Dedicated spectral illumination spectroscopy

A spectrum and reflected light technology, applied in color/spectral characteristic measurement, material analysis and application through optical means, can solve problems such as limitation and limitation of total power

Inactive Publication Date: 2009-06-17
KONINK PHILIPS ELECTRONICS NV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, on the one hand, the total power is limited due to safety reasons; on the other hand, the total power is limited by saving battery power in portable devices.

Method used

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Examples

Experimental program
Comparison scheme
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Embodiment Construction

[0061] figure 1 Describes the method used to determine analyte levels.

[0062] Although the method is described for glucose determination, it can be used for various analytes with optical properties, such as cholesterol (HDL and LDL), urea, uric acid, triglycerides, albumin, bilirubin, and others substance.

[0063] In the first step S1, a wavelength that is highly related to glucose absorption is selected, or a wavelength that is generally highly related to the analyte of interest is selected.

[0064] This step involves irradiating the reference sample with broadband light in order to take into account all substances that may interfere with the glucose measurement. Broadband light can be provided by an incandescent lamp that does not exhibit a strong spectral change in the wavelength range used.

[0065] Select the reference sample to simulate all the changes that may occur during the measurement. Specifically, these samples are glucose with a known concentration (in a prefer...

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Abstract

Apparatus and method for an analyte determination in blood, relying on spectroscopic techniques, in which sample is illuminated with light having dedicated spectral characteristics. The first light source (20) is a broadband light source in the IR-range, the second light source (25) is comprised of one or more monochromatic sources, such as laser diodes. The sources are chosen to correspond to wavelength highly correlated with glucose adsorption.

Description

Technical field [0001] The present invention relates to an apparatus and method for determining the level of an analyte in the blood, and more particularly to an apparatus and method for determining the level of glucose in the blood in a non-invasive manner. Background technique [0002] The measurement of analyte concentration in the blood has some applications in various diagnosis and treatment of various physical conditions. An important application is to determine the blood glucose level of diabetic patients. [0003] Diabetes is a disease associated with defects in the biological mechanism that regulates blood sugar (ie, the concentration of glucose in the blood). In order to help regulate blood sugar during the day and reduce a large number of physiological problems that may occur in diabetic patients, these physiological problems include complex degenerative effects. In terms of eyes, these degenerative effects are specifically retinopathy, uveolar metabolism, or cataracts...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N21/31A61B5/00
CPCA61B5/14532G01N21/359A61B5/1455G01N21/314
Inventor W·伦森G·冯巴撒姆M·劳布舍尔G·吕卡森M·帕拉西奥斯
Owner KONINK PHILIPS ELECTRONICS NV
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