Method for preparing compound Sihuang dysentery stopping preparation of traditional Chinese medicine for preventing intestinal diseases of animals

A technology for intestinal diseases, Sihuang Zhili Granules, which is applied in the fields of pharmaceutical formulations, disease resistance to vector-borne diseases, and medical preparations containing active ingredients, etc. It can solve the problems of granules with excellent solubility, thermal instability of medicinal materials, and long drying time and other problems, to achieve the effect of shortening the drying cycle, wide application range and improving production efficiency

Inactive Publication Date: 2009-12-02
TIANJIN SHENGJI GRP CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the preparation method of granules often adopts wet granulation technology, which was most widely used in the preparation of traditional Chinese medicine tablets and granules in the 1950s. However, the traditional process of wet granulation has obvious shortcomings, such as long drying time and unstable heat in medicinal materials. Insufficient loss of more components, while the prepared particles are too hard and have poor solubility and unstable quality

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] The preparation of compound Sihuang Zhili oral liquid is carried out as follows:

[0034] (1) Weigh 150-300 g of Coptidis Rhizome, 150-300 g of Cortex Phellodendri, 50-150 g of Rhubarb, 150-300 g of Radix Scutellariae, 150-300 g of Radix Isatidis, and 50-150 g of Radix Glycyrrhiza by weight;

[0035] (2) Select Chinese medicines of Coptis chinensis, Phellodendron cortex, Rhubarb rhubarb, Scutellaria baicalensis, Radix isatidis, and licorice, pass the inspection, and set aside;

[0036] (3) Add the six flavors of traditional Chinese medicine into the Chinese medicine steam heating extraction tank, add 3 to 5 times of water, soak for 30 minutes, pass in steam, control the temperature to 100°C, heat for 2 hours, filter, depressurize and concentrate until concentrated liquid, so that the relative density of the liquid medicine is 1.02 to 1.03;

[0037] (4) preservative is added in the concentrated solution, and the preservative selects 0.05~0.1% of ethyl platinate;

[003...

Embodiment 2

[0041] Compound Sihuang Zhili Granules are prepared according to the following steps:

[0042] (1) Weigh 150-300 g of Coptidis Rhizome, 150-300 g of Cortex Phellodendri, 50-150 g of Rhubarb, 150-300 g of Radix Scutellariae, 150-300 g of Radix Isatidis, and 50-150 g of Radix Glycyrrhiza by weight;

[0043] (2) Select Chinese medicines of Coptis chinensis, Phellodendron cortex, Rhubarb rhubarb, Scutellaria baicalensis, Radix isatidis, and licorice, pass the inspection, and set aside;

[0044] (3) Add the six flavors of traditional Chinese medicine into the Chinese medicine steam heating extraction tank, add 3 to 5 times of water, soak for 30 minutes, pass in steam, control the temperature to 100°C, heat for 2 hours, filter, depressurize and concentrate until concentrated liquid, so that the relative density of the liquid medicine is 1.02 to 1.03;

[0045] (4) preservative is added in the concentrated solution, and the preservative is selected as sodium benzoate 0.6%;

[0046] ...

Embodiment 3

[0053] Compound Sihuang Zhili Tablets are prepared according to the following steps:

[0054] (1) Weigh 150-300 g of Coptidis Rhizome, 150-300 g of Cortex Phellodendri, 50-150 g of Rhubarb, 150-300 g of Radix Scutellariae, 150-300 g of Radix Isatidis, and 50-150 g of Radix Glycyrrhiza by weight;

[0055] (2) Select Chinese medicines of Coptis chinensis, Phellodendron cortex, Rhubarb rhubarb, Scutellaria baicalensis, Radix isatidis, and licorice, pass the inspection, and set aside;

[0056] (3) Add the six flavors of traditional Chinese medicine into the Chinese medicine steam heating extraction tank, add 3 to 5 times of water, soak for 30 minutes, pass in steam, control the temperature to 100°C, heat for 2 hours, filter, depressurize and concentrate until concentrated liquid, so that the relative density of the liquid medicine is 1.02 to 1.03;

[0057] (4) preservative is added in the concentrated solution, and the preservative is selected as sodium benzoate 0.6%;

[0058] (5)...

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Abstract

The invention discloses a method for preparing a compound Sihuang dysentery stopping preparation of traditional Chinese medicine for preventing intestinal diseases of animals, which is characterized in that the method can be used for preparing compound Sihuang dysentery stopping oral liquid, compound Sihuang dysentery stopping extractums, compound Sihuang dysentery stopping granules and compound Sihuang dysentery stopping tablets. The preparation can be prepared into dosage forms of oral liquid, extractums, granules, tablets, and the like, has high content of effective constituents so as to improve the curative effect, has no residues, no generation of drug resistance and reasonable dosage forms, can be taken by drinking water and has convenient transport and use.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine compound preparations for preventing and treating intestinal diseases of livestock and poultry, in particular to a preparation method of a traditional Chinese medicine compound Sihuang antidiarrheal preparation for preventing and treating intestinal diseases of livestock and poultry. Background technique [0002] Intestinal diseases of livestock and poultry continue to occur, such as poultry colibacillosis, chicken pullorum, duck infectious serositis, pig yellow pullorum, etc., often cause great economic losses to the breeding industry. There are many varieties of Chinese herbal medicines for the treatment of livestock and poultry intestinal diseases, but so far there has been no major breakthrough in application. One of the main reasons is that the product formulation is simple and the preparation process is backward, so it is difficult to meet the needs of production and application, s...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/756A61K9/06A61K9/16A61K9/20A61P1/12A61P31/04
CPCY02A50/30
Inventor 刘珂飞
Owner TIANJIN SHENGJI GRP CO LTD
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