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Handheld ultralow field MRI (magnetic resonance imaging) system based on SQUID (superconducting quantum interference device)

An ultra-low-field, hand-held technology that is used in medical science, sensors, diagnostic recording/measurement, etc., to solve problems such as large cooling structures, inability to package SQUIDs together, and irregularities

Active Publication Date: 2012-10-24
SHANTOU DONGFANG ULTRASONIC TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] SQUID (Superconducting Quantum Interference Device, Superconducting Quantum Interference Device) is currently the most sensitive magnetic flux detector in the world. It is very small and suitable for making a hand-held ultra-low field MRI system. Refrigerant refrigeration cools the SQUID, and its cooling structure is too large to be packaged together with the SQUID. If the machine is narrowed to a hand-held range, it will inevitably cause the polarizing coil and the gradient coil to be on the same side of the object to be detected. The magnetic field generated by it is very different from the standard magnetic field. The magnetic fields generated by each coil overlap and are very irregular. It is impossible to use the existing ultra-low field MRI magnetic resonance imaging algorithm to reconstruct images, which is also a difficult place to break through
Based on the above reasons, there is currently no hand-held ultra-low field MRI using SQUID as the core component.

Method used

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  • Handheld ultralow field MRI (magnetic resonance imaging) system based on SQUID (superconducting quantum interference device)
  • Handheld ultralow field MRI (magnetic resonance imaging) system based on SQUID (superconducting quantum interference device)
  • Handheld ultralow field MRI (magnetic resonance imaging) system based on SQUID (superconducting quantum interference device)

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Experimental program
Comparison scheme
Effect test

Embodiment approach 1

[0033] Such as figure 1 with Image 6 As shown, this SQUID-based handheld ultra-low field MRI system includes hardware and software. The hardware includes a smart handheld device 1, an excitation coil module 2, a polarization coil module 3, a gradient coil module 4, and a receiving coil module. 5, SQUID6, cooling module 7, data acquisition module 8, main control module 9, power control module 10, interface module 11, probe shell 12 and magnetic shield 13; Magnetic shield 13 is located in probe shell 12, magnetic shield The bottom of 13 is provided with opening, and opening is connected with the bottom of probe housing 12; Receive coil module 5, SQUID6 and cooling module 7 are all located in magnetic shield 13, receive coil module 5 is installed in the opening of magnetic shield 13, cooling The module 7 is in contact with the SQUID6; the polarizing coil module 3 and the gradient coil module 4 are all located inside the probe housing 12 and distributed on the outside of the mag...

Embodiment approach 2

[0045] In the case where other situations are the same as Embodiment 1, the difference is that at least three gradient coils are geometrically coded so that each voxel unit of the object to be measured is in a different frequency, phase, and excitation layer. In the software part In the magnetic field parameter transformation module, magnetic field parameter transformation is performed on all magnetic resonance signals acquired in a space volume, and the operation is repeated continuously.

Embodiment approach 3

[0047] When other conditions are the same as those of Embodiment 1 or Embodiment 2, the difference is that the excitation coil modules are not arranged in the probe housing, but are distributed around the measured object.

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Abstract

The invention relates to a handheld ultralow field MRI (magnetic resonance imaging) system based on an SQUID (superconducting quantum interference device). The system provided by the invention comprises a hardware part and a software part, wherein the hardware part encapsulates a polarizing coil module, a gradient coil module, a receiving coil module, a cooling module and the SQUID in a detectionhead housing; and a magnetic field parameter transformation module is arranged in the software part. After the polarizing coil module, the gradient coil module, the receiving coil module, the coolingmodule and the SQUID are encapsulated in the detection head housing, the cooling module provides an ultralow temperature working environment for the SQUID without using liquid helium cooling; and themagnetic field parameter transformation module transforms irregular magnetic filed parameters detected by the SQUID into the magnetic field parameters suitable for using the existing MRI algorithm, so that the existing MRI algorithm can be used for reconstructing images to achieve the handheld of the MRI system. The system has low operation and maintenance costs, can substitute for 0.1-1 T permanent magnet MRI equipment and is suitable for medium and small-sized hospitals.

Description

technical field [0001] The invention relates to a magnetic resonance imaging device, in particular to a SQUID-based hand-held ultra-low field MRI system. Background technique [0002] Existing MRI (Magnetic Resonance Imaging, magnetic resonance imaging), its hardware equipment mainly comprises computer, magnet (or polarized coil), gradient coil, exciting coil, magnetic flux detector, receiving coil, data acquisition module, main control module, Power control module and interface module. Among them, the excitation coil is placed close to the measured object to generate excitation signals to different parts of the tested object; the magnet (or polarized coil) and the gradient coil are evenly arranged around the measured object to generate regular Magnetic field; the power control module is electrically connected to the data acquisition module, the main control module and the magnetic flux detector; the receiving coil is used to receive the magnetic resonance signal of the mea...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61B5/055
Inventor 李德来林国臻
Owner SHANTOU DONGFANG ULTRASONIC TECH
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