Stauntonia brachyanthera Hand-Mazz saponins components as well as preparation method and application thereof

A technology of fructoside and yellow wax fruit, which is applied in the field of preparation of yellow wax fruit saponins, and achieves the effects of high content, high extraction and separation efficiency, and strong operability
CN101880306BActive Publication Date: 2014-04-23SHENYANG PHARMA UNIVERSITY

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
SHENYANG PHARMA UNIVERSITY
Publication Date
2014-04-23

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Abstract

The invention relates to a Stauntonia brachyanthera Hand-Mazz component as well as a preparation method and application thereof, belonging to the technical field of medicines. The method comprises the following steps of: extracting Stauntonia brachyanthera Hand-Mazz by using water or organic solvents with different concentrations, filtering and recovering the solvents to obtain a concentrated solution; eluting the concentrated solution by using water and an organic solvent through macroporous absorption resin, recovering the solvent to obtain a saponin, or obtaining the saponin from an n-butyl alcohol layer by using an extracting method; then further separating and purifying the saponin by using a normal-phase silicagel column, a reversed phase column and a high efficient liquid phase preparation system; and finally obtaining a monomer or compound with remarkable activity. The Stauntonia brachyanthera Hand-Mazz component of the invention can be singly or combined with other drugs to be used as a raw drug applied to a drug for resisting tumour, resisting inflammation, promoting urination, and treating other diseases. The Stauntonia brachyanthera Hand-Mazz component prepared with the method has high purity, remarkable pharmacological action, simple and convenient method, practicability, low price, safety, suitability for industrialized production.
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Description

technical field

[0001] The invention belongs to the technical field of medicine, and relates to a method for extracting and preparing medicinal raw materials and an application thereof, in particular to a method for preparing and application of saponin components of japonica. Background technique

[0002] Huanglaguo (Stauntonia brachyanthera Hand-Mazz) is a plant of the genus Wild Papaya in the family Akebia. It is distributed in Guizhou, Guangxi and other provinces (regions) in my country. It is an evergreen woody vine. The effects of clearing away heat and diuresis, dredging meridian and activating collaterals, relieving pain and draining pus, clearing milk, etc. are the same as Akebia. The shape of the fruit is basically the same as that of Zhizhizi. Huangla fruit does not crack after ripening, and its color is yellow. Folks also use it as a medicine for predicting seeds; the peel contains many stone cells, and it is used by folks for stones. The leaves are also used as me...

Claims

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