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Gene chip

A gene chip and membrane technology, which is applied in the direction of material inspection products, microbial determination/inspection, biochemical equipment and methods, etc., can solve problems such as the promotion, research and utilization of gene chips affecting multiple indicators and multiple parallel detection.

Inactive Publication Date: 2008-12-31
上海裕隆生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

These factors have greatly affected the popularization, research and utilization of multi-indicator and multi-person parallel detection gene chips.

Method used

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Embodiment Construction

[0013] figure 1 The embodiment of the gene chip shown is as follows: take the amino or aldehyde group modified glass slide, and stick a plastic or film sheet on the non-marking area. The diaphragm is 25mm wide, 70mm long and 1mm thick. The hollows arranged in parallel on the top are reaction areas, which can be reaction chambers after being pasted on glass slides. The reaction zone is a square with a length and a width of 8 mm. The place on the glass slide corresponding to the reaction zone can be spotted and combined with nucleic acid probes related to the disease to be detected.

[0014] figure 2 The embodiment of the gene chip shown is as follows: take a silicon chip modified with amino groups or aldehyde groups, and stick a plastic or film sheet on the non-marking area. The diaphragm is 80mm wide, 80mm long and 3mm thick. The hollows arranged in parallel on the top are reaction areas, which can be reaction chambers after being pasted on the silicon wafer. The reacti...

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Abstract

The invention provides a convenient and economic combined gene chip which relates to the technical fields of the bio-chip technology and the in vitro clinical diagnosis and detection, and the combined gene chip is formed by combining a carrier and a sticky membrane which has a pierced reaction zone and covers on the carrier. The combined gene chip is used for conveniently and rapidly carrying out the multi-disease and multi-person parallel diagnosis, the requirements on the manufacturing process of the carrier of the gene chip are simultaneously reduced, the cost input is reduced, and the combined gene chip is conductive to the popularization and the application of the gene chip for the multi-indicator and multi-person parallel detection.

Description

technical field [0001] The invention relates to the technical fields of biochip technology and in vitro clinical diagnosis and detection, and more specifically relates to a gene chip suitable for multi-indicator and multi-person parallel detection. Background technique [0002] Gene chips were originally produced due to the need for high-throughput and large-scale research on gene functions, such as the most popular chip product of the American Affymetrix company on the market. With the increasing maturity of chip technology, it has been found that gene chips have unique application prospects and huge commercial markets in the diagnosis of infectious diseases and genetic diseases. Related research designs are also being developed. From the perspective of economic cost and high-efficiency detection, there are also multi-indicator and multi-person gene chip designs. For example, the multi-person diagnostic gene chip carrier mentioned in the application number 00114996 of Sha...

Claims

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Application Information

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IPC IPC(8): G01N33/50C12Q1/00
Inventor 穆海东汪宁梅黎飒罗芳英
Owner 上海裕隆生物科技有限公司
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