Biomolecular network exhibition analysis system and analysis method thereof

A biomolecular network and analysis system technology, applied in the field of biomolecular network display and analysis system and its analysis, can solve the problems of biological reality that are far apart, and achieve the effect of displaying relevant results

Inactive Publication Date: 2011-08-03
EAST CHINA NORMAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, in most cases, this kind of network is treated as a simple relational network with no direction and no weight, which is far from the biological reality of the protein interaction network.

Method used

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  • Biomolecular network exhibition analysis system and analysis method thereof
  • Biomolecular network exhibition analysis system and analysis method thereof
  • Biomolecular network exhibition analysis system and analysis method thereof

Examples

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Embodiment 1

[0099] In this embodiment, the online analysis method of the biomolecular network display analysis system of the present invention is used to analyze the protein interaction system of the plant model organism Arabidopsis thaliana. Wherein, the structure of the biomolecular network display and analysis system of the present invention is the same as that of the above-mentioned embodiments, and will not be repeated here.

[0100] Such as Figure 4 Shown is the analysis effect diagram of the online display analysis system of the biomolecular network display analysis system of the present invention for analyzing the protein interaction system of the plant model organism Arabidopsis thaliana. The biomolecular network display and analysis system of the present invention systematically displays the functional cooperation information of the target gene in the network from the perspective of the molecular network, and through the introduction of regulatory information, mutation phenotyp...

Embodiment 2

[0122] In this embodiment, the biomolecular network display and analysis system of the present invention is used to display and analyze the drug small molecule functional network system off-line. Wherein, the structure of the biomolecular network display and analysis system of the present invention is the same as that of the above-mentioned embodiments, and will not be repeated here.

[0123] Such as Figure 5 Shown is the analysis effect diagram of the off-line display and analysis system of the biomolecular network display and analysis system of the present invention. The biomolecular network display and analysis system of the present invention uses the drug target gene relationship, drug side effect information, and drug treatment disease information to construct the drug small molecule functional network submitted by users, so that researchers can discover the mechanism of drug action and new drug targets for the treatment of specified diseases. Provides an excellent entr...

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Abstract

The invention provides a biomolecular network exhibition analysis system which comprises an online analysis module, an offline analysis module, a network data structure module, a network assignment module, a network exhibition module, a network analysis module, a database, a document data interface, a temporary data table and a data output module. The invention can automatically establish and annotate the relevant biomolecular network based on internet resource connection through a biomolecular database based on attention protein and gene sets. The invention also provides an analysis method of the biomolecular network exhibition analysis system, which integrates the existing research annotation information in system biology and bioinformatics based on the biomolecular network characteristics, uses a free network as a base model, combines the biomolecular network characteristics and refines node and relation types.

Description

technical field [0001] The invention relates to the field of biomolecular network display analysis, in particular to a biomolecular network display analysis system and an analysis method thereof. Background technique [0002] Biological network is a system in which various molecules in organisms interact to complete various complex biological functions. Research at the network level helps to understand the internal mechanism of various complex events in organisms as a whole. Cellular gene transcription regulation network, metabolic network or signal transduction network are the most common biomolecular network systems. These networks are often composed of many different biomolecular "elements," the most important of which are genes and proteins. But for the "system", the key is not the components, but the relationship between the constituent elements, as well as the state characteristic information of the original components. From a biomolecular perspective, a relationshi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G06F19/12
Inventor 石铁流李鹏
Owner EAST CHINA NORMAL UNIV
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