Compound tea polyphenol vaginal suppository

A technology of vaginal suppositories and tea polyphenols, which is applied in the field of medicine, can solve the problems of easy-to-contaminate clothing, drug leakage, and affect the effective drug concentration, so as to improve the utilization rate, avoid secondary infection, and eliminate vaginal inflammation.

Inactive Publication Date: 2009-07-22
BEIJING GUIQIANJIN MEDICAL TECH +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

First, the depth of entry into the vagina is not enough, and the drug cannot directly act on the lesion; second, part of the drug flows out after the drug enters the vagina and dissolves, which directly affects the effective drug concentration; third, the inflammatory secretion that flows out together with the drug is very easy to contaminate clothing, creating new opportunities for infection

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0014] Example 1 This example is a surface-treated cotton plug, and a semi-synthetic fatty acid glyceride matrix is ​​adsorbed on the surface of the cotton plug. The preparation method is as follows: after melting the semi-synthetic fatty acid at 80 DEG C, put the cotton plug in at 45 DEG C for 30 seconds, the adsorption is saturated, and the cotton plug forms a layer of protective film.

Embodiment 2

[0015] Example 2 Same as Example 1, the difference is that the matrix used is 1 kg of lanolin, 3 kg of paraffin, 50 kg of semi-synthetic fatty acid glycerides, the heating temperature is 90°C, and the tampon is placed at 50°C for 50 seconds.

Embodiment 3

[0016] Example 3 Same as Example 1, the difference is that the matrix used is 15 kg of lanolin, 5 kg of paraffin, 300 kg of semi-synthetic fatty acid glycerides, the heating temperature is 60°C, and the tampon is placed at 30°C for 360 seconds.

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PUM

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Abstract

The invention discloses a compound tea polyphenol pessary. Drug compositions of the pessary comprise tea polyphenol, seabuckthorn oil, and a common suppository base;; the suppository in vivo is also embedded with tampon; the surface and the inside of the tampon are saturated by the common suppository base so as to keep effective concentration and dosage of drugs; and the compound tea polyphenol pessary is used for treating colpitis, cervicitis, cervical erosion, and other gynecological diseases.

Description

technical field [0001] The invention relates to a compound tea polyphenol vaginal suppository for treating vaginitis, cervicitis, cervical erosion and other gynecological diseases and a preparation method thereof, which is used for topical vaginal administration to treat gynecological diseases and belongs to the field of medicine. technical background [0002] Vaginitis, cervicitis, and cervical erosion are common diseases of women of childbearing age, and the incidence rate accounts for about 60% of women of childbearing age. They affect women's physical and mental health and quality of life. Active prevention and treatment of gynecological inflammation is an important way to protect women's health . [0003] There are many medicines and methods for treating the above-mentioned diseases at present, but these methods and medicines all have many deficiencies and limitations, such as: the side effects of drug therapy with antibiotics and hormones are relatively large, and phys...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/185A61K9/02A61P15/00A61P15/02A61K31/352
Inventor 王爱平林小琪王英明李楠
Owner BEIJING GUIQIANJIN MEDICAL TECH
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