2-substituent-5-(2,4-dichlorophenyl)-1,3,4-oxadiazole derivative, synthetic method and application thereof
A technology of dichlorophenyl and oxadiazoles, applied in the field containing 2-substituent-5--1, can solve the problems of unsatisfactory soil-borne disease suppression and poor water solubility, and achieve low raw material cost and simple operation , the effect of high yield
Inactive Publication Date: 2010-08-25
GUIZHOU UNIV
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However, such compounds have poor water solubility and are not ideal for inhibiting soil-borne diseases.
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Abstract
The invention discloses a 2-substituent-5-(2,4-dichlorophenyl)-1,3,4-oxadiazole derivative, a synthetic method and application thereof, belonging to the field of chemical industry and pesticides. The compound is expressed in the following general formula in the specification, wherein X is 0 or 2, and R is as defined in the specification. In the synthetic method, 2,4-dichlorophenyl formic acid is used as an initial raw material for synthesizing sulfoether or sulfone compounds; biological activity screening is carried out; and a part of the screened compounds has better inhibiting activity and better application prospect for various plant diseases and particularly for soil-borne diseases.
Description
2-substituent-5-(2,4-dichlorophenyl)-1,3,4-oxadiazole derivatives and their synthesis method and application technical field The invention relates to chemical industry and pesticide, and the specific technology is 2-substituent-5-(2,4-dichlorophenyl)-1,3,4-oxadiazole derivatives and their synthesis method and application. Background technique Soil-borne diseases are generally considered to be the first of the five most difficult diseases in agricultural production due to their extensive and serious damage. With the adjustment of planting structure in our country, the expansion of planting scale and the development of facility agriculture, the occurrence of soil-borne diseases such as blight, verticillium wilt and root rot in crop seedling stage is serious, posing a serious threat to agricultural production. The yield reduction rate reaches 20-40%. However, due to the long-term application of traditional control agents such as Dixon, Pentachlorobenzene, and Carbendazim for ...
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Patent Type & Authority Applications(China)
IPC IPC(8): C07D271/113A01N43/824A01N47/06A01P3/00
Inventor 徐维明宋宝安杨松何江贺呜胡德禹金林红赵云王贞超柏松王建
Owner GUIZHOU UNIV
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