Anus injecting iodine intestinal tract contrast agent and application thereof in CT virtual colon-proctoscope

A contrast agent and anus technology, applied in the direction of X-ray contrast agent preparation, etc., can solve the problems of affecting the diagnostic accuracy, short inspection time, unacceptable, etc. Effect

Inactive Publication Date: 2010-08-04
华祖光 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] The biggest defect of the existing CT virtual colonoscopy technology is that it is not easy to accept
Although compared with conventional colonoscopy, there is no intrusion in the intestinal tract and the examination time is short, but the long-term fasting, laxatives, colon lavage and anal inflation of 2 liters still bring a lot of pain to the examinee, which is also the reason One of the reasons why technology has not been popularized as a routine medical examination program in China
At the same time, gas as a contrast agent cannot effectively separate the intestinal residue from the intestinal wall in the presence of residual feces
False positive and false negative results are prone to occur through virtual colonoscopy, which affects the accuracy of diagnosis and further limits the application of this technology

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0054] Weigh 11.8g of sodium iodide, 10mg of dexamethasone (can also be replaced by 2 sticks of dexamethasone injection), and weigh 18g of sodium chloride, dissolve sodium iodide and dexamethasone in about 100ml of water for injection, filter Dissolve sodium chloride in about 100ml water for injection, filter; combine the two filtrates, add water for injection to 2000ml, sterilize, and obtain 2000ml isotonic sodium iodide enema.

[0055] If it is prepared and used on the same day, it does not need to be sterilized.

[0056] The patient's bowel preparation, enhanced CT scanning and virtual colonoscopy computer processing steps are the same as the content of the invention.

Embodiment 2

[0058] Weigh 360g of diatrizoate, 10mg of chlorpheniramine (can be replaced by 2 injections of chlorpheniramine), and 100g of glucose, dissolve diatrizoate and chlorpheniramine in about 400ml of water for injection, filter; Dissolve in about 200mg of water for injection, filter; combine the two filtrates, add water for injection to 2000ml, and sterilize to obtain 2000ml isotonic meglumine diatrizoate enema.

[0059] If it is prepared and used on the same day, it does not need to be sterilized.

Embodiment 3

[0061] Weigh 86.28g of iohexol, 20mg of diphenhydramine, measure 5.1ml of mannitol, dissolve iohexol and diphenhydramine in an appropriate amount of water for injection, and separately dissolve mannitol in an appropriate amount of water for injection, filter, and combine the two Add water for injection to the filtrate to 1000ml, and sterilize to obtain 1000ml isotonic iohexol enema.

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PUM

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Abstract

The invention relates to an anus injecting iodine intestinal tract contrast agent and application thereof in a CT virtual colon-proctoscope contrast agent. The iodine contrast agent is an iodine water preparation and comprises an inorganic iodine agent, an organic iodine agent, other iodine compounds and an iodine-contained food; and the iodine-contained concentration is between 5g/L and 180g/L. By adding water for dissolving the iodine contrast agent and adding or not adding an isoosmotic adjusting agent and an antiallergic medicine, the contrast agent is prepared. The application of the anus injecting iodine intestinal tract contrast agent in preparing the CT virtual colon-proctoscope contrast agent does not need to clean the intestinal tract in advance and has the advantages of reduction of pain of an examined person, lowering of pain and side effects on a patient probably caused by injection twice, improvement of effect and accuracy of virtual colon-proctoscope inspection and effective separation of residues in the intestinal tract and the intestinal wall under the condition of excrement residual, and a preparation method of the iodine contrast agent is simple.

Description

【Technical field】 [0001] The invention relates to a contrast agent in the technical field of CT (X-ray computerized tomography), in particular to an iodine contrast agent and its application in CT virtual colonoscopy contrast agent. 【Background technique】 [0002] X-ray CT is a large-scale medical imaging equipment developed rapidly in recent decades, which plays an important role in the diagnosis of diseases. [0003] In the absence of natural contrast between human organs and structures, we usually artificially introduce certain substances into or around the organs to increase their contrast in medical images such as CT. The contrast substances introduced are called contrast agents (or contrast agent). A CT scan done with contrast material is called an enhanced scan. The diagnosis of some diseases cannot be diagnosed without enhanced scan, so enhanced scan has its unique value. Based on the effective contrast agent and the corresponding image segmentation processing and...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K49/04
Inventor 华祖光沈梅芳
Owner 华祖光
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