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Bracken pill and preparation method thereof

The technology of anchovy grass and dropping pills is applied in the field of medicine, which can solve the problems of low dissolution rate and dissolution rate, long disintegration time limit, large volume of tablets and capsules, etc., and achieves improved dissolution rate and dissolution rate, and clinical administration. Convenience and the effect of less excipients

Inactive Publication Date: 2013-03-20
谢炜 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Due to the hygroscopicity of the total flavonoids and other components in Pteris vulgaris, the dose of the main drug is small, the volume of the tablets and capsules prepared by the traditional method is large, the disintegration time is relatively long, the dissolution rate and dissolution rate are low, and the amount of excipients is large. People, bedridden patients and patients with dysphagia are inconvenient to take and have poor compliance
[0003] At present, there are no similar oral preparations on the market, and there is no pure Chinese herbal medicine Pteris sativa extract preparations, especially drop pills, which are highly efficient, quick-acting, and highly bioavailable Chinese medicine preparations

Method used

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  • Bracken pill and preparation method thereof
  • Bracken pill and preparation method thereof
  • Bracken pill and preparation method thereof

Examples

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Effect test

example 1

[0016] prescription:

[0017]

[0018] Preparation method: Dissolve Pteris vulgaris extract in ethanol and fully dissolve it to become a dispersed ethanol solution of Pteris vulgaris extract, add molten polyethylene glycol 6000, polyethylene glycol 4000, and polysorbate 80 as a matrix In the middle, stir well until uniform, use simethicone oil or liquid paraffin as coolant, drop into pellets below 15°C, rub the pellets, and dry to obtain.

example 2

[0020] prescription:

[0021]

[0022] Preparation method: Dissolve Pteris vulgaris extract in ethanol and fully dissolve it to become a dispersed ethanol solution of Pteris vulgaris extract, add it to the matrix composed of molten polyethylene glycol 4000 and polysorbate 80, and stir well until uniform , using simethicone oil or liquid paraffin as a cooling agent, drop it into pills below 10°C, rub the pills, and dry them to obtain.

example 3

[0024] prescription:

[0025]

[0026] Preparation method: Dissolve Pteris vulgaris extract in ethanol and fully dissolve it to become a dispersed ethanol solution of Pteris vulgaris extract, add it to the matrix composed of melted polyethylene glycol 6000 and polysorbate 80, and stir well until uniform , using simethicone oil or liquid paraffin as a cooling agent, drop it into pills below 15°C, rub the pills, and dry them to obtain.

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Abstract

The invention relates to a bracken pill and a preparation method thereof. The method comprises the following steps: dissolving bracken extract in a proper solvent; adding the solution into a fused substrate through a dispersive dripping method; evenly stirring the mixture; dripping the mixture; and condensing the mixture into pills.

Description

technical field [0001] The invention belongs to the technical field of medicines, and in particular relates to Pteris japonica dripping pills and a manufacturing method thereof. Background technique [0002] Pteris multifida extract is a Chinese herbal medicine preparation extracted from Chinese herbal medicine Pteris multifida Poir., which mainly contains total flavonoids, sterols, amino acids, and lactones of Pteris multifida Poir. , phenolic substances and other medicinal ingredients, Pteris vulgaris has heat-clearing and detoxifying, dampness-relieving and stranguria-relieving, cooling blood, antibacterial and anti-inflammatory effects, and is often used for bacillary dysentery, enteritis, acute and chronic pyelonephritis, cystitis, urinary tract infection, Recently, it has been reported in the literature that the total flavonoids of Pteris vulgaris has the effect of treating heart and cerebrovascular. Compared with similar drugs, Fengweicao dripping pills have the adva...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/20A61K36/11A61K47/34A61K47/36A61K47/42A61K47/44A61K47/10A61K47/26A61P31/04
CPCY02A50/30
Inventor 谢炜谢金生
Owner 谢炜