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Oral medicament for treating osteonecrosis of femoral head

A femoral head necrosis and drug technology, applied in drug combination, bone disease, medical formula, etc., can solve the problems of not delaying the development of osteonecrosis, high risk, and high cost

Inactive Publication Date: 2012-05-23
陈守杰
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In surgical treatment, such as drilling decompression, the effective rate can reach about 80%, but it is only suitable for patients before early collapse; although total hip replacement has the characteristics of wide indication range and good effect, it is risky , The cost is high, and this method is only used when the condition is serious and drug treatment is ineffective
Although there have been published literatures on the treatment of femoral head necrosis with traditional Chinese medicine, most of them can only relieve pain, and cannot delay the development of osteonecrosis and completely cure it.

Method used

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  • Oral medicament for treating osteonecrosis of femoral head

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0207] Embodiment 1: (water decoction)

[0208] Raw material formula:

[0209] Chuanxiong 10g; Corydalis 15g; Safflower 10g;

[0210] Ground soft-shelled turtle 10g; Salvia miltiorrhiza 20g; Caulis Spatholobus 20g;

[0211] Angelica 15g; Paeoniae Alba 15g; Astragalus 30g;

[0212] Codonopsis 12g; Shouwu 15g; Eucommia charcoal 15g;

[0213] Dipsacus 15g; Morinda officinalis 12g; Achyranthes bidentata 15g;

[0214] Lycium barbarum 15g; Schisandra 12g; Drynaria 18g;

[0215] Atractylodes macrocephala 10g; Poria cocos 12g; Duhuo 10g;

[0216] Sangjisheng 18g; Papaya 15g; Fangji 12g;

[0217] Gentiana 15g; Millennium Jian 9g; Pittogonia bark 15g;

[0218] Fangfeng 10g; Guizhi 10g; Zhichuan Aconitum 9g;

[0219] Aconitum 9g; Atractylodes 12g; Earthworm 12g;

[0220] Gastrodia elata 15g; Oyster 20g; Alisma 10g;

[0221] Smilax 20g; Licorice 9g.

[0222] steps:

[0223] (1) screen out each raw material drug according to the ratio of each raw material, and remove impurities...

Embodiment 2

[0225] Embodiment 2: (granule)

[0226] Raw material formula:

[0227] Chuanxiong 9g; Corydalis 18g; Safflower 9g;

[0228] Ground soft-shelled turtle 9g; Salvia miltiorrhiza 21g; Spatholobus 21g;

[0229] Angelica 17g; Paeoniae Alba 14g; Astragalus 26g;

[0230] Codonopsis 11g; Shouwu 14g; Eucommia charcoal 13g;

[0231] Dipsacus 13g; Morinda officinalis 14g; Achyranthes bidentata 13g;

[0232] Lycium barbarum 13g; Schisandra 11g; Drynaria 16g;

[0233] Atractylodes macrocephala 9g; Poria cocos 14g; Duhuo 9g;

[0234] Sangjisheng 16g; Papaya 17g; Fangji 14g;

[0235] Gentiana 10g; Qiannianjian 7g; Pittosporum bark 13g;

[0236] Fangfeng 9g; Guizhi 9g; Zhichuan Aconitum 7g;

[0237] Aconitum 7g; Atractylodes 11g; Earthworm 14g;

[0238] Gastrodia elata 13g; Oyster 21g; Alisma 9g;

[0239] Smilax 25g; Licorice 8g.

[0240] steps:

[0241] (1) screen out each raw material drug according to the ratio of each raw material, and remove impurities for later use;

[0242]...

Embodiment 3

[0244] Embodiment 3: (tablet)

[0245] Raw material formula:

[0246] Chuanxiong 11g; Corydalis 13g; Safflower 11g;

[0247] Ground soft-shelled turtle 11g; Salvia miltiorrhiza 19g; Caulis Spatholobus 19g;

[0248] Angelica 13g; Paeoniae Alba 11g; Astragalus 33g;

[0249]Codonopsis 18g; Shouwu 11g; Eucommia charcoal 18g;

[0250] Dipsacus 18g; Morinda officinalis 11g; Achyranthes bidentata 18g;

[0251] Lycium barbarum 18g; Schisandra 9g; Drynaria 17g;

[0252] Atractylodes macrocephala 11g; Poria cocos 10g; Duhuo 11g;

[0253] Sangjisheng 13g; Papaya 13g; Fangji 10g;

[0254] Gentiana 17g; Millennium Jian 8g; Pittogonia bark 18g;

[0255] Fangfeng 11g; Guizhi 11g; Zhichuan Aconitum 11g;

[0256] Aconitum 11g; Atractylodes 10g; Earthworm 10g;

[0257] Gastrodia elata 18g; Oyster 19g; Alisma 11g;

[0258] Smilax 28g; Licorice 11g.

[0259] steps:

[0260] (4) screen out each bulk drug according to the ratio of each raw material, and remove impurities for subsequent ...

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Abstract

The invention discloses an oral medicament for treating osteonecrosis of the femoral head, which is mainly prepared from the following materials according to a certain weight ratio: szechuan lovage rhizome, rhizoma corydalis, red flower, Chinese polyphaga, salvia miltiorrhiza, suberect spatholobus stem, Chinese angelica, white paeony root, astragalus, codonopsis pilosula, prepared tuber of multiflower knotweed, eucommia ulmoides oliver, himalayan teasel root, medicinal indianmulberry root, medicinal cyathula root, medlar, Chinese magnoliavine fruit, fortune's drynaria rhizome, largehead atractylodes rhizome, indian buead, heracleum, Chinese taxillus twig, papaya, fangji root, root of largeleaf gentian, obscured homalomena rhizome, erythrina indica lam, divaricate saposhnikovia root, cassia twig, prepared common monkshood mother root, prepared kusnezoff monkshood root, swordlike atractylodes rhizome, earthworm, tall gastrodia tuber, oyster, oriental waterplantain rhizome, glabrous greenbrier rhizome and liquorice. The materials can be prepared into any common formulation for oral administration. The medicament for treating the osteonecrosis of the femoral head has the advantages ofexact curative effect and high recovery rate by adopting treating means of traditional Chinese medicine according to the theory of traditional Chinese medicine and the non-surgical treatment principle of Western medicine.

Description

technical field [0001] The invention relates to an oral medicine for treating femoral head necrosis, which belongs to the field of traditional Chinese medicines. Background technique [0002] Necrosis of the femoral head, also known as avascular necrosis of the femoral head, is called osteoarthritis or bone wilt in traditional Chinese medicine. Most of them are caused by trauma, drugs (mainly long-term heavy use of hormone drugs), alcohol stimulation (mainly long-term heavy drinking), rheumatism, blood disease, diving sickness, burns and other diseases. In short, various reasons destroy the blood supply of the femoral head , causing necrosis. If not treated in time, it can lead to permanent disability. [0003] The prior art mainly contains operative treatment and non-operative treatment to the treatment of femoral head necrosis. In surgical treatment, such as drilling decompression, the effective rate can reach about 80%, but it is only suitable for patients before early...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61P19/08A61K35/64A61K35/56A61K36/8988A61K35/618A61K35/62
Inventor 陈守杰
Owner 陈守杰