g Chenpi 120g

[0030] Zhi Licorice 60g

[0031] A total of 1000 capsules were made

[0032] Preparation:

[0033] (1) Get golden buckwheat, grind into coarse powder, use 10 times the amount of 50% ethanol to reflux extract for 3 hours, extract the alcohol solution to filter, add 10 times the amount of 50% ethanol to reflux extract for 2 hours, extract the alcohol solution to filter, Add 10 times the amount of 50% ethanol to the dregs and extract under reflux for 2 hours, filter the extracted alcohol solution, combine the filtrates, recover the ethanol under reduced pressure and concentrate it to a clear paste with a relative density of 1.30 (55°C) for later use;

[0034] (2) Take Atractylodes macrocephala, astragalus, rehmannia glutinosa, angelica, yam, Codonopsis pi...

Embodiment 2

[0038] Prescription composition:

[0039] Atractylodes macrocephala 60g Golden buckwheat 80g Astragalus 60g

[0040] Rehmannia glutinosa 60g Angelica 40g Yam 40g

[0041] Codonopsis 40g Poria cocos 40g Chenpi 40g

[0042] Roasted licorice 20g sucrose 930g

[0043] Made a total of 1000g

[0044] Preparation:

[0045] (1) Get golden buckwheat, grind into coarse powder, use 10 times the amount of 50% ethanol to reflux extract for 3 hours, extract the alcohol solution to filter, add 10 times the amount of 50% ethanol to reflux extract for 2 hours, extract the alcohol solution to filter, Add 10 times the amount of 50% ethanol to the dregs and extract under reflux for 2 hours, filter the extracted alcohol solution, combine the filtrates, recover the ethanol under reduced pressure and concentrate it to a clear paste with a relative density of 1.30 (55°C) for later use;

[0046] (2) Take Atractylodes macrocephala, astragalus, rehmannia glutinosa, angelica, yam, Codonopsis pilosul...

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PUM

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Abstract

The invention discloses a medicine composition for curing gastrointestinal dysfunction and the preparation method. The invention comprises the active pharmaceutical ingredients with the following weight proportion: Largehead Atractylodes Rhizome 10 to 60 weight shares, (rhizoma fagopyricymosi wild buckwheat rhizome 10 to 50 weight shares, astragalus 10 to 50 weight shares, prepared rhizome of rehmanniae 10 to 50 weight shares, angelica sinensis 10 to 40 weight shares, Chinese yam 10 to 40 weight shares, lanceolata 10 to 40 weight shares, poria cocos 10 to 30 weight shares, tangerine peel 10 to 30 weight shares and baked radix glycyrrhizae 5 to 20 weight shares. The medicine composition has the functions of spleen strengthening, stomach regulating, spleen invigorating and qi replenishing, and is used for curing anorexia, wiredness, tiredness and anorexia caused by gastrointestinal dysfunction.

Description

technical field [0001] The invention relates to a pharmaceutical composition and a preparation method thereof, in particular to a pharmaceutical composition for treating gastrointestinal dysfunction and a preparation method thereof, belonging to the technical field of new drugs. Background technique [0002] Gastrointestinal dysfunction, also known as functional gastrointestinal motility disease, is a group of gastrointestinal syndromes. Clinically, it often manifests as gastrointestinal pain, poor appetite, acid regurgitation, abdominal distension, constipation, diarrhea and other symptoms, but there is no evidence of clinical examination. The pathogenesis of organic disease is still unclear, and it is difficult to cure clinically. [0003] Gastrointestinal dysfunction is a syndrome of spleen-qi deficiency in traditional Chinese medicine, which refers to the syndrome caused by deficiency of spleen and stomach qi and dysfunction of transportation and chemistry. It is mostly ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8945A61P1/00A61P1/14
Inventor 颜丽君
Owner BEIJING ZHONGKE RENHE SCI & TECH
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