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Compound Chinese herbal medicine immunopotentiator for animal and preparation method thereof

An immune enhancer, Chinese herbal medicine technology, applied in the direction of medical preparations, drug combinations, pharmaceutical formulas containing active ingredients, etc., can solve the problems of difficult product quality, many components, instability, etc., to achieve no harmful residues, formulations Simple, cytokine secretion-promoting effect

Inactive Publication Date: 2009-07-08
广东省农业科学院兽医研究所
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Various Chinese herbal medicines such as Hedyotis diffusa, Radix Astragali, and Codonopsis pilosula can improve or regulate the immune function of the body to varying degrees. The compound Chinese herbal medicine immune enhancer has a more comprehensive or better enhancing effect, but the existing compound preparations have too many components. Complicated, the quality of the product is not only difficult to control, but also unstable. A small compound Chinese herbal medicine immune enhancer was selected from a variety of combinations of different ratios, especially suitable for the southern tropical and subtropical regions. No related reports have been seen so far.

Method used

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  • Compound Chinese herbal medicine immunopotentiator for animal and preparation method thereof
  • Compound Chinese herbal medicine immunopotentiator for animal and preparation method thereof
  • Compound Chinese herbal medicine immunopotentiator for animal and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] In this example, the compound Chinese herbal medicine immune enhancer for animals is prepared from the following raw material components by weight ratio:

[0018] Hedyotis diffusa 10g, Astragalus 40g, Codonopsis 40g.

[0019] The preparation method is as follows: first crush the above-mentioned raw material components, pass through a 40-mesh sieve, and then mix according to the stated weight ratio, add 15 times the weight of deionized water and boil for 3 times, filter while hot, combine the filtrates, and heat at 65°C Concentrate in vacuum to 1g / ml, subpackage, and sterilize under high pressure.

Embodiment 2

[0021] In this example, the compound Chinese herbal medicine immune enhancer for animals is prepared from the following raw material components by weight ratio:

[0022] Hedyotis diffusa 5g, Astragalus 30g, Codonopsis 30g.

[0023] The preparation method is as follows: first crush the above-mentioned raw material components, pass through a 100-mesh sieve, and then mix according to the weight ratio, add 8 times the weight of deionized water and boil for 5 times, filter while hot, combine the filtrates, and heat at 60°C Concentrate in vacuum to 1g / ml, subpackage, and sterilize under high pressure.

Embodiment 3

[0025] In this example, the compound Chinese herbal medicine immune enhancer for animals is prepared from the following raw material components by weight ratio:

[0026] Hedyotis diffusa 15g, Astragalus 50g, Codonopsis 50g.

[0027] The preparation method is as follows: first crush the above-mentioned raw material components, pass through a 60-mesh sieve, and then mix according to the weight ratio, add 10 times the weight of deionized water and boil for 4 times, filter while it is hot, combine the filtrates, and heat at 70°C Concentrate in vacuum to 1g / ml, subpackage, and sterilize under high pressure.

[0028] Now taking the immunopotentiator obtained in Example 1 as an example, chickens and mice are used as animal models to prove its immune enhancing effect on animal bodies through the following experiments. Similar experiments have shown that Example 2 and Example 3 have similar effects. Effect.

[0029] One, immunopotentiator of the present invention is to the immunopote...

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Abstract

The invention discloses a formulation of compound Chinese herbal medicine immunopotentiator used for animals and a preparation method thereof. The compound immunopotentiator is mainly prepared by raw material compositions with the following parts by weight: 5-15 parts of oldenlandia diffusa, 30-50 parts of astragalus root and 30-50 parts of dangshen. The preparation method comprises the steps as follows: firstly, the raw material compositions are crushed, sieved and evenly mixed according to the parts by weight, de-ionized water of 8-15 weight times is added into the mixture, then the mixture is decocted, after the mixture is sieved while hot, the filtrate is combined and separately packaged after vacuum concentration, therefore, the immunopotentiator is prepared by high pressure sterilization. The immunopotentiator is a pure Chinese herbal medicine, has no toxic side effect or harmful residue and does not produce the three wastes or pollutants to the environment; the formulation is simple and the effect is excellent, the immunopotentiator can obviously facilitate lymphopoiesis, greatly improve the humoral immunity function of animals, promote the secretion of cytokines in blood such as IL-2, IFN-gamma, and the like, thus various immunologic functions of the organism can be comprehensively improved.

Description

technical field technical field [0001] The invention relates to the field of formulation and preparation technology of immune enhancer, in particular to a Chinese herbal immune enhancer for animals and a preparation method thereof. technical background [0002] With the rapid development of my country's animal husbandry, the mode of livestock and poultry feeding has also undergone significant changes. The degree of scale and intensification is getting higher and higher. Global warming has changed the form and quantity of animal diseases. The most serious and The remarkable feature is that the decline of the immune function of the body caused by various reasons leads to the occasional failure of vaccine immunity, and the frequent outbreaks and epidemics of conditional infectious diseases, especially bacterial diseases. On the one hand, the farms continue to increase the dose and frequency of vaccine use. , the stress on animals is more frequent, and the growth performance of ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/74A61P37/04
Inventor 王贵平李春玲孙俊颖贾爱卿何子双
Owner 广东省农业科学院兽医研究所
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