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Composition containing plant effective component and preparation method and use thereof

The technology of a composition and preparation is applied in the field of the composition of effective components of ginseng and the field of preparation thereof, and can solve the problems of not fully exerting the function and curative effect of ginseng and the like

Inactive Publication Date: 2008-12-24
TASLY HLDG GRP CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0014] At present, the medicines containing the active ingredients of ginseng are all used as one of the active ingredients of ginseng, such as ginsenosides or ginseng polysaccharides, which have not fully exerted the functions and curative effects of ginseng

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0090] Take 500g ginseng, add distilled water to decoct 3 times, the amount of water added is 3000ml, 2500ml, 2500ml respectively, and the decocting time is 2 hours, 2 hours, 1.5 hours respectively. The combined extracts were concentrated to 800ml, and 95% ethanol was added to make the alcohol concentration 80%. Filter the precipitate, redissolve it in water, add 95% ethanol to make the alcohol concentration 70%, filter the precipitate, and dry in vacuo to obtain 20.4 g of ginseng polysaccharides, and measure the polysaccharide content in the ginseng polysaccharides by the anthrone-sulfuric acid colorimetric method was 75.8%.

[0091] Take 500g of ginseng, add 75% ethanol to reflux and extract three times, the dosage of 75% ethanol is 3000ml, 2500ml, 2500ml respectively, and the reflux time is 2 hours, 2 hours, 1.5 hours respectively. Combine the extracts, and concentrate under reduced pressure until there is no alcohol smell, and put the concentrated solution on D 101 The m...

Embodiment 2

[0094] Take 500g of ginseng, pass through a 80-100 mesh sieve, soak in water overnight, dry, soak and extract with 75-80% ethanol or reflux for at least 5 times, volatilize the dregs of the ginseng, soak in water, heat to boiling, and keep slightly Boiling extraction, a total of 5 extractions, combined extracts, concentrated to 1 / 10 volume, added 95% ethanol or absolute ethanol to 40% alcohol, centrifuged at 3000rpm for 15 minutes, discarded the precipitate, and continued to add 95% ethanol to the supernatant. % ethanol or absolute ethanol, until the alcohol concentration is 60%, add 95% ethanol or absolute ethanol after concentration, until the alcohol concentration is 80%, centrifuge at 3000rpm for 15 minutes, collect the precipitate, and soak it with absolute ethanol for 1-2 times , to obtain ginseng polysaccharide 18.7g.

[0095] Take 1000g of ginseng, reflux extraction with 75% ethanol for 4 times, each time with 8 times the amount of ethanol for reflux extraction for 1.5...

Embodiment 3

[0098] Take 250g ginseng, decoct it with water for 3 times, 2 hours each time, combine the extracts, precipitate with 75% of the extracts, dry the precipitates to remove ethanol to the utmost, dissolve the dry precipitates in water, after the dissolution is complete, refrigerate overnight, take the supernatant and concentrate to The relative density is about 1.2 (measured at 60°C), add 200g of polyamide, mix well, dry, install in a chromatography column, elute with water to collect the eluate, concentrate to a relative density of 1.2 (measured at 60°C), add ethanol to make the ethanol concentration reach 80%, stir, stand still for 12 hours, filter to take the precipitate, wash the precipitate with absolute ethanol 2 to 3 times, and dry in vacuum to obtain 15.6 g of ginseng polysaccharide, which is set aside.

[0099] Take 250g of ginseng, reflux and extract with 70% ethanol three times, each time for 2 hours, combine the extracts, and concentrate under reduced pressure until th...

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Abstract

The invention discloses a plant active component composite containing ginseng polysaccharide, total saponins of panax ginseng, and hydrolysate of ginsenoside. The invention also discloses a preparation method thereof and an application thereof for regulating the immunity of the organism and resisting tumor.

Description

technical field [0001] The invention relates to a composition of effective components of plants, in particular to a composition of effective components of ginseng and its preparation method and application. technical background [0002] With the prosperity of society and economy, the accelerated pace of life, and the increasingly fierce competition, modern people, especially middle-aged people, have to shoulder the double burden of family and work. The factors that affect human health have undergone great changes. Long-term overloaded physical strength , Mental work leads to the decline of the body's immune function, so that it causes a variety of diseases. [0003] The development of modern medicine, cell biology and molecular biology has made people realize that the disorder of the immune system will not only cause a variety of diseases, but also have a close relationship with human aging and the occurrence of frequently-occurring diseases of the elderly such as tumors, hi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/258A61K31/715A61P35/00A61P37/04A61K125/00
Inventor 张兰兰凌芳朱永宏高钧李长文叶正良
Owner TASLY HLDG GRP CO LTD
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