Microchip and method of manufacturing same
A manufacturing method and microchip technology, applied in separation methods, chemical instruments and methods, manufacturing microstructure devices, etc., can solve problems such as difficulty in forming a uniform flow path, and achieve suppression of stagnation, reduction of reproducibility, and suppression of liquid levels highly uneven effect
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Embodiment 1
[0124] Bonding of resin substrate 10 and resin film 20 and thermal annealing
[0125] First, Embodiment 1 will be described. Polymethyl methacrylate and other acrylic resins (manufactured by Asahi Kasei, Delpetto 7 O N H) were molded with an injection molding machine, and a plurality of streams with a width of 50 μm and a depth of 50 μm were produced on a plate-shaped member with an external dimension of 50 mm × 50 mm × 1 mm. The resin substrate 10 is composed of a channel groove 11 and a plurality of through holes 15 having an inner diameter of 2 mm.
[0126] As the resin film 20 , an acrylic resin such as polymethyl methacrylate (manufactured by Mitsubishi Rayon, with a thickness of 75 μm) was cut into a size of 50 mm×50 mm. Then, the resin film 20 is bonded to the bonding surface 12 of the resin substrate 10 with the groove 11 for the flow path, and the press temperature is 90° C. and 10 kgf / cm by a hot press machine. 2 The resin substrate 10 and the resin film 20 are bonde...
Embodiment 2
[0130] Bonding of resin substrate 10 and resin film 20 and thermal annealing
[0131] Example 2 will be described below. Acrylic resin (manufactured by Asahi Kasei, Delpetto 7 O N H) such as transparent resin material polymethyl methacrylate was molded with an injection molding machine, and a 50 μm wide and 50 μm deep plate was produced on a plate-shaped part with an external dimension of 50 mm × 50 mm × 1 mm. A resin substrate 10 composed of a plurality of channel grooves 11 and a plurality of through holes 15 having an inner diameter of 2 mm.
[0132] As the resin film 20 , an acrylic resin such as polymethyl methacrylate (made by Mitsubishi Rayon, manufactured by Mitsubishi Rayon, with a thickness of 75 μm) was cut into 50 mm×50 mm. Then, the resin film 20 is bonded to the bonding surface 12 of the resin substrate 10 with the groove 11 for the flow path, and the press temperature is 90° C. and 10 kgf / cm by a hot press machine. 2 The resin substrate 10 and the resin film 2...
Embodiment 3
[0136] Bonding of resin substrate 10 and resin film 20 and thermal annealing
[0137] Example 3 will be described below. Acrylic resin (manufactured by Asahi Kasei, Delpetto 7 O N H) such as transparent resin material polymethyl methacrylate was molded with an injection molding machine, and a 50 μm wide and 50 μm deep plate was produced on a plate-shaped part with an external dimension of 50 mm × 50 mm × 1 mm. A resin substrate 10 composed of a plurality of channel grooves 11 and a plurality of through holes 15 having an inner diameter of 2 mm.
[0138] As the resin film 20 , an acrylic resin such as polymethyl methacrylate (made by Mitsubishi Rayon, manufactured by Mitsubishi Rayon, with a thickness of 75 μm) was cut into 50 mm×50 mm. Then, the resin film 20 is bonded to the bonding surface 12 of the resin substrate 10 with the groove 11 for the flow path, and the press temperature is 90° C. and 10 kgf / cm by a hot press machine. 2 The resin substrate 10 and the resin film 2...
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