Chinese medicament preparation for tonifying kidney and benefiting brain as well as preparation method and novel use thereof
A traditional Chinese medicine preparation and brain-invigorating technology, which is applied in medical formulas, medical preparations containing active ingredients, and pill delivery, and can solve the problems of no more detailed research on the preparation process and no breakthroughs in clinical applications.
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experiment example 1
[0024] Experimental example 1. Investigation of crushing process conditions
[0025] Considering that the wolfberry and rehmannia glutinosa in the recipe are relatively viscous and the efficiency is low when crushed separately, the following method is tried:
[0026] Take 780g of velvet antler, red ginseng, Poria cocos, yam, Chuanxiong, psoralen, medlar, and Rehmannia glutinosa according to the proportion of the prescription, mix them evenly, grind them in a universal grinder, and collect them through an 80-mesh sieve. Powder amount, calculate the powder collection rate. The results are shown in Table 1.
[0027] Table 1 Pulverization test results
[0028]
[0029] The results show that: using the mixed crushing method, the requirements can be met by passing through the 80-mesh sieve, the powder collection rate is high, the loss is small, and the crushing efficiency is high.
experiment example 2
[0030] Experimental example 2. The investigation of the amount of water added for water extraction
[0031] Take Achyranthes bidentata, Radix Scrophulariae, Ophiopogon japonicus, Schisandra chinensis, Jujube kernel, Polygala, and Angelica according to the ratio of the prescription, and divide them into three groups for testing. The first group added 6 times, 4 times, and 4 times the amount of water. , the second group added 8 times, 6 times, and 6 times the amount of water, and the third group added 10 times, 8 times, and 8 times the amount of water. The amount of water added was determined based on the amount of cream produced. The results are shown in Table 2:
[0032] Table 2: Amount of water added for water extraction
[0033]
[0034] Taking the amount of cream output as an indicator, it can be seen that adding 8 times, 6 times, and 6 times of water is better, and the amount of water added is 8 times, 6 times, and 6 times in production.
experiment example 3
[0035] Experimental Example 3. Investigation of Concentration Process
[0036] Concentrate the water extract obtained according to Experimental Example 2 to a clear paste with a relative density of 1.15 to 1.30 at 80°C. The relative density of the concentrated clear paste is tested with the difficulty of wet granulation as an index, and starch and medicinal powder are added. , mix well, granulate with a swing granulator, and observe the situation of wet granulation. The results are shown in Table 3:
[0037] Table 3 The results of investigation on the density of clear ointment
[0038]
[0039] According to the above verification test results, it is determined that the relative density of the extract is 1.15-1.30 when concentrated to 80°C.
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