Hydrophilic coat solution applied to surface of medicinal instrument and preparation method thereof

Abstract

The invention discloses hydrophilic coat solution applied to the surface of a medicinal instrument, which comprises modified polyurethane dispersing liquid serving as matrix polymer, hydrophilic polymer and reaction activity crosslinking agent. A preparation method for the hydrophilic coat solution comprises the following steps: (1) dissolving the hydrophilic polymer in water uniformly to form hydrophilic polymer solution, and stirring the solution uniformly; (2) dissolving the matrix polymer in the water uniformly, adding the matrix polymer solution into the hydrophilic polymer solution prepared in the step (1), and stirring the solution uniformly; and (3) adding the reaction activity crosslinking agent into the solution, and stirring the solution uniformly. The aqueous system-based hydrophilic coat solution reduces the used amount of a solvent, and reduces harm to an environment and an operator; the preparation method is simple and easy to operate, and can be applied to the surfaces of multiple medicinal instruments, improve the surface lubricating property of the medicinal instrument, reduce the friction coefficient and improve the effect of lubrication action; and the coating method is a one-step method, avoids processes of plasma pretreatment and the like for materials, is simple and can reduce the cost of the coat.

Description

technical field [0001] The invention relates to a hydrophilic coating system and a preparation method thereof, in particular to a hydrophilic coating system applied to the surface of a medical device, a preparation method thereof, and a method for coating the same on the surface of a medical device. Background of the invention [0002] In the field of medical applications, untreated medical devices such as interventional catheters often have problems with high friction during use. When the catheter is inserted into or pulled out of human tissue, it needs to be lubricated on its surface, so as to reduce the patient's pain and injury to the patient, and at the same time, it is convenient for the operator to operate. Coating on the surface of medical devices has become an effective and necessary means. [0003] Modifying the surface of medical devices to make them highly hydrophobic or highly hydrophilic can reduce the coefficient of friction and improve the effect of lubricat...

AI Technical Summary

Problems solved by technology

The disadvantage of this method is that the substrate needs to be pretreated by plasma, the equipment is expensive and the process is complicated, which greatly increases the product cost