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Fungicidal compositions and methods of using the same

A composition, fungicidal technology, applied in the directions of application, small hides/large hides/leather/fur treatment, leather impregnation, etc.

Inactive Publication Date: 2009-07-01
BUCKMAN LAB INT INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0016] However, these "minimum risk pesticides" are generally not considered very effective pesticides by the industry

Method used

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  • Fungicidal compositions and methods of using the same
  • Fungicidal compositions and methods of using the same
  • Fungicidal compositions and methods of using the same

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0074] Each material shown in table 1 is added in the inorganic salt glucose culture medium with following composition, to screen the antifungal activity of these materials: 0.7g KH 2 PO 4 ;0.7g MgSO 4 .7H 2 O; 1 g NH 4 NO 3 ; 0.005g NaCl; 0.002g FeSO 4 .7H 2 O; 0.002g ZnSO 4 .7H 2 O; 0.001g MnSO 4 .7H 2O; 10 g glucose; 100 ml water. The pH of the medium was adjusted to 6 using 1N NaOH. 50ml of medium was dispensed into 250ml flasks and autoclaved at 121°C for 20 minutes. The fungus tested, Aspergillus niger, was grown on potato dextrose agar for 7-10 days. A spore / hyphae suspension of the fungus was prepared by washing the spores / hyphae from a slant with sterile saline into a bottle containing 30 ml sterile saline and shaking. Each chemical was added to sterile mineral salt medium at the desired concentration and each flask was inoculated with a fungal suspension such that the final fungal count was about 1 x 10 6 cfu / ml. The inoculated samples were incubated a...

Embodiment 2

[0086] Those substances which demonstrated significant antifungal activity in Example 1 above were further tested in vitro on wet tanned rawhide hides (wet chrome tanned leather). A 1 inch square piece of wet chrome-tanned leather that had not been previously treated with fungicides was dipped in either 0.5% or 0.25% (wt %) mixtures of the various actives in water. Sodium 2-mercaptopyridine was included as a positive control among the test substances. The test organism A. niger was grown on potato dextrose agar for 5 days in petri dishes. The wet chrome-tanned leather pieces were placed on top of each section of a curved glass rod, preventing direct contact with the "lawn" of A. niger. Therefore, limiting the exposure of wet chrome-tanned leather to airborne A. niger spores is one of the most common ways of simulating the exposure experienced in practice. For each active substance and concentration studied, pieces of wet chrome-tanned leather were suspended with the grain si...

Embodiment 3

[0097] As shown in Table 3, some of the minimal risk fungicides identified above were further tested for resistance to industrial isolates of penicillium samples (Penicillium sp). This particular "wild strain" of penicillin was isolated from commercial wet chrome tanned leather heavily contaminated with the mold. In this case, the included molds significantly stain the wet chrome tanned leather, resulting in a significant loss of commercial value. Once again, a 1 inch square piece of wet chrome tanned leather was dipped in a mixture of active material in water, this time at concentrations of 1% and 0.5%. Mold exposures were performed in Petri dishes as in Example 2, but using penicillin samples as test organisms. Again, the resistance of wet chrome tanned leather treated with sodium lauryl sulfate or thyme oil was significantly improved over the unprotected control. The commercial fungicide Prosan from Buckman Laboratories International included as a positive control TM 18...

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Abstract

Methods of preventing or inhibiting putrefaction, degradation, and / or deterioration of a surface of wet animal hide or skin are described. The method can include applying a composition containing at least one minimum risk fungicide to the surface or to a solid, liquid or gas that comes in contact with the surface. Treated hides or skin are further described.

Description

field of invention [0001] Under 35 U.S.C. §119(e), this application claims the benefit of prior U.S. Provisional Patent Application 60 / 795,864, filed April 28, 2006, which is hereby incorporated by reference in its entirety. [0002] The present invention relates to fungicidal compositions and methods of using said compositions. The composition can be used for the protection of hides and skins, for example, from, e.g. After packaging in the tanned state, and / or during long-term storage and transportation, spoilage, degradation and / or deterioration due to uncontrolled fungal growth, so as to prevent, inhibit the degree of damage caused by this growth and / or make the The degree of damage due to this growth is minimal. Background of the invention [0003] Deterioration of hides and skins, especially wet tanned hides and skins, eg due to uncontrolled fungal activity, is a major problem and a major cause of economic loss in the leather and tanning industry. Harmful fungi can c...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C14C1/00
CPCC14C9/00
Inventor 乔治·B·斯托克曼戴维·奥庞格
Owner BUCKMAN LAB INT INC
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