Implantable front-end acquisition device for brain electrical signal and manufacturing method thereof

Abstract

The invention discloses an implantable front-end acquisition device for a brain electrical signal and a manufacturing method thereof. The front-end acquisition device mainly comprises an input filter, a main amplifier device, a second amplifier, a multiplexing unit, an output buffer and a system controller. After the input filter filters the received brain electrical signal, the brain electrical signal is sent to the main amplifier device to be amplified; the inhibited and amplified signal is subjected to direct-current disorder processing; after being amplified by the second amplifier, the processed signal is output to the multiplexing unit; and the multiplexing unit and the output buffer output the selected brain electrical signal under the control of the system controller. In the manufacturing method of the front-end acquisition device, an active negative feedback circuit is manufactured at the main amplifier device to inhibit the direct-current disorder of the acquired signal; anda fully differential source electrode negative feedback circuit and a low-frequency band pass filter are adopted to inhibit the low-frequency noise of the acquired signal. The implantable front-end acquisition device contributes to multi-channel synchronous acquisition of massive neural signals and guarantees the microminiaturization and the practicability of an implantable brain metering interface device.

Description

technical field [0001] The invention relates to the technical field of signal acquisition integration of an implantable brain nerve signal reading system, in particular to an implantable front-end collector of brain electrical signals and a design method thereof. Background technique [0002] Integrated weak signal acquisition is widely used in signal acquisition interface devices between implanted cranial nerves and external computer data processing systems due to its high integration and low power consumption. However, the contradictory problems of the weak and massive EEG signals and the low power consumption and miniaturization of implanted brain-computer interface devices have become the crux of the practical problems. The existing implantable EEG signal front-end reading circuit consumes too much chip area, and the chip area continues to increase with the integration of large-scale multi-channel arrays, and because the cut-off frequency of the front-end acquisition dev...

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Problems solved by technology

[0004] The present invention aims at problems such as the large chip area brought about by the implementation of the front-end collector in the prior art, resulting in a large trauma area during brain implantation and damage to intracranial tissue caused by overheating of the chip, and provides an implantable EEG signal sensor. Type front-end collector and design method thereof, the front-end collector and design method thereof of the present invention utilizes the fully differential active feedback structure to realize the front-end acquisition and acquisition technology of micro-noise, micro-power consumption, and low area consumption, which is conducive to the acquisition of large-scale neural signals Multi-channel synchronous acquisition and complete reproduction of original EEG data ensure the miniaturization and practicality of implantable brain-computer interface devices

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