Production method of 1,2- benzisothiazole-3-ketone
A technology of benzisothiazole and its production method, which is applied in the fields of air quality improvement and organic chemistry, can solve problems such as air pollution, increase in production cost, pollution, etc., and achieve the effects of avoiding pollution and reducing production cost
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Examples
Embodiment 1
[0011] Add 100g of o-chlorobenzonitrile and 2g of catalyst tetrabutylammonium bromide into a four-neck flask, heat up to 50°C under stirring, then slowly add 200ml of 20% sodium methyl mercaptide solution dropwise to carry out vulcanization reaction, and drop it over in 4 hours , continue to react for 2h, cool and stand still, remove the lower aqueous phase, and wash the upper organic phase twice with 200ml of water;
[0012] Put the organic phase (102ml) obtained by the sulfidation reaction into an Erlenmeyer flask, add 30.6ml of water, feed 77.5g of chlorine gas under stirring, react for 2h, control the reaction temperature to 15°C with cooling water, and wait until the organic phase completely disappears After forming a powdery white suspended solid, filter and wash the filter cake twice with 200ml of water, and dry at 50°C for 5 hours to obtain 93.23g of BIT product with a purity of 98.6%, and a yield of 92%.
Embodiment 2
[0014] Add 50g of water, 100g of o-chlorobenzonitrile and 2g of catalyst tetrabutylammonium bromide into a four-necked flask, and under stirring, raise the temperature to 80°C and add 300ml of 20% sodium methyl mercaptide solution dropwise for vulcanization reaction, and drop it for 6 hours , continue to react for 6h, cool and stand still, remove the lower aqueous phase, and wash the upper organic phase twice with 200ml of water;
[0015] Put the organic phase (101ml) obtained by the sulfidation reaction into an Erlenmeyer flask, add 202ml of water, 103g of chlorine gas under stirring, react for 5h, control the reaction temperature to 30°C with cooling water, until the organic phase completely disappears to form a powdery white suspension After solid, filter and wash the filter cake twice with 200ml of water, dry at 80°C for 5h to obtain 94.75g of BIT product with a purity of 99.2%, and a yield of 93.5%.
PUM
Abstract
Description
Claims
Application Information
- R&D Engineer
- R&D Manager
- IP Professional
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com