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Reservoir eluting stent

An internal stent and implantable technology, applied in the direction of stents, dilators, and medical devices, can solve problems such as embolism and vascular obstruction

Active Publication Date: 2010-08-25
CARDINAL HEALTH SWITZERLAND 515 GMBH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Such detachment may again lead to adverse outcomes including embolization of coating fragments (leading to vascular occlusion)

Method used

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  • Reservoir eluting stent
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Examples

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Abstract

The invention discloses a reservoir eluting stent, especially an expandable medical device including a plurality of elongated struts, forming a substantially cylindrical device which is expandable from a first diameter to a second diameter. A plurality of different beneficial agents may be loaded into different openings within the struts for delivery to the tissue. For treatment of conditions such as restenosis, different agents are loaded into different openings in the device to address different biological processes involved in restenosis and are delivered at different release kinetics matched to the biological process treated. The different agents may also be used to address different diseases from the same drug delivery device. In addition, anti-thrombotic agents may be affixed to at least a portion of the surfaces of the medical device for the prevention of sub-acute thrombosis. Primer layers may be used to ensure that the different agents remain affixed to the device as well as to each other.

Description

technical field This application claims priority to US Provisional Application No. 61 / 148,610, filed January 30, 2009. The present invention relates to tissue supporting medical devices, and more particularly to non-removable expandable devices that are implanted in a body cavity of a living animal or human to support and maintain organs The beneficial agent is delivered to the opening of the intervention site as well as the antithrombotic agent surface coating. Background technique In the past, permanent or biodegradable devices have been developed for implantation in body passages to keep the passage open. These devices are usually introduced percutaneously and delivered transluminally until positioned at the desired location. The device is then expanded mechanically (eg, by expanding a mandrel or balloon disposed within the device), or self-expanding by releasing stored energy upon physical activation. Once expanded within a body cavity, the device (called a stent) is...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61F2/82A61M31/00A61M29/00A61F2/91
CPCA61L2300/416A61L31/16A61L31/10A61F2/91A61F2250/0068A61L2300/604A61P7/02A61P9/10A61P37/06C08L67/04
Inventor S·普赖斯J·R·L·斯坦利A·卢克Y·-P·孙J·杜利L·-G·盖R·科瓦尔西克D·博德里G·斯蒂斯-布拉利C·罗杰斯
Owner CARDINAL HEALTH SWITZERLAND 515 GMBH
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